Patents by Inventor Maryann Gray

Maryann Gray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunological combination compositions and methods
    Publication number: 20080089911
    Abstract: Immununological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader for lipidation and PspA for the protein portion. The antigen can be OspC and the lipoprotein OspA. The components of the composition are co-administered. A potentiated immunological response is obtained by the compositions and methods.
    Type: Application
    Filed: May 18, 2007
    Publication date: April 17, 2008
    Inventors: Robert Becker, Robert Huebner, Maryann Gray, Karen Biscardi, Lorne Erdile, Bruno Guy
  • Immunological combination compositions and methods
    Patent number: 7235243
    Abstract: Immununological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader for lipidation and PspA for the protein portion. The antigen can be OspC and the lipoprotein OspA. The components of the composition are co-administered. A potentiated immunological response is obtained by the compositions and methods.
    Type: Grant
    Filed: July 1, 2005
    Date of Patent: June 26, 2007
    Assignee: Connaught Laboratories, Inc.
    Inventors: Robert S. Becker, Robert C. Huebner, Maryann Gray, Karen S. Biscardi, Lorne F. Erdile, Bruno Guy
  • Immunological combination compositions and methods
    Publication number: 20060110408
    Abstract: Immununological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader for lipidation and PspA for the protein portion. The antigen can be OspC and the lipoprotein OspA. The components of the composition are co-administered. A potentiated immunological response is obtained by the compositions and methods.
    Type: Application
    Filed: July 1, 2005
    Publication date: May 25, 2006
    Inventors: Robert Becker, Robert Huebner, Maryann Gray, Karen Biscardi, Lorne Erdile, Bruno Guy
  • Immunological combination compositions and methods
    Patent number: 6984385
    Abstract: Immunological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader for lipidation and PspA for the protein portion. The antigen can be OspC and the lipoprotein OspA. The components of the composition are co-administered. A potentiated immunological response is obtained by the compositions and methods.
    Type: Grant
    Filed: March 12, 2002
    Date of Patent: January 10, 2006
    Assignee: Connaught Laboratories, Inc.
    Inventors: Robert S. Becker, Robert C. Huebner, Maryann Gray, Karen S. Biscardi, Lorne F. Erdile, Bruno Guy
  • Expression of lipoproteins
    Publication number: 20050171343
    Abstract: Heterologous lipidated proteins formed recombinantly are disclosed and claimed. The expression system can be E. coli. The heterologous lipidated protein has a leader sequence which does not naturally occur with the protein portion of the lipidated protein. The lipidated protein can have the Borrelia OspA leader sequence. The protein portion can be OspC, PspA, UreA, Ure B, or a fragment thereof. Methods and compositions for forming and employing the proteins are also disclosed and claimed.
    Type: Application
    Filed: February 6, 2003
    Publication date: August 4, 2005
    Inventors: Robert Huebner, Lorne Erdile, Donald Warakomski, Robert Becker, Maryann Gray, Derek Pyle
  • Immunological combination compositions and methods
    Publication number: 20020131983
    Abstract: Immunological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader for lipidation and PspA for the protein portion. The antigen can be OspC and the lipoprotein OspA. The components of the composition are co-administered. A potentiated immunological response is obtained by the compositions and methods.
    Type: Application
    Filed: March 12, 2002
    Publication date: September 19, 2002
    Inventors: Robert S. Becker, Robert C. Huebner, Maryann Gray, Karen S. Biscardi, Lorne F. Erdile, Bruno Guy
  • Immunological combination compositions and methods
    Patent number: 6379675
    Abstract: Immunological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader for lipidation and PspA for the protein portion. The antigen can be OspC and the lipoprotein OspA. The components of the composition are co-administered. A potentiated immunological response is obtained by the compositions and methods.
    Type: Grant
    Filed: January 19, 1996
    Date of Patent: April 30, 2002
    Assignee: Connaught Laboratories, Inc.
    Inventors: Robert S. Becker, Robert C. Huebner, Maryann Gray, Karen S. Biscardi, Lorne F. Erdile, Bruno Guy