Patents by Inventor Marybeth Sharkey

Marybeth Sharkey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chromophore compositions and methods of making and using the same
    Patent number: 9523679
    Abstract: Chromophore compositions and methods of making and using the same are provided. Aspects of the chromophore compositions include a chromophore component having a chromophore, such as a fluorescent dye moiety, stably associated with a prosthetic group binding cavity of a metalloprotein. Also provided are methods of making, methods of use, systems and kits related to the subject fluorescent compositions.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: December 20, 2016
    Assignee: Becton, Dickinson and Company
    Inventors: Majid Mehrpouyan, Oleg Guryev, Marybeth Sharkey
  • Phosphorothioate oligonucleotide-labeling of white blood cells
    Patent number: 9347863
    Abstract: The present invention provides labeling and capture reagents that comprise phosphorothioate oligonucleotides (PS-ODN). The PS-ODN bind to all white blood cells (leukocytes) in an indiscriminative fashion and enable the labeling, capture, or concentration of leukocytes in a manner that preserves the antigenic integrity of the cells. Methods for the use of phosphorothioate oligonucleotides are provided.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: May 24, 2016
    Assignee: Becton, Dickinson and Company
    Inventors: Majid Mehrpouyan, Marybeth Sharkey
  • CHROMOPHORE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20150362484
    Abstract: Chromophore compositions and methods of making and using the same are provided. Aspects of the chromophore compositions include a chromophore component having a chromophore, such as a fluorescent dye moiety, stably associated with a prosthetic group binding cavity of a metalloprotein. Also provided are methods of making, methods of use, systems and kits related to the subject fluorescent compositions.
    Type: Application
    Filed: June 30, 2015
    Publication date: December 17, 2015
    Inventors: Majid Mehrpouyan, Oleg Guryev, Marybeth Sharkey
  • Chromophore compositions and methods of making and using the same
    Patent number: 9110070
    Abstract: Chromophore compositions and methods of making and using the same are provided. Aspects of the chromophore compositions include a chromophore component having a chromophore, such as a fluorescent dye moiety, stably associated with a prosthetic group binding cavity of a metalloprotein. Also provided are methods of making, methods of use, systems and kits related to the subject fluorescent compositions.
    Type: Grant
    Filed: February 10, 2014
    Date of Patent: August 18, 2015
    Assignee: Becton, Dickinson and Company
    Inventors: Majid Mehrpouyan, Oleg Guryev, Marybeth Sharkey
  • Polymersome Encapsulation of Hydrophobic Fluorescent Polymers
    Publication number: 20150140549
    Abstract: Described herein are aqueous soluble polymersomes that encapsulate one or more hydrophobic fluorescent polymers and methods of their preparation and use.
    Type: Application
    Filed: September 30, 2014
    Publication date: May 21, 2015
    Inventors: Majid MEHRPOUYAN, Shumeye MAMO, Marybeth SHARKEY
  • Phosphorothioate Oligonucleotide-Labeling of White Blood Cells
    Publication number: 20150087005
    Abstract: The present invention provides labeling and capture reagents that comprise phosphorothioate oligonucleotides ODN). The PS-ODN bind to all white blood cells (leukocytes) in an indiscriminative fashion and enable the labeling, capture, or concentration of leukocytes in a manner that preserves the antigenic integrity of the cells. Methods for the use of phosphorothioate oligonucleotides are provided.
    Type: Application
    Filed: December 17, 2012
    Publication date: March 26, 2015
    Applicant: Becton, Dickinson and Company
    Inventors: Majid Mehrpouyan, Marybeth Sharkey
  • CHROMOPHORE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20140234855
    Abstract: Chromophore compositions and methods of making and using the same are provided. Aspects of the chromophore compositions include a chromophore component having a chromophore, such as a fluorescent dye moiety, stably associated with a prosthetic group binding cavity of a metalloprotein. Also provided are methods of making, methods of use, systems and kits related to the subject fluorescent compositions.
    Type: Application
    Filed: February 10, 2014
    Publication date: August 21, 2014
    Inventors: Majid Mehrpouyan, Oleg Guryev, Marybeth Sharkey