Patents by Inventor Maryna V. lvanchenko

Maryna V. lvanchenko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AAV VECTORS ENCODING MINI-PCDH15 AND USES THEREOF
    Publication number: 20220315948
    Abstract: Aspects of the disclosure relate to compositions, nucleic acids, vectors, viruses, and methods useful for treating hearing loss and/or blindness, for example, Usher Syndrome type IF. The present disclosure provides isolated nucleic acids, vectors, and rAAV.9.PHP.B comprising a transgene encoding a mini-PCDH15, and methods of treating hearing loss using the same. The present disclosure also provides a gRNA associated with a base editor to correct one or more mutations in PCDH15 for treating hearing loss and/or vision loss.
    Type: Application
    Filed: April 24, 2020
    Publication date: October 6, 2022
    Applicants: President and Fellows of Harvard College, Ohio State Innovation Foundation, Massachusetts Eye and Ear Infirmary
    Inventors: David P. Corey, Artur Indzhykulian, Marcos Sotomayor, Maryna V. lvanchenko, Cole W. D. Peters