Abstract: Method for the realization Hof a calcium phosphate-based biomaterial in form of granules and/or agglomerates of re-absorbable granules which can be used in the biomedical industry as, e.g., bone fillers, for increasing the bone mass, as a sealing for the internal orthopaedic prosthesis, for releasing drugs and/or medicaments and/or other substances beneficial for the organism. A calcium phosphate-based biomaterial in form of granules and/or aggregates thereof obtained according to such method.

Abstract: Method for providing a biocompatible bone implant adapted to fill a bone cavity or lacuna including the steps of providing granular elements in form of granules and/or granule aggregates, providing at least one primary polymeric solution including a biopolymer, at least partly coating the granular elements with the primary polymeric solution, obtaining coated granular elements including a biopolymer coating, providing a cross-linking solution, dipping the coated granular elements in the cross-linking solution, waiting a period of time referred to as “jellification time” of between 30 seconds and 1 hour, in which during said waiting step there occurs the cross-linking of the biopolymer coating of the granular elements with the cross-linking solution and the jellification of the coating, with the aim of obtaining a cohesive biocompatible implant including granular elements and a bio-reabsorbable biopolymer gel; biocompatible bone implant obtained through such method.

Abstract: Method for the realization of a calcium phosphate-based biomaterial in form of granules and/or agglomerates of re-absorbable granules which can be used in the biomedical industry as, e.g., bone fillers, for increasing the bone mass, as a sealing for the internal orthopaedic prosthesis, for releasing drugs and/or medicaments and/or other substances beneficial for the organism. A calcium phosphate-based biomaterial in form of granules and/or aggregates thereof obtained according to such method.