Patents by Inventor Masaaki II

Masaaki II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION USED FOR THERAPEUTIC TREATMENT OF SKIN DISEASE
    Publication number: 20240180971
    Abstract: The present invention provides an excellent composition for therapeutically treating a skin disease (e.g., a drug, a quasi-drug or a cosmetic). The composition for therapeutically treating a skin disease according to the present invention contains exosomes secreted from stem cells (for example, adipose-derived stem cells), in which the stem cells contain drug-encapsulating nanoparticles comprising a drug (for example, statin, estrogen, retinoic acid and ascorbic acid) encapsulated in nanoparticles containing a bioabsorbable polymer.
    Type: Application
    Filed: January 5, 2024
    Publication date: June 6, 2024
    Applicant: Novumcella Inc.
    Inventor: Masaaki II
  • Cell preparation for treating cartilage tissue-related disorder
    Patent number: 11213550
    Abstract: To provide a spheroid-containing cell preparation exhibiting a high therapeutic effect for a cartilage tissue-related disorder as a treatment target. A prophylactic or therapeutic agent for a cartilage tissue-related disorder contains, as an effective ingredient, a spheroid including cultured mesenchymal stem cells.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: January 4, 2022
    Assignee: NIPPON SHOKUBAI CO., LTD.
    Inventors: Tomomi Makino, Takuma Nakada, Masaaki Ii
  • STATIN-CONTAINING NANOPARTICLE PREPARATION FOR ENHANCING FUNCTION OF STEM CELLS FOR TREATING INFLAMMATORY DISEASE, AND FUNCTIONALLY ENHANCED STEM CELLS CONTAINING SAME FOR TREATING INFLAMMATORY DISEASE
    Publication number: 20210038725
    Abstract: A statin-encapsulated nanoparticle contains a bioabsorbable polymer and statin encapsulated in the nanoparticle. Suitable bioabsorbable polymers include a polylactic acid (PLA) polymer or a polylactic acid-glycolic acid (PLGA) copolymer. The statin-encapsulated nanoparticle can be used to enhance the function of a stem cell. The stem cell can be a stem cell for treating an inflammatory disease.
    Type: Application
    Filed: October 21, 2020
    Publication date: February 11, 2021
    Inventors: Masaaki II, Yasuhiko TABATA
  • COMPOSITION USED FOR THERAPEUTIC TREATMENT OF SKIN DISEASE
    Publication number: 20200345783
    Abstract: The present invention provides an excellent composition for therapeutically treating a skin disease (e.g., a drug, a quasi-drug or a cosmetic). The composition for therapeutically treating a skin disease according to the present invention contains exosomes secreted from stem cells (for example, adipose-derived stem cells), in which the stem cells contain drug-encapsulating nanoparticles comprising a drug (for example, statin, estrogen, retinoic acid and ascorbic acid) encapsulated in nanoparticles containing a bioabsorbable polymer.
    Type: Application
    Filed: January 23, 2019
    Publication date: November 5, 2020
    Applicant: Novumcella Inc.
    Inventor: Masaaki Ii
  • STATIN-CONTAINING NANOPARTICLE PREPARATION FOR ENHANCING FUNCTION OF STEM CELLS FOR TREATING INFLAMMATORY DISEASE, AND FUNCTIONALLY ENHANCED STEM CELLS CONTAINING SAME FOR TREATING INFLAMMATORY DISEASE
    Publication number: 20190134201
    Abstract: A statin-encapsulated nanoparticle contains a bioabsorbable polymer and statin encapsulated in the nanoparticle. Suitable bioabsorbable polymers include a polylactic acid (PLA) polymer or a polylactic acid-glycolic acid (PLGA) copolymer. The statin-encapsulated nanoparticle can be used to enhance the function of a stem cell. The stem cell can be a stem cell for treating an inflammatory disease.
    Type: Application
    Filed: April 27, 2017
    Publication date: May 9, 2019
    Inventors: Masaaki II, Yasuhiko TABATA
  • Statin-encapsulated nanoparticle preparation for enhancing stem cell function, stem cell with enhanced function containing statin-encapsulated nanoparticle, and method for producing same
    Patent number: 10278926
    Abstract: A preparation containing a statin-encapsulated nanoparticle obtained by encapsulating statin in a nanoparticle containing a bioabsorbable polymer is disclosed. The nanoparticle has a number average particle diameter of less than 1000 nm. The preparation is used to enhance the function of a stem cell. A stem cell with an enhanced function is disclosed. The stem cell takes up and contains the statin-encapsulated nanoparticle.
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: May 7, 2019
    Assignee: FOUNDATION FOR BIOMEDICAL RESEARCH AND INNOVATION AT KOBE
    Inventors: Masaaki Ii, Yasuhiko Tabata
  • STATIN-ENCAPSULATED NANOPARTICLE PREPARATION FOR ENHANCING STEM CELL FUNCTION, STEM CELL WITH ENHANCED FUNCTION CONTAINING STATIN-ENCAPSULATED NANOPARTICLE, AND METHOD FOR PRODUCING SAME
    Publication number: 20170319504
    Abstract: The present invention is a preparation containing a statin-encapsulated nanoparticle obtained by encapsulating statin in a nanoparticle containing a bioabsorbable polymer. The nanoparticle has a number average particle diameter of less than 1000 nm. The preparation is used to enhance the function of a stem cell. The present invention is a stem cell with an enhanced function. The stem cell takes up and contains the statin-encapsulated nanoparticle.
    Type: Application
    Filed: November 11, 2015
    Publication date: November 9, 2017
    Inventors: Masaaki II, Yasuhiko TABATA