Patents by Inventor Masaaki Murai
Masaaki Murai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9978316Abstract: A display apparatus including a drive control section that performs control to repeatedly switch between a drive time period during which a backlight emits light and a rest time period during which the backlight does not emit light, in an alternating manner with a prescribed period. The drive control section controls a ratio between the drive time period and the rest time period, and controls the amount of drive current supplied to the backlight during the drive time period. The drive control section sets the rest time period to be a prescribed time period and controls the amount of the drive current for a range where an adjustment value is less than a prescribed value, and sets the drive current to a prescribed value and makes the rest time period shorter than the prescribed time period for a range where the adjustment value is greater than the prescribed value.Type: GrantFiled: January 7, 2016Date of Patent: May 22, 2018Assignee: EIZO CorporationInventors: Akinori Hayashi, Hideaki Hashimoto, Masaaki Murai, Daiki Takeda
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Publication number: 20160117999Abstract: A display apparatus including a drive control section that performs control to repeatedly switch between a drive time period during which a backlight emits light and a rest time period during which the backlight does not emit light, in an alternating manner with a prescribed period. The drive control section controls a ratio between the drive time period and the rest time period, and controls the amount of drive current supplied to the backlight during the drive time period. The drive control section sets the rest time period to be a prescribed time period and controls the amount of the drive current for a range where an adjustment value is less than a prescribed value, and sets the drive current to a prescribed value and makes the rest time period shorter than the prescribed time period for a range where the adjustment value is greater than the prescribed value.Type: ApplicationFiled: January 7, 2016Publication date: April 28, 2016Inventors: Akinori HAYASHI, Hideaki HASHIMOTO, Masaaki MURAI, Daiki TAKEDA
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Patent number: 8901155Abstract: A method for treating a TRPV1-mediated disease by administering to a patient a therapeutically effective amount of a compound or a salt thereof having the following formula [I]: wherein A represents a lower alkylene group or a lower alkenylene group; R1 represents a hydrogen atom, an unsubstituted or substituted alkyl group or an unsubstituted or substituted alkenyl group; and R2 and R3 are the same or different and represent a hydrogen atom, an unsubstituted lower alkyl group or a lower alkyl group substituted by a monocyclic cycloalkyl group, a polycyclic cycloalkyl group or an aryl group.Type: GrantFiled: November 19, 2012Date of Patent: December 2, 2014Assignee: Santen Pharmaceutical Co., Ltd.Inventors: Kenji Oki, Fumio Tsuji, Chikako Setoguchi, Iwao Seki, Masaaki Murai, Minoru Sasano
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Patent number: 8445529Abstract: An indole compound having a carbamoyl group, a ureido group and a substituted oxy group having the following formula (1) or a salt thereof: In the formula (1), R1 represents a hydrogen atom, an alkyl group, a hydroxy group, or an alkoxy group; R2 represents a hydrogen atom, an alkyl group, a cycloalkyl group, an aryl group, or a heterocyclic group; R3 represents a halogen atom, an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, an aryl group, a heterocyclic group an alkoxy group, an alkenyloxy group, an alkynyloxy group, a cycloalkyloxy group, an aryloxy group or a heterocyclic oxy group; m represents 0, 1, 2, or 3.Type: GrantFiled: July 14, 2009Date of Patent: May 21, 2013Assignee: Santen Pharmaceutical Co., Ltd.Inventors: Kenji Kawashima, Hiroshi Enomoto, Minoru Yamamoto, Masaaki Murai
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Patent number: 8193237Abstract: Disclosed is a compound represented by the general formula (1) or a salt thereof. The compound or a salt thereof has an inhibitory activity on IKK? and is therefore useful as preventive and/or therapeutic agent for a disease associated with IKK?. In the formula, R1 represents a hydrogen atom, a lower alkyl group, an aryl group, a hydroxy group, or the like; R2 represents a halogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, or the like; and m represents 0, 1, 2, or the like.Type: GrantFiled: January 15, 2008Date of Patent: June 5, 2012Assignee: Santen Pharmaceutical Co., Ltd.Inventors: Hiroshi Enomoto, Kenji Kawashima, Kazuhiro Kudou, Minoru Yamamoto, Masaaki Murai, Takaaki Inaba, Noriko Ishizaka
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Patent number: 8088817Abstract: A compound represented by the following formula (1) or a salt thereof: The compound has an inhibitory activity on the production of interleukin-6, and is therefore useful as a therapeutic agent for a disease associated with interleukin-6, ocular inflammatory diseases and the like. In the formula, R1 represents a halogen atom, a hydrogen atom, a lower alkyl group which may have a substituent, a formyl group, or a lower alkylcarbonyl group which may have a substituent, R2 represents a bicyclic hydrocarbon group which may have a substituent or a bicyclic heterocyclic group which may have a substituent, R3 represents a hydrogen atom, a lower alkyl group which may have a substituent, an aryl group which may have a substituent, or an acyl group.Type: GrantFiled: August 25, 2009Date of Patent: January 3, 2012Assignee: Santen Pharmaceutical Co., Ltd.Inventors: Kenji Kawashima, Noriko Kawashima, Hiroshi Enomoto, Minoru Yamamoto, Masaaki Murai
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Patent number: 7977371Abstract: Objects of the present invention are to study on the synthesis of a novel pyrrole derivative having a ureido group and an aminocarbonyl group as substituents or a salt thereof, to find a pharmacological effect of the derivative or a salt thereof, and to find a medicinal agent which has a prophylactic and/or therapeutic effect on a retinal disease or the like through oral administration. A compound represented by the general formula (1) or a salt thereof has an inhibitory activity against the production of interleukin-6 and/or an inhibitory effect on choroidal neovascularization, and is therefore useful as a prophylactic and/or therapeutic agent for a disease associated with interleukin-6, an ocular inflammatory disease and/or a retinal disease.Type: GrantFiled: February 26, 2008Date of Patent: July 12, 2011Assignee: Santen Pharmaceutical Co., Ltd.Inventors: Kenji Kawashima, Hiroshi Enomoto, Noriko Ishizaka, Minoru Yamamoto, Kazuhiro Kudou, Masaaki Murai, Takaaki Inaba, Kazuyoshi Okamoto
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Publication number: 20110124668Abstract: The present invention relates to synthetic studies on novel indole derivatives having a carbamoyl group, a ureido group and a substituted oxy group or a salt thereof, and pharmaceutical actions of the derivatives. The compound and a salt thereof represented by the general formula (1) has an IKK? inhibitory activity and is useful as a preventive and/or therapeutic agent for diseases considered to be associated with IKK?.Type: ApplicationFiled: July 14, 2009Publication date: May 26, 2011Applicant: SANTEN PHARMACEUTICAL CO., LTD.Inventors: Kenji Kawashima, Hiroshi Enomoto, Minoru Yamamoto, Masaaki Murai
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Publication number: 20100261911Abstract: An object of the present invention is to find a novel pharmacological action of a urea compound having a structure represented by the general formula [I]. The urea compound having a structure represented by the general formula [I] or a salt thereof has an excellent therapeutic effect on a TRPV1-mediated disease. In the formula, A represents a lower alkylene group or a lower alkenylene group; R1 represents a hydrogen atom, an alkyl group which may have a substituent or an alkenyl group which may have a substituent; and R2 and R3 are the same or different and represent a hydrogen atom or a lower alkyl group which may be substituted by a monocyclic cycloalkyl group, a polycyclic cycloalkyl group, or an aryl group.Type: ApplicationFiled: October 16, 2008Publication date: October 14, 2010Inventors: Kenji Oki, Fumio Tsuji, Chikako Setoguchi, Iwao Seki, Masaaki Murai, Minoru Sasano
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Patent number: 7741346Abstract: An object of the present invention is to find new pharmacological actions of urea compounds having structure represented by the general formula [1]. The urea compounds having the structure represented by the general formula [1] have excellent angiogenesis inhibitory actions. [wherein “A” is —(NR4)—, —(CR5R6)— or —O—, “B” is alkylene or alkenylene, R1, R2, R4, R5 and R6 are hydrogen, alkyl, alkenyl, adamantylalkyl or the like, R3 is aryl or an unsaturated heterocycle, and X is oxygen or sulfur].Type: GrantFiled: November 29, 2002Date of Patent: June 22, 2010Assignee: Santen Pharmaceutical Co., Ltd.Inventors: Hidehito Matsuoka, Kazuo Nishimura, Hisayuki Seike, Hiroyuki Aono, Masaaki Murai
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Publication number: 20100099675Abstract: Objects of the present invention are to study on the synthesis of a novel pyrrole derivative having a ureido group and an aminocarbonyl group as substituents or a salt thereof, to find a pharmacological effect of the derivative or a salt thereof, and to find a medicinal agent which has a prophylactic and/or therapeutic effect on a retinal disease or the like through oral administration. A compound represented by the general formula (1) or a salt thereof has an inhibitory activity against the production of interleukin-6 and/or an inhibitory effect on choroidal neovascularization, and is therefore useful as a prophylactic and/or therapeutic agent for a disease associated with interleukin-6, an ocular inflammatory disease and/or a retinal disease.Type: ApplicationFiled: February 26, 2008Publication date: April 22, 2010Applicant: SANTEN PHARMACEUTICAL CO., LTD.Inventors: Kenji Kawashima, Hiroshi Enomoto, Noriko Ishizaka, Minoru Yamamoto, Kazuhiro Kudou, Masaaki Murai, Takaaki Inaba, Kazuyoshi Okamoto
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Publication number: 20100041628Abstract: Disclosed is a compound represented by the general formula (1) or a salt thereof. The compound or a salt thereof has an inhibitory activity on IKK? and is therefore useful as preventive and/or therapeutic agent for a disease associated with IKK?. In the formula, R1 represents a hydrogen atom, a lower alkyl group, an aryl group, a hydroxy group, or the like; R2 represents a halogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, or the like; and m represents 0, 1, 2, or the like.Type: ApplicationFiled: January 15, 2008Publication date: February 18, 2010Inventors: Hiroshi Enomoto, Kenji Kawashima, Kazuhiro Kudou, Minoru Yamamoto, Masaaki Murai, Takaaki Inaba, Noriko Ishizaka
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Publication number: 20080161270Abstract: An object of the present invention is to find new pharmacological actions of urea compounds having structure represented by the general formula [1]. The urea compounds having the structure represented by the general formula [1] have excellent angiogenesis inhibitory actions. [wherein “A” is —(NR4)—, —(CR5R6)— or —O—, “B” is alkylene or alkenylene, R1, R2, R4, R5 and R6 are hydrogen, alkyl, alkenyl, adamantylalkyl or the like, R3 is aryl or an unsaturated heterocycle, and X is oxygen or sulfur.Type: ApplicationFiled: January 25, 2008Publication date: July 3, 2008Applicant: SANTEN PHARMACEUTICAL CO., LTD.Inventors: Hidehito Matsuoka, Kazuo Nishimura, Hisayuki Seike, Hiroyuki Aono, Masaaki Murai
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Publication number: 20050014800Abstract: An object of the present invention is to find new pharmacological actions of urea compounds having structure represented by the general formula [1]. The urea compounds having the structure represented by the general formula [1] have excellent angiogenesis inhibitory actions. [wherein “A” is —(NR4)—, —(CR5R6)— or —O—, “B” is alkylene or alkenylene, R1, R2, R4, R5 and R6 are hydrogen, alkyl, alkenyl, adamantylalkyl or the like, R3 is aryl or an unsaturated heterocycle, and X is oxygen or sulfur.Type: ApplicationFiled: November 29, 2002Publication date: January 20, 2005Inventors: Hidehito Matsuoka, Kazuo Nishimura, Hisayuki Seike, Hiroyuki Aono, Masaaki Murai
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Patent number: 4028495Abstract: A time division communication system is constructed with modular time division switches. The system includes 2n switch modules (n is a positive integer), and each switch module is composed of m line control units (m is a positive integer) for accomodating m lines and a time division switch control unit capable of controlling 2m line control units. The switch modules are assembled in pairs, and cross connections are provided between the switch modules of each pair to enable the respective time division switch control units to mutually send and receive time-division multiplexed information. In addition, the input and output terminals of the corresponding time division switch control units of the respective switch module pairs are interconnected so that respective ones of the module pairs may mutually send and receive time-division multiplexed information.Type: GrantFiled: December 29, 1975Date of Patent: June 7, 1977Assignee: Nippon Electric Company, Ltd.Inventors: Hiroshi Funamo, Toshiro Kunihiro, Masaaki Murai