Patents by Inventor Masaaki Ozawa

Masaaki Ozawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200000927
    Abstract: A Ras protein degradation inducing molecule that can induce degradation of Ras proteins, and a pharmaceutical composition that contains this Ras protein degradation inducing molecule are provided. The Ras protein degradation inducing molecule is a conjugate of a Ras protein affinity molecule which has affinity to Ras proteins, and a proteolysis-inducing tag which has affinity to protease and does not inhibit proteolysis of proteins by the protease.
    Type: Application
    Filed: November 13, 2017
    Publication date: January 2, 2020
    Applicant: Tokyo University of Science Foundation
    Inventors: Etsuko MIYAMOTO, Masaaki OZAWA
  • Publication number: 20190369111
    Abstract: A molecular kinetics evaluation method is provided which involves: a step for dosing a human or non-human animal with a proteolysis-inducing molecule, which is a conjugate of a proteolysis induction tag, i.e., a molecule which has affinity for protease and which does not inhibit proteolysis by protease, and a specific protein affinity molecule having affinity to a specific protein, and inducing proteolysis of the specific protein in vivo in the human or non-human animal; and a step for evaluating the molecular kinetics of the specific protein affinity molecules or the proteolysis-inducing molecules by detecting proteolysis of the specific proteins in a sample which is at least part of the human or non-human animal.
    Type: Application
    Filed: November 13, 2017
    Publication date: December 5, 2019
    Applicant: Tokyo University of Science Foundation
    Inventors: Etsuko MIYAMOTO, Masaaki OZAWA
  • Publication number: 20190367719
    Abstract: Provided are: a material having high thermal conductivity that includes an alumina fiber sheet and a resin, wherein the material having high thermal conductivity includes 20-90% by mass of the alumina fiber sheet; and a method for producing a material having high thermal conductivity, the method including (1) a step for preparing a fiber sheet that includes an alumina source by electrostatic spinning or dry spinning in which a dispersion including an alumina source and a water-soluble polymer is used as a spinning material, (2) a step for firing the fiber sheet including an alumina source to prepare an alumina fiber sheet, and (3) a step for impregnating the alumina fiber sheet with a resin solution having a resin concentration of 10% by weight or less.
    Type: Application
    Filed: January 17, 2018
    Publication date: December 5, 2019
    Applicants: UNIVERSITY OF FUKUI, NISSAN CHEMICAL CORPORATION
    Inventors: Koji Nakane, Shuya Gao, Akiyoshi Ogoshi, Takeshi Suwa, Tadayuki Isaji, Masaaki Ozawa
  • Patent number: 10498101
    Abstract: A method for producing an organic microdisk structure 40, which is characterized by comprising: a cladding layer formation step 1 wherein a cladding layer 12 is formed by printing a first ink 11 that contains a fluorine-containing hyperbranched polymer on a substrate 10 by an inkjet method; a core layer formation step 2 wherein a core layer 22 is formed by printing a second ink 21 that contains a laser dye and a triazine-based hyperbranched polymer containing no fluorine on the cladding layer 12 by an inkjet method; and an etching step 3 wherein the cladding layer 12 is etched using a solvent 31 that dissolves only the fluorine-containing hyperbranched polymer. Consequently, an unconventional novel method for producing an organic microdisk structure with use of an inkjet method is able to be provided.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: December 3, 2019
    Assignees: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Yuji Oki, Hiroaki Yoshioka, Kei Yasui, Masaaki Ozawa
  • Patent number: 10494480
    Abstract: A composition comprising both a polymer which contains triazine-ring-containing repeating units represented by formula (17) and a crosslinking agent which consists of either a poly-functional epoxy compound or a polyfunctional (meth)acrylic compound can be photo-cured even without the addition of an initiator to yield a cured film having a high refractive index and high heat resistance. Thus, a photocurable film-forming composition that comprises a triazine-ring-containing polymer, which can achieve, even without the addition of a metal oxide by the polymer alone, high heat resistance, high transparency, a high refractive index, high solubility and low volume shrinkage, and that is curable even without the addition of an acid generator can be provided.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: December 3, 2019
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Naoya Nishimura, Masaaki Ozawa
  • Publication number: 20190316495
    Abstract: Provided is a mechanical lash adjuster including a plunger, a housing put into thread engagement with the plunger in an axial direction to form a thread engagement portion, the plunger engaging member fixed and retained in a circumferential direction of the thread engagement portion, and a coil spring urging the plunger in a direction opposite to a urging-force acting direction of a coil spring. A lead and flank angles of threads forming the thread engagement portion are set such that when an axial load acts on the plunger in either of a plunger extension and contraction directions, the plunger is made self-sustaining, and when the plunger swings by an amount corresponding to a backlash due to a lateral load, the plunger slides and rotates at the thread engagement portion to move in an axial-load acting direction.
    Type: Application
    Filed: June 17, 2016
    Publication date: October 17, 2019
    Inventors: Michihiro KAMEDA, Hiroyuki OZAWA, Masaaki INOUE
  • Publication number: 20190314508
    Abstract: A p53 degradation inducing molecule which can induce degradation of p53 proteins or p53 composites, and a pharmaceutical composition containing said p53 degradation inducing molecule are provided. This p53 degradation inducing molecule is a conjugate of a p53 affinity molecule which has affinity for p53 proteins or p53 composites, and a proteolysis induction tag which has affinity for protease and which does not inhibit proteolysis of proteins by protease.
    Type: Application
    Filed: November 13, 2017
    Publication date: October 17, 2019
    Applicant: Tokyo University of Science Foundation
    Inventors: Etsuko MIYAMOTO, Masaaki OZAWA
  • Patent number: 10353041
    Abstract: In one embodiment, an MRI apparatus, includes a static magnetic field magnet configured to generate a static magnetic field, a gradient coil configured to generate a gradient magnetic field, a transmission and reception coil configured to transmit an RF signal and receive a magnetic resonance signal, and processing circuitry. The processing circuitry determines whether or not a prescan for calculating a correction value that corrects a phase error is skippable or reducible based on an imaging condition of a main scan, and executes a scan including at least the main scan in accordance with a result of the determination.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: July 16, 2019
    Assignee: Toshiba Medical Systems Corporation
    Inventors: Hiroki Kondo, Shinya Ozawa, Masaaki Umeda, Yoshimori Kassai, Naoyuki Takabayashi
  • Patent number: 10301502
    Abstract: A curable composition for coating comprising: (a) a fluorine-containing highly branched polymer obtained by polymerization of a monomer A having two or more radical polymerizable double bonds in a molecule of the monomer A and a monomer B having a fluoroalkyl group and at least one radical polymerizable double bond in a molecule of the monomer B, in the presence of a polymerization initiator C at an amount of 5% by mole to 200% by mole per the number of moles of the monomer A, (b) at least one surface modifier selected from the group consisting of a perfluoropolyether compound and a silicone compound, (c) an active energy ray-curable polyfunctional monomer, and (d) a polymerization initiator that generates radicals by irradiation with an active energy ray; a cured film obtained from the composition; and a hard coating film obtained by use of the composition.
    Type: Grant
    Filed: December 1, 2011
    Date of Patent: May 28, 2019
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Masayuki Haraguchi, Motonobu Matsuyama, Tomoko Misaki, Masaaki Ozawa
  • Publication number: 20190085199
    Abstract: A nonlinear optically active copolymer having satisfactory orientation characteristics and able to allow for reduction in heat-induced orientation relaxation of a nonlinear optical material, and a nonlinear optical material obtained using the copolymer. The copolymer including at least a repeating unit A having adamantyl group and a repeating unit B having a nonlinear optically active moiety in one molecule, and an organic nonlinear optical material including the copolymer as a component.
    Type: Application
    Filed: March 16, 2017
    Publication date: March 21, 2019
    Applicants: KYUSHU UNIVERSITY, NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Shiyoshi YOKOYAMA, Hiroki MIURA, Daisuke MAEDA, Kei YASUI, Tsubasa KASHINO, Masaaki OZAWA
  • Patent number: 10227457
    Abstract: It is an object to provide a compound that can provide a molded article and a coating film excellent not only in solubility in an organic solvent, but also in miscibility with/dispersibility in a matrix resin, causing no aggregation in a matrix resin, excellent in surface modification property, and having high transparency. A fluorine-containing highly branched polymer obtained by polymerizing a monomer A having two or more radical polymerizable double bonds in the molecule thereof with a monomer B having a fluoroalkyl group and at least one radical polymerizable double bond in the molecule thereof in the presence of a polymerization initiator C in a content of 5% by mol or more and 200% by mol or less, based on the total molar amount of the monomer A and the monomer B; and a resin composition comprising the polymer.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: March 12, 2019
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Masayuki Haraguchi, Motonobu Matsuyama, Masaaki Ozawa, Misao Miyamoto
  • Patent number: 10174164
    Abstract: Provided is a triazine ring-containing hyperbranched polymer comprising the repeating unit structure represented by formula (1) and having one or more triazine ring terminals, said one or more triazine ring terminals being capped with a compound that differs from the diamine compound serving as the starting material for the polymer and has at least two active hydrogen groups. In addition to the polymer itself exhibiting high heat resistance, high transparency, a high refractive index, high light resistance, high solubility, and low volume shrinkage, it is also possible to use the polymer to provide a composition for film formation capable of yielding a thick film having high hardness. (In formula (1), R and R? each independently represent a hydrogen atom, an alkyl group, an alkoxy group, an aryl group, or an aralkyl group, and Ar represents a divalent organic group containing an aromatic ring and/or a heterocyclic ring.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: January 8, 2019
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Naoya Nishimura, Kei Yasui, Masaaki Ozawa
  • Patent number: 10106701
    Abstract: With a photocurable composition for film formation which comprises a polymer containing a repeating unit structure having a triazine ring, for example, one represented by the following formula (17), a crosslinking agent, an ultraviolet absorber, and a light stabilizer, it is possible to produce a cured film which has a high refractive index and satisfactory weatherability
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: October 23, 2018
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Takahiro Kaseyama, Naoya Nishimura, Masaaki Ozawa
  • Patent number: 10020513
    Abstract: There is provided a novel slurry composition for forming a lithium secondary battery electrode which can improve homogeneity of an electrode active material and a conductive assistant even without using an organic solvent and can improve the binding of an electrode active material and a conductive assistant with an electrode collector, and a lithium secondary battery with improved charge/discharge cycle characteristics and battery capacity. A slurry composition for forming a lithium secondary battery electrode, characterized by comprising an electrode active material (A), a conductive assistant (B), and a pulverized cellulose fiber (C) as an aqueous binder, and a lithium secondary battery electrode and a lithium secondary battery which are obtained using the composition, and an aqueous binder used for the composition.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: July 10, 2018
    Assignees: NISSAN CHEMICAL INDUSTRIES, LTD., IWATE UNIVERSITY
    Inventors: Hisato Hayashi, Masaaki Ozawa, Osamu Uesugi, Yoshihiro Kadoma
  • Publication number: 20180164289
    Abstract: Provided are: a protein degradation inducing tag which is a molecule that has affinity with proteases and does not inhibit degradation of a protein by proteases; a protein degradation inducing molecule that is a conjugate of at least one protein degradation inducing tag and at least one protein binding molecule that binds to a protein; and a usage of those.
    Type: Application
    Filed: June 15, 2016
    Publication date: June 14, 2018
    Applicant: Tokyo University of science Foundation
    Inventors: Etsuko MIYAMOTO, Masaaki OZAWA
  • Patent number: 9920143
    Abstract: A fluorine-containing highly branched polymer obtained by polymerizing a polyfunctional monomer A that has two or more radically polymerizable double bonds and all or a portion of which has a bisphenol structure, a monomer B having a fluoroalkyl group and at least one radically polymerizable double bond, within a molecule, and a monomer C having at least one ring-opening polymerizable group selected from the group including an epoxy group and an oxetanyl group, and having at least one radically polymerizable double bond, within a molecule, under the presence of a polymerization initiator D with an amount of 5% by mole to 200% by mole to the number of moles of the polyfunctional monomer A; an epoxy resin composition including the polymer; and an epoxy resin cured product obtained from the resin composition.
    Type: Grant
    Filed: June 6, 2013
    Date of Patent: March 20, 2018
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Tomoko Misaki, Motonobu Matsuyama, Masayuki Haraguchi, Masaaki Ozawa
  • Publication number: 20170264066
    Abstract: A method for producing an organic microdisk structure 40, which is characterized by comprising: a cladding layer formation step 1 wherein a cladding layer 12 is formed by printing a first ink 11 that contains a fluorine-containing hyperbranched polymer on a substrate 10 by an inkjet method; a core layer formation step 2 wherein a core layer 22 is formed by printing a second ink 21 that contains a laser dye and a triazine-based hyperbranched polymer containing no fluorine on the cladding layer 12 by an inkjet method; and an etching step 3 wherein the cladding layer 12 is etched using a solvent 31 that dissolves only the fluorine-containing hyperbranched polymer. Consequently, an unconventional novel method for producing an organic microdisk structure with use of an inkjet method is able to be provided.
    Type: Application
    Filed: September 4, 2015
    Publication date: September 14, 2017
    Applicants: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Yuji OKI, Hiroaki YOSHIOKA, Kei YASUI, Masaaki OZAWA
  • Publication number: 20170242189
    Abstract: An optical waveguide which has sufficient orientation characteristics and its manufacturing processes are simple to be suitable for the manufacture of electro-optic elements and that can be reduced the power consumption by its large electro-optic characteristics and further can be thinned and stacked, and the material thereof. This material is characterized in a polymer compound that includes an oxazoline structure in a side chain, and an acid generator or a polyvalent carboxylic acid.
    Type: Application
    Filed: September 2, 2015
    Publication date: August 24, 2017
    Applicants: KYUSHU UNIVERSITY, NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Shiyoshi YOKOYAMA, Kazuhiro YAMAMOTO, Hiromu SATO, Daisuke MAEDA, Masaaki OZAWA, Kei YASUI
  • Patent number: 9708486
    Abstract: There is provided a highly branched lipophilic polymer that is excellent in blending and dispersing properties in a matrix resin, and is possible to provide surface modification properties such as excellent lipophilicity (anti-fingerprint property) and the like to a coating that is obtained from the resin composition while the intrinsic transparency of the resin is not impaired; and a photopolymeizable composition comprising the highly branched lipophilic polymer. A highly branched lipophilic polymer obtained by polymerizing a monomer A containing two or more radically polymerizable double bonds per molecule and a monomer B containing a C6-30 alkyl group or a C3-30 alicyclic group and at least one radically polymerizable double bond per molecule in the presence of 5 to 200 mol % of a polymerization initiator C relative to the number of moles of the monomer A. A photopolymeizable composition comprising the highly branched lipophilic polymer.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: July 18, 2017
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Motonobu Matsuyama, Masayuki Haraguchi, Masaaki Ozawa
  • Patent number: 9695281
    Abstract: Disclosed is a triazine ring-containing hyperbranched polymer containing a repeating unit structure represented by the expression (1). By this means, it is possible to achieve a triazine ring-containing polymer which, alone, has high heat resistance, high transparency, high refractive index, high light resistance, high solubility, low volume shrinkage without adding metal oxides; and also a membrane-forming composition containing the same. In the formula, R and R? represent independently a hydrogen atom, an alkyl group, an alkoxy group, an aryl group, or an aralkyl group, and A represents an alkylene group optionally having a branched or alicyclic structure of 1 to 20 carbon atoms.
    Type: Grant
    Filed: August 23, 2011
    Date of Patent: July 4, 2017
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Naoya Nishimura, Masaaki Ozawa, Yasuyuki Koide