Patents by Inventor Masaaki TORII

Masaaki TORII has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Porous implantable devices
    Patent number: 11534283
    Abstract: Porous implantable devices for housing one or more therapeutic agents are disclosed herein. The implantable devices include a porous outer wall defining an interia or void. The interior void houses a carrier material carrying a first therapeutic agent. The implantable devices are made by patterning at least a portion of a polymerizable substrate into a polymerized three-dimensional porous outer wall surrounding an interior void. This can be achieved by two-photon polymerization techniques. A first therapeutic agent is then added to the interior void, which is then sealed. Methods of treating diseases using the implantable devices are disclosed herein. The methods include implanting the implantable device at a target area and locally releasing a therapeutically effective dosage of a first therapeutic agent from the interior void. The implantable devices can also be used in methods of screening potentially therapeutic agents for desired biological responses.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: December 27, 2022
    Assignees: CHILDREN'S NATIONAL MEDICAL CENTER, UNIVERSITY OF MARYLAND, COLLEGE PARK
    Inventors: Alexander I. Son, Kazue Hashimoto-Torii, Masaaki Torii, Paul D. Morton, Seiji Ishii, Justin Opfermann, Judy Liu, John Fisher, Marco Santoro, Peter C.W. Kim
  • POROUS IMPLANTABLE DEVICES
    Publication number: 20200289250
    Abstract: Porous implantable devices for housing one or more therapeutic agents are disclosed herein. The implantable devices include a porous outer wall defining an interior void. The interior void houses a carrier material carrying a first therapeutic agent. The implantable devices are made by patterning at least a portion of a polymerizable substrate into a polymerized three-dimensional porous outer wall surrounding an interior void. This can be achieved by two-photon polymerization techniques. A first therapeutic agent is then added to the interior void, which is then sealed. Methods of treating diseases using the implantable devices are disclosed herein. The methods include implanting the implantable device at a target area and locally releasing a therapeutically effective dosage of a first therapeutic agent from the interior void. The implantable devices can also be used in methods of screening potentially therapeutic agents for desired biological responses.
    Type: Application
    Filed: September 6, 2018
    Publication date: September 17, 2020
    Inventors: Alexander I. SON, Kazue HASHIMOTO-TORII, Masaaki TORII, Paul D. MORTON, Seiji ISHII, Justin OPFERMANN, Judy LIU, John FISHER, Marco SANTORO, Peter C.W. KIM
  • Treatment of learning disabilities and other neurological disorders with SK channel inhibitor(s)
    Patent number: 10555989
    Abstract: Methods for treating learning disabilities associated with fetal alcohol syndrome and other neurological disorders by administering SK channel blockers, antagonists, inhibitors or modifiers like tamapin.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: February 11, 2020
    Assignee: Children's National Medical Center
    Inventors: Kazue Hashimoto-Torii, Masaaki Torii, Mohammad Shahid, Hiroki Morizono
  • TREATMENT OF LEARNING DISABILITIES AND OTHER NEUROLOGICAL DISORDERS WITH SK CHANNEL INHIBITOR(S)
    Publication number: 20180280472
    Abstract: Methods for treating learning disabilities associated with fetal alcohol syndrome and other neurological disorders by administering SK channel blockers, antagonists, inhibitors or modifiers like tamapin.
    Type: Application
    Filed: October 13, 2016
    Publication date: October 4, 2018
    Applicant: Children's National Medical Center
    Inventors: Kazue HASHIMOTO-TORII, Masaaki TORII, Mohammad SHAHID, Hiroki MORIZONO