Abstract: The present invention provides medicinal compositions characterized by comprising as the active ingredient either a compound represented by a formula [I] or a pharmaceutically acceptable composite thereof; [wherein X represents oxygen or sulfur; R1 represents e.g., C1-4 alkyl, phenyl optionally substituted, etc.; Q1 represents spacer consisted of 0 to 3 carbon atoms; R2 represents, e.g., phenyl optionally substituted; R3 represents, e.g., hydrogen, C1-4 alkyl, or a group represented by the following formulae; —CONH—R6; R4 and R5 represent e.g., nitro, cyano, C1-4 alkylcarbonyl, respectively]; in particular, medicine which is useful as therapeutic and/or protective drugs for inflammatory diseases and/or allergic diseases by improving sick conditions accompanied with the stimulated phospholipase A(2) activity.

Abstract: A compound represented by the formula [I]: [I] (wherein X represents oxygen, sulfur, NR4, or CHR5; Y represents oxygen or sulfur; R1 represents C1-6 alkyl, etc.; R2 represents optionally substituted phenyl, etc.; and R3 represents optionally substituted C1-6 alkyl, a group represented by any of the following formulae, etc.) [II] or a pharmaceutically acceptable composite of the compound; a medicinal composition containing any of these as an active ingredient; and a use thereof, etc.

Abstract: The present invention provides medicinal compositions characterized by containing as the active ingredient either a compound represented by a general formula (1) or a pharmaceutically acceptable composite thereof, 1

Abstract: The present invention provides medicinal compositions characterized by comprising as the active ingredient either a compound represented by a formula [I] or a pharmaceutically acceptable composite thereof; 1

Abstract: The present invention provides medicinal compositions characterized by containing as the active ingredient either a compound represented by a general formula (1) or a pharmaceutically acceptable composite thereof, [wherein X represents oxygen or sulfur; R1 represents hydrogen, C1-4 alkyl, etc.; R2 represents, e.g., phenyl optionally substituted by A1; R3 represents, e.g., hydrogen, C1-4 alkyl optionally substituted by A2, or a group represented by either one of the following formulae; R represents oxygen, sulfur, or a group represented by a formula (N—G)], in particular, inhibitors of phospholipase A(2) activity; use of the compositions; and compounds represented by a general formula (1—1); wherein X, R1, R2, R3 and G1 are the same as defined in the description.

Abstract: The present invention provides medicinal compositions characterized by containing as the active ingredient either a compound represented by a general formula (1) or a pharmaceutically acceptable composite thereof, 1