Patents by Inventor Masaharu Ichihara

Masaharu Ichihara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic hexapeptides having antibiotic activity
    Patent number: 6884868
    Abstract: This invention relates to new polypeptide compound represented by general formula (I), wherein R1, R2, R3, R4, R5 and R6 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on ?-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: April 26, 2005
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Takashi Tojo, Hidenori Ohki, Nobuyuki Shiraishi, Takahiro Matsuya, Hiroshi Matsuda, Kenji Murano, David Barrett, Takashi Ogino, Keiji Matsuda, Masaharu Ichihara, Norio Hashimoto, Atsushi Kanda, Atsushi Ohigashi
  • Manufacturing method
    Patent number: 6455726
    Abstract: A compound of the following formula (II) and a process for preparing of the compound of the following formula (I) its preparation wherein R1 is carboxy or protected carboxy; R2 is lower alkoxy or higher alkoxy; A1 is a divalent aromatic ring, a divalent heterocyclic group or a divalent cyclo(lower)alkane; and A2 is a divalent aromatic ring, a divalent heterocyclic group or a divalent cyclo(lower)alkane, or a salt thereof. The process comprises, reacting a compound of the formula (III): wherein R1, R2, A1 and A2 are each as defined above or a salt thereof, with an acid ammonium salt to give a compound of the formula (II).
    Type: Grant
    Filed: February 14, 2001
    Date of Patent: September 24, 2002
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masaharu Ichihara, Norio Hashimoto, Atsushi Kanda, Kooji Kagara
  • Production process
    Patent number: 6291680
    Abstract: A compound of formula (1) or a salt thereof: wherein R1 is a carboxy or a protected carboxy; R2 is a lower alkoxy or a higher alkoxy; A1 is a divalent aromatic ring, a divalent heterocyclic group or a divalent cyclo(lower)alkane; and A2 a divalent aromatic ring, a divalent heterocyclic group or a divalent cyclo(lower)alkane; is prepared by reacting a compound of formula (III) or a salt thereof with acid ammonium salt: wherein R1, R2, A1 and A2 are each as defined above; to give a compound of formula (II) or a salt thereof which is further reacted with a salt of hydroxylamine: wherein R1, R2, A1 and A2 are each as defined above.
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: September 18, 2001
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masaharu Ichihara, Norio Hashimoto, Atsushi Kanda, Kooji Kagara
  • Novel manufacturing method
    Publication number: 20010008943
    Abstract: The present invention relates to a novel process for preparing of the compound of the following formula (I)
    Type: Application
    Filed: February 14, 2001
    Publication date: July 19, 2001
    Applicant: FUJISAWA PHARMACEUTICAL CO., LTD.
    Inventors: Masaharu Ichihara, Norio Hashimoto, Atsushi Kanda, Kooji Kagara