Patents by Inventor Masaharu Inui
Masaharu Inui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11046710Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I) or a pharmacologically acceptable salt thereof.Type: GrantFiled: December 22, 2017Date of Patent: June 29, 2021Assignees: Daiichi Sankyo Company, Limited, Sanford Burnham Prebys Medical Discovery InstituteInventors: Shojiro Miyazaki, Masaharu Inui, Yasunobu Kurosaki, Yuko Yamamoto, Masanori Izumi, Kaori Soma, Anthony Pinkerton, Masamichi Kishida
-
Patent number: 11014939Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I) or a pharmacologically acceptable salt thereof.Type: GrantFiled: December 22, 2017Date of Patent: May 25, 2021Assignees: Daiichi Sankyo Company, Limited, Sanford Burnham Prebys Medical Discovery InstituteInventors: Shojiro Miyazaki, Masaharu Inui, Yasunobu Kurosaki, Yuko Yamamoto, Masanori Izumi, Kaori Soma, Anthony Pinkerton, Masamichi Kishida
-
Publication number: 20200087321Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I) or a pharmacologically acceptable salt thereof.Type: ApplicationFiled: December 22, 2017Publication date: March 19, 2020Applicants: DAIICHI SANKYO COMPANY, LIMITED, SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTEInventors: Shojiro Miyazaki, Masaharu Inui, Yasunobu Kurosaki, Yuko Yamamoto, Masanori Izumi, Kaori Soma, Anthony Pinkerton, Masamichi Kishida
-
Patent number: 10221195Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R2 and R3 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R4 and R5 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R6 represents a hydrogen atom or the like, each R7 may be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH?, —C(—R7)?, or —N?, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.Type: GrantFiled: January 18, 2018Date of Patent: March 5, 2019Assignees: Daiichi Sankyo Company, Limited, Sanford Burnham Prebys Medical Discovery InstituteInventors: Shojiro Miyazaki, Yuko Yamamoto, Keisuke Suzuki, Masaharu Inui, Masanori Izumi, Kaori Soma, Anthony Pinkerton, Taeko Shinozaki
-
Publication number: 20180141960Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R2 and R3 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R4 and R5 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R6 represents a hydrogen atom or the like, each R7 may be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH?, —C(—R7)?, or —N?, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.Type: ApplicationFiled: January 18, 2018Publication date: May 24, 2018Applicants: Daiichi Sankyo Company, Limited, Sanford Burnham Prebys Medical Discovery InstituteInventors: Shojiro Miyazaki, Yuko Yamamoto, Keisuke Suzuki, Masaharu Inui, Masanori Izumi, Kaori Soma, Anthony Pinkerton, Taeko Shinozaki
-
Patent number: 9920068Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R2 and R3 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R4 and R5 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R6 represents a hydrogen atom or the like, each R7 may be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH?, —C(—R7)?, or —N?, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.Type: GrantFiled: July 7, 2016Date of Patent: March 20, 2018Assignees: Daiichi Sankyo Company, Limited, Sanford Burnham Prebys Medical Discovery InstituteInventors: Shojiro Miyazaki, Yuko Yamamoto, Keisuke Suzuki, Masaharu Inui, Masanori Izumi, Kaori Soma, Anthony Pinkerton, Taeko Shinozaki
-
Patent number: 9879032Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R2 and R3 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R4 and R5 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R6 represents a hydrogen atom or the like, each R7 may be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH?, —C(—R7)?, or —N?, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.Type: GrantFiled: April 6, 2017Date of Patent: January 30, 2018Assignees: Daiichi Sankyo Company, Limited, Sandford Burnham Prebys Medical Discovery InstituteInventors: Shojiro Miyazaki, Yuko Yamamoto, Keisuke Suzuki, Masaharu Inui, Masanori Izumi, Kaori Soma, Anthony Pinkerton, Taeko Shinozaki
-
Publication number: 20170240562Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R2 and R3 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R4 and R5 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R6 represents a hydrogen atom or the like, each R7 may be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH?, —C(—R7)?, or —N?, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.Type: ApplicationFiled: July 7, 2016Publication date: August 24, 2017Applicants: Daiichi Sankyo Company, Limited, Sanford Burnham Prebys Medical Discovery InstituteInventors: Shojiro Miyazaki, Yuko Yamamoto, Keisuke Suzuki, Masaharu Inui, Masanori Izumi, Kaori Soma, Anthony Pinkerton, Taeko Shinozaki
-
Publication number: 20170210755Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R2 and R3 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R4 and R5 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R6 represents a hydrogen atom or the like, each R7 may be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH?, —C(—R7)?, or —N?, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.Type: ApplicationFiled: April 6, 2017Publication date: July 27, 2017Applicants: Daiichi Sankyo Company, Limited, Sanford Burnham Prebys Medical Discovery InstituteInventors: Shojiro Miyazaki, Yuko Yamamoto, Keisuki Suzuki, Masaharu Inui, Masanori Izumi, Kaori Soma, Anthony Pinkerton, Taeko Shinozaki
-
Patent number: 8927536Abstract: The present invention relates to a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof having an excellent effect of inhibiting 11?-hydroxysteroid dehydrogenase type 1: General formula (I) wherein R1 represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from substituent group A or a heterocyclic group that may be substituted with 1 to 4 group(s) independently selected from substituent group A; R2 independently represents a halogen atom or a C1-C6 alkyl group; n represents an integer of 0 to 2; and substituent group A represents the group consisting of halogen atoms, C1-C6 alkyl groups, and so forth.Type: GrantFiled: October 18, 2013Date of Patent: January 6, 2015Assignee: Daiichi Sankyo Company, LimitedInventors: Makoto Mori, Kunihiko Fujii, Masaharu Inui, Takayuki Baba, Yukari Onishi, Atsushi Aoyagi
-
Publication number: 20140080808Abstract: The present invention relates to a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof having an excellent effect of inhibiting 11?-hydroxysteroid dehydrogenase type 1: General formula (I) wherein R1 represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from substituent group A or a heterocyclic group that may be substituted with 1 to 4 group(s) independently selected from substituent group A; R2 independently represents a halogen atom or a C1-C6 alkyl group; n represents an integer of 0 to 2; and substituent group A represents the group consisting of halogen atoms, C1-C6 alkyl groups, and so forth.Type: ApplicationFiled: October 18, 2013Publication date: March 20, 2014Applicant: Daiichi Sankyo Company, LimitedInventors: Makoto Mori, Kunihiko Fujii, Masaharu Inui, Takayuki Baba, Yukari Onishi, Atsushi Aoyagi
-
Publication number: 20140071197Abstract: There is provided an image forming apparatus including: at least two guide members; a drying section; an ink curing section that illuminates light onto a front surface of the recording medium that has been dried by the drying section and cures the ink; a single liquid coolant circulation device that circulates liquid coolant to respectively formed circulation flow paths between the liquid coolant circulation device and a plurality of cooling targets for which cooling is required due to heat of the drying section or heat of the ink curing section, that cools one of the cooling targets with intermittent circulation of liquid coolant, and that cools another of the cooling targets with continuous circulation of liquid coolant; and an opening and closing portion that opens and closes one of the circulation flow paths to intermittently circulate the liquid coolant of the one cooling target.Type: ApplicationFiled: August 28, 2013Publication date: March 13, 2014Applicant: FUJIFILM CORPORATIONInventors: Yuhei CHIWATA, Masaharu INUI
-
Patent number: 7406272Abstract: An image forming apparatus includes: an image bearing body for bearing a latent image; a plurality of attach/detach sections to each of which a developer container for containing developer used for developing the latent image can be attached; and a container attachment mechanism for allowing a developer container containing developer of a certain color to be attached to any of the plurality of attach/detach sections, and a developer container containing developer of a color other than the certain color to be attached only to a predetermined attach/detach section of among the plurality of attach/detach sections.Type: GrantFiled: July 11, 2005Date of Patent: July 29, 2008Assignee: Seiko Epson CorporationInventors: Kazuhiro Nishiyama, Minoru Kishigami, Katsumi Okamoto, Masaharu Inui
-
Patent number: 7403734Abstract: A developing device includes a housing, a developer bearing roller, a first seal member, a second seal member, a second seal supporting member, and an urging member. The housing has an opening and is adapted to contain a developer. The developer bearing roller is arranged facing the opening and adapted to bear the developer. The first seal member abuts against the developer bearing roller along an axial direction thereof to prevent the developer from spilling. The second seal member abuts against an end, in the axial direction, of the developer bearing roller along a circumferential direction thereof to prevent the developer from spilling. The second seal supporting member supports an end, in a longitudinal direction, of the second seal member, and is attached to the housing such that a boundary section between the second seal member and the second seal supporting member faces the housing.Type: GrantFiled: January 11, 2006Date of Patent: July 22, 2008Assignee: Seiko Epson CorporationInventors: Katsumi Okamoto, Masaharu Inui
-
Publication number: 20060171736Abstract: A developing device includes a housing, a developer bearing roller, a first seal member, a second seal member, a second seal supporting member, and an urging member. The housing has an opening and is adapted to contain a developer. The developer bearing roller is arranged facing the opening and adapted to bear the developer. The first seal member abuts against the developer bearing roller along an axial direction thereof to prevent the developer from spilling. The second seal member abuts against an end, in the axial direction, of the developer bearing roller along a circumferential direction thereof to prevent the developer from spilling. The second seal supporting member supports an end, in a longitudinal direction, of the second seal member, and is attached to the housing such that a boundary section between the second seal member and the second seal supporting member faces the housing.Type: ApplicationFiled: January 11, 2006Publication date: August 3, 2006Inventors: Katsumi Okamoto, Masaharu Inui
-
Publication number: 20060013598Abstract: An image forming apparatus includes: an image bearing body for bearing a latent image; a plurality of attach/detach sections to each of which a developer container for containing developer used for developing the latent image can be attached; and a container attachment mechanism for allowing a developer container containing developer of a certain color to be attached to any of the plurality of attach/detach sections, and a developer container containing developer of a color other than the certain color to be attached only to a predetermined attach/detach section of among the plurality of attach/detach sections.Type: ApplicationFiled: July 11, 2005Publication date: January 19, 2006Inventors: Kazuhiro Nishiyama, Minoru Kishigami, Katsumi Okamoto, Masaharu Inui