Abstract: The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.

Abstract: The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.

Abstract: The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.

Abstract: The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.

Abstract: The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.

Abstract: The present invention provides the compound, 3-[(1S,2S)-1-[5-[(4S)-2,2-Dimethyloxan-4-yl]-2-[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methylindazol-5-yl)-2-oxoimidazol-1-yl]-4-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carbonyl]indol-1-yl]-2-methylcyclopropyl]-4H-1,2,4-oxadiazol-5-one, or a pharmaceutically acceptable salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound.

Abstract: The present invention provides methods for producing peptide compounds. The inventors have found that a cyclic peptide compound can be produced efficiently by linking the N-terminal amino acid residue and the C-terminal amino acid residue of a peptide compound in a solvent containing one or more selected from the group consisting of water-immiscible solvents, water-soluble alkyl nitriles, and water-soluble ethers.

Abstract: The present invention provides the compound, 3-[(1S,2S)-1-[5-[(4S)-2,2-Dimethyloxan-4-yl]-2-(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methylindazol-5-yl)-2-oxoimidazol-1-yl]-4-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carbonyl]indol-1-yl]-2-methylcyclopropyl]-4H-1,2,4-oxadiazol-5-one, or a pharmaceutically acceptable salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound.

Abstract: The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.

Abstract: The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.

Abstract: Disclosed is a gaming machine. The gaming machine is provided with first symbol determining unit for determining a combination of symbols to be displayed in a predetermined area, based on an internal winning combination and second symbol determining unit for determining a combination of symbols to be displayed in an area different from the predetermined area, based on an internal winning combination. Further, the gaming machine is provided with reel stop unit for stopping rotation of the reels, based on the combination of symbols determined by the first symbol determining unit and the combination of symbols determined by the second symbol determining unit and winning determining unit for determining whether a winning is established or not, based on the combination of symbols displayed in the predetermined area, among a plurality of symbols displayed by the stopped reels.

Abstract: Disclosed is a gaming machine. The gaming machine determines a priority attraction-in ranking depending on an internal winning combination and a type of a symbol, for each of the symbols arranged on the reels, compares the priority attraction-in rankings related to each of the symbols ranging from a symbol located at a predetermined position to symbols within a predetermined range, when the stop operation is detected, and stops rotation of the reels when a symbol having the highest priority attraction-in ranking reaches the predetermined position.

Abstract: A display device and operation method thereof for displaying images processed on an image processing apparatus on a horizontally installed, upward facing display screen with the operation method for said display device comprising; a step for specifying the number of screens for display on the display screen, a step for displaying image information on a screen with a predetermined image direction in said display device based on the specified number of screens, a step to change the established display direction, a step to display said screen based on instructions for changing the display direction; and further comprising a step to specify the number of screens for display on said display screen and the direction of said display screen, a step to display an image on the display screen based on the specified number of screens and specified direction of the display screen thus allowing an ideal screen to be provided on a single display device for a plurality of users by changing the direction of the screen along w

Abstract: The present invention makes a variety of improvements on the conventional television receiver to enhance the home communication capability thereof, thereby making the television receiver available as an information terminal apparatus for household use. The novel television receiver that receives a television signal to display a television image on screen comprising: a memory; a microphone through which voice information is entered externally; writing section for writing at least one piece of the voice information entered through the microphone and additional information associated with the at least one piece of voice information into the memory; and a display device for reproducing the at least one piece of voice information stored in the memory and outputting the reproduced voice information through a speaker and displaying the additional information associated with the at least one piece of voice information onto the screen.

Abstract: In a television receiver and a display method thereof, the television receiver includes a video signal processing circuit for receiving a video signal, converting the signal into a video display signal, and outputting the signal therefrom; a video signal storage circuit for receiving the video display signal from the processing circuit, recording the signal for a predetermined period of time, writing the video display signal in an overwriting manner after lapse of the predetermined period of time, and repeating the recording operation at an interval of the predetermined period of time; a switch circuit for receiving the video display signals from the video signal processing and storage circuits, combining the signals with each other in a switching fashion, and outputting a resultant signal therefrom; a control circuit for controlling the video signal storage circuit and switch circuit in response to an indication signal supplied from an external device, combining with each other the video display signals from