Patents by Inventor Masahiko Hirano

Masahiko Hirano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5047846
    Abstract: The present invention relates to an equipment for analyzing the Ca.sup.2+ concentration in the cardiomyocytes, wherein a fluorescent reagent is loaded into the cells to cause intracellular carboxyl groups to be coupled with Ca.sup.2+. The cells are subjected to pulse-excited lights of differing in wavelengths during a vertical blanking period following a predetermined period of time after application of the stimulative signal. The signal causes the cells to generate fluorescent images varying in fluorescence intensity due to the difference in the wavelength of the pulse-excited lights. The resultant images generated are captured by a high-sensitivity television camera and displayed on a video monitor. A plural number of image data are obtained by varying the timing of the stimulating signal with the images stored in image memory.
    Type: Grant
    Filed: August 20, 1990
    Date of Patent: September 10, 1991
    Assignee: Hamamatsu Photonics K.K.
    Inventors: Shigeru Uchiyama, Hideji Fujiwake, Iwayo Nakagawa, Masahiko Hirano, Yoshinori Mizuguchi, Hideshi Oishi, Norikazu Sugiyama