Patents by Inventor Masahiko Kajii

Masahiko Kajii has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfonic acid derivatives of hydroxamic acids and their use as medicinal products
    Patent number: 6989401
    Abstract: The present invention relates to a novel sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof. More particularly, the present invention relates to a sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof, which is useful as an inhibitor of lipopolysaccharides (LPS). In addition, the present invention relates to a novel intermediate compound useful for the synthesis of this sulfonic acid derivative of hydroxamic acid.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: January 24, 2006
    Assignee: Mitsubishi Pharma Corporation
    Inventors: Kazuhiro Maeda, Shuji Sonda, Tadahiro Takemoto, Tomokazu Goto, Fujio Kobayashi, Masahiko Kajii, Naruyasu Komorita, Fumihiro Hirayama
  • Sulfonic acid derivatives of hydroxamic acids and their use as medicinal products
    Publication number: 20030176486
    Abstract: The present invention relates to a novel sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof. More particularly, the present invention relates to a sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof, which is useful as an inhibitor of lipopolysaccharides (LPS). In addition, the present invention relates to a novel intermediate compound useful for the synthesis of this sulfonic acid derivative of hydroxamic acid.
    Type: Application
    Filed: February 14, 2003
    Publication date: September 18, 2003
    Inventors: Kazuhiro Maeda, Shuji Sonda, Tadahiro Takemoto, Tomokazu Goto, Fujio Kobayashi, Masahiko Kajii, Naruyasu Komorita, Fumihiro Hirayama
  • Triazole derivative and pharmaceutical use thereof
    Patent number: 5750545
    Abstract: An agent for the prophylaxis and treatment of immune-related diseases, in particular, immunosuppressant, an agent for the prophylaxis and treatment of allergic diseases, an agent for the prophylaxis and treatment of eosinophil-related diseases and an eosinophilia inhibitor, comprising, as an active ingredient, a series of triazole derivatives of the following formula (I) ##STR1## or the following formula (III) ##STR2## wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. A novel monocyclic or bicyclic triazole derivative. The agent for the prophylaxis and treatment of immune-related diseases, in particular, immunosuppressant, the agent for the prophylaxis and treatment of allergic diseases, the agent for the prophylaxis and treatment of eosinophil-related diseases, the eosinophilia inhibitor and the novel triazole derivative of the present invention all, have superior eosinophilia-inhibitory action and lymphocyte activation-inhibitory action.
    Type: Grant
    Filed: January 23, 1996
    Date of Patent: May 12, 1998
    Assignee: The Green Cross Corporation
    Inventors: Fumihiko Akahoshi, Takehiro Okada, Shinji Takeda, Youichiro Naito, Chikara Fukaya, Shigeki Kuwahara, Masahiko Kajii, Hiroko Nishimura, Masanori Sugiura
  • Substituted or unsubstituted benzhydryl heteroalkyl-substituted aminophenol compounds and pharmaceutical compositions thereof
    Patent number: 5308840
    Abstract: Aminophenol derivatives of the following formula (I) ##STR1## wherein X is hydrogen atom, lower alkyl or a protecting group for phenolic hydroxy, Y is hydrogen atom or lower alkyl, Z is hydrogen atom, lower alkyl, halogen atom or trifluoromethyl, A is hydrogen atom or lower alkyl, t is an integer of 1 to 5, l and m are respectively an integer of 2 to 4, E and W are nitrogen atoms, F is a direct bond or oxygen atom, P and Q are each hydrogen atom, halogen atom, lower alkyl or lower alkoxy, and R.sup.8 is hydrogen atom, hydroxy or a hydroxy-protecting group, and their pharmcologically acceptable salts. Since the aminophenol derivatives (I) of the present invention have excellent antioxidative action and antiinflammatory and antiallergic action in mammalian animals including human, they are extremely useful as pharmaceuticals such as an antiinflammatory or an antiallergic.
    Type: Grant
    Filed: April 6, 1992
    Date of Patent: May 3, 1994
    Assignee: Green Cross Corporation
    Inventors: Naoki Sugiyama, Fumihiko Akaboshi, Haruko Yakumaru, Tomokazu Gotoh, Masanori Sugiura, Shigeki Kuwahara, Masahiko Kajii, Yoshiko Tanaka, Takao Kondoh, Chikara Fukaya