Patents by Inventor Masahiko Kinugawa

Masahiko Kinugawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for producing pyrazoloacridone derivative and synthetic intermediate thereof
    Publication number: 20060217554
    Abstract: (wherein R represents lower alkyl; R1 represents a hydrogen atom, —CH2X or —OC(?O)R3; and R2 represents a hydrogen atom, nitro, halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkoxy, substituted or unsubstituted lower alkylthio or substituted or unsubstituted aryl) The present invention provides a simple industrial process for producing pyrazoloacridone derivatives having an antitumor activity, 1-(2-carboxyphenyl)indazole derivatives, which are useful as synthetic intermediates thereof, or the like; and the like.
    Type: Application
    Filed: April 23, 2004
    Publication date: September 28, 2006
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Nobuaki Tsubakihara, Takeshi Katsuhira, Masahiko Kinugawa, Nobuyuki Kato
  • Process for producing indolocarbazole derivatives
    Patent number: 5585488
    Abstract: In the formulae, R.sup.1, R.sup.2, and R.sup.3 independently represent lower alkyl or aryl, and R.sup.4 represents lower alkyl.The present invention relates to a process for producing an indolocarbazole derivative represented by Formula (II), comprising the acidic treatment of a silylated indolocarbazole derivative represented by Formula (VI).
    Type: Grant
    Filed: February 23, 1996
    Date of Patent: December 17, 1996
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Masahiko Kinugawa, Yoshiaki Masuda, Yukiteru Mimura, Chikara Murakata, Hiromitsu Saito, Takehiro Ogasa, Masaji Kasai, Shinji Tomioka
  • Indole 3-carboxylic acid derivatives
    Patent number: 5344938
    Abstract: An indole derivative represented by formula (I): ##STR1## wherein R.sup.1 is a lower alkoxymethyl group or a formyl group, R.sup.2 is a lower alkyl group, R.sup.3 is a hydrogen atom or a lower alkyl group and R.sup.4 is a hydrogen atom or a lower alkyl group, which is useful as an intermediate for the synthesis of a compound, 5-aziridino-3-hydroxymethyl-l-methyl-2- (1H-indole-4,7-dione)prop-.beta.-ene-.alpha.-ol, which has antitumor activity.
    Type: Grant
    Filed: April 1, 1993
    Date of Patent: September 6, 1994
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Masaji Kasai, Hitoshi Arai, Hiroshi Nishikawa, Takehiro Ogasa, Masahiko Kinugawa, Shinji Tomioka