Abstract: A magnetic storage device includes first and second magnetic layers and a non-magnetic layer, where the non-magnetic layer includes a first oxide layer containing magnesium and oxygen, a second oxide layer containing magnesium and oxygen, a third oxide layer containing zinc and oxygen, a fourth oxide layer containing a first predetermined element and oxygen, and a fifth oxide layer containing a second predetermined element and oxygen, and a crystal structure of an oxide of the first predetermined element and a crystal structure of an oxide of the second predetermined element are each a rock salt structure. The first predetermined element and the second predetermined element each have an oxide formation free energy greater than an oxide formation free energy of zinc, and the oxide of the first predetermined element and the oxide of the second predetermined element each have a bandgap narrower than a bandgap of an oxide of magnesium.

Abstract: According to the present invention, a multilayer tablet showing suppressed layer separation and a production method thereof are provided. A concave portion having a depth of not less than 0.1 mm Ka is formed on at least one surface Sa of the both front and back surfaces (Sa, Sb) of a multilayer tablet. Particularly, a multilayer structure obtained by, in tableting, forming a convex portion for forming the concave portion on at least the upper punch, and preliminarily compressing all layers in the multilayer tablet with the upper punch to form a concave portion having the same shape with a depth of not less than 0.1 mm on the upper surface of all layers, wherein the powder materials of the next layer are protruding into the concave portion, is a preferable embodiment.

Abstract: The present invention can retain the volume of a tablet large without increasing the thickness of the tablet or the like dimension and prevents a plurality of tablets from sticking to each other even if they are subjected to a film-coating or the like treatment, so as to improve the yield. The tablet is a tablet (1) longer in one direction when seen in plan. The tablet (1) has side edges (6) each of which extends in a longitudinal direction and is formed in the shape of a curve projecting outwardly in plan view. The curve has a radius of curvature (R1) set to at least 1.5 times a length (L) of the tablet. This makes a projected area of the tablet (1) in plan view at least 97% with respect to a projected area of a standard elliptical tablet having opposite end portions each of which is formed by a semi-circle having a diameter of a width (W) of the tablet.

Abstract: The present invention provides a solid preparation containing an insulin sensitizer and an active ingredient (except insulin sensitizers), which is useful as a therapeutic drug for diabetes and the like, and which is superior in preparation characteristics such as content uniformity and dissolution property of the insulin sensitizer and the active ingredient (except insulin sensitizers), preparation hardness and the like.

Abstract: According to the present invention, a multilayer tablet showing suppressed layer separation and a production method thereof are provided. A concave portion having a depth of not less than 0.1 mm Ka is formed on at least one surface Sa of the both front and back surfaces (Sa, Sb) of a multilayer tablet. Particularly, a multilayer structure obtained by, in tableting, forming a convex portion for forming the concave portion on at least the upper punch, and preliminarily compressing all layers in the multilayer tablet with the upper punch to form a concave portion having the same shape with a depth of not less than 0.1 mm on the upper surface of all layers, wherein the powder materials of the next layer are protruding into the concave portion, is a preferable embodiment.

Abstract: The present invention provides a solid preparation containing an insulin sensitizer and an active ingredient (except insulin sensitizers), which shows in vivo dissolution behavior of an insulin sensitizer, which is similar to the dissolution behavior of an insulin sensitizer from “a solid preparation containing an insulin sensitizer alone as an active ingredient”. The present invention provides a solid preparation containing (1) a layer containing an insulin sensitizer, and (2) a layer containing (a) an active ingredient (except insulin sensitizers), (b) microcrystalline cellulose having a mean particle size of 5-25 ?m, (c) microcrystalline cellulose having a mean particle size of 30-100 ?m and (d) polyvinylpyrrolidone K-90.

Abstract: The present invention can retain the volume of a tablet large without increasing the thickness of the tablet or the like dimension and prevents a plurality of tablets from sticking to each other even if they are subjected to a film-coating or the like treatment, so as to improve the yield. The tablet is a tablet (1) longer in one direction when seen in plan. The tablet (1) has side edges (6) each of which extends in a longitudinal direction and is formed in the shape of a curve projecting outwardly in plan view. The curve has a radius of curvature (R1) set to at least 1.5 times a length (L) of the tablet. This makes a projected area of the tablet (1) in plan view at least 97% with respect to a projected area of a standard elliptical tablet having opposite end portions each of which is formed by a semi-circle having a diameter of a width (W) of the tablet.

Abstract: The present invention provides a production method of a preparation coated with pioglitazone hydrochloride, which is useful as a therapeutic agent for diabetes and the like, and which is superior in the characteristics of the preparation such as dissolution property of pioglitazone hydrochloride.

Abstract: In a solid pharmaceutical preparation containing 1) a basic medicinal component having an unpleasant taste; 2) a saccharide; 3) a polyanionic polymer; 4) a corrigent; and 5) carboxymethylcellulose, the unpleasant taste of the basic medicinal component having an unpleasant taste can be satisfactorily masked and excellent properties such as quick disintegration, appropriate preparation strength and high storage stability over a long period of time, etc., can be achieved. Further, a quickly disintegrating solid pharmaceutical preparation containing a medicinal component, a sugar alcohol and carboxymethylcellulose has excellent properties such as quick disintegration, appropriate preparation strength, high storage stability over a long period of time, etc.

Abstract: The present invention provides a solid preparation containing an insulin sensitizer and an active ingredient (except insulin sensitizers), which shows in vivo dissolution behavior of an insulin sensitizer, which is similar to the dissolution behavior of an insulin sensitizer from “a solid preparation containing an insulin sensitizer alone as an active ingredient”. The present invention provides a solid preparation containing (1) a layer containing an insulin sensitizer, and (2) a layer containing (a) an active ingredient (except insulin sensitizers), (b) microcrystalline cellulose having a mean particle size of 5-25 ?m, (c) microcrystalline cellulose having a mean particle size of 30-100 ?m and (d) polyvinylpyrrolidone K-90.

Abstract: The present invention provides a production method of a preparation coated with pioglitazone hydrochloride, which is useful as a therapeutic agent for diabetes and the like and superior in the characteristics of the preparation such as dissolution property of pioglitazone hydrochloride and the like.

Abstract: The present invention provides a production method of a preparation coated with pioglitazone hydrochloride, which is useful as a therapeutic agent for diabetes and the like, and which is superior in the characteristics of the preparation such as dissolution property of pioglitazone hydrochloride.

Abstract: The present invention provides a solid preparation containing an insulin sensitizer and an active ingredient (except insulin sensitizers), which is useful as a therapeutic drug for diabetes and the like, and which is superior in preparation characteristics such as content uniformity and dissolution property of the insulin sensitizer and the active ingredient (except insulin sensitizers), preparation hardness and the like.

Abstract: In a solid pharmaceutical preparation containing 1) a basic medicinal component having an unpleasant taste; 2) a saccharide; 3) a polyanionic polymer; 4) a corrigent; and 5) carboxymethylcellulose, the unpleasant taste of the basic medicinal component having an unpleasant taste can be satisfactorily masked and excellent properties such as quick disintegration, appropriate preparation strength and high storage stability over a long period of time, etc., can be achieved. Further, a quickly disintegrating solid pharmaceutical preparation containing a medicinal component, a sugar alcohol and carboxymethylcellulose has excellent properties such as quick disintegration, appropriate preparation strength, high storage stability over a long period of time, etc.

Abstract: The present invention provides a wettable or water-soluble granular agrochemical composition which comprises a guanidine derivative of the formula: wherein R1 represents a homocyclic or heterocyclic group which may optionally be substituted; n is 0 or 1; R2 represents hydrogen or a hydrocarbon group which may optionally be substituted; R3 represents a primary, secondary, or tertiary amino group; X represents an electron attractive group; or a salt thereof, an alkenylsulfonate and a carrier. The agrochemical composition has excellent disintegrability and dispersibility in water.

Abstract: The present invention relates to an aqueous suspension comprising (i) a compound of the formula: or a salt thereof, (ii) a condensate of formaldehyde with an aromatic sulfonic acid or a salt thereof or a polyoxyalkylene allyl phenyl ether sulfate, and (iii) an absorptive water-soluble polymer. The aqueous suspension of the invention can be used with advantage as a stable aqueous suspension of low viscosity providing for excellent delivery from a container, with excellent dispersibility in diluent water and excellent long-term fluidity free from caking due to precipitation of the suspended particles.

Abstract: The present invention provides a wettable or water-soluble granular agrochemical composition which comprises a guanidine derivative of the formula: 1

Abstract: An automatic performance data conversion system having: a storage unit for storing a rule for converting automatic performance data from a first type into a second type, the rule indicating a correspondence between data strings of the automatic performance data of the first and second types; an input unit for inputting the automatic performance data of the fist type; a data converting unit for converting the automatic performance data from the first type into the second type by rearranging a data string contained in the automatic performance data of the first type input by the input unit in accordance with the rule; and an output unit for outputting the automatic performance data of the second type converted by the data converting unit.

Abstract: The key scaling apparatus for an electronic musical instrument having a keyboard includes a memory unit having plural memory areas associated respectively with plural notes or note groups represented by plural keys or key groups of the keyboard; manipulator knobs for producing desired musical tone preparing instruction signals determining the characteristics of the musical tone to be produced; registering means for writing, in those memory areas corresponding to a desired note or note group designated by an operated key, the instruction signals produced by the manipulated knobs; and control means for controlling, when a performance mode is designated, the musical tone to be produced bearing the characteristics as designated by the instruction signals read out from the related memory areas upon operation of a key.

Abstract: An electronic musical instrument with plural pitch data generating functions includes a keyboard, a plurality of tone generating units, a pitch designating unit, a plural pitch data generating unit, and a musical tone generating unit. The keyboard has a plurality of keys. The tone generating units generate at least two tone signals in response to operation of a key among the plural keys. The pitch designating unit designates a pitch of a musical tone to be produced. The plural pitch data generating unit generates at least two pitch data based on the pitch and in accordance with different scale characteristics. The musical tone generating unit generates at least two musical tone signals based on at least two pitch data respectively, so that at least two musical tone signals have the different scale characteristics.