Patents by Inventor Masahiro Furuno
Masahiro Furuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9347919Abstract: The present invention provides a method and apparatus for rapidly extracting the analyte existing in the liquid phase in analyzing an analyte “having a large partition coefficient in gas-liquid equilibrium”, “having a high water solubility”, or “having a low olfactory threshold” by a gas-liquid contact extraction method, and further provides, a method and apparatus for unmanned continuous sample introduction of the analyte to a GC or the like for a long time. In the present invention, using a gas-liquid contact extractor to which a sample liquid is continuously introduced from above and a purge gas from beneath, the analyte in the sample liquid is extracted by gas-liquid contact between the sample liquid and the purge gas. A discharge pipe is connected to the bottom of the gas-liquid contact extractor, the pipe having a liquid sump through which the sample liquid is discharged, while blocking the outflow of the purge gas from the liquid sump.Type: GrantFiled: November 16, 2012Date of Patent: May 24, 2016Assignees: Shimadzu Corporation, GL Sciences IncorporatedInventors: Shinji Fukumoto, Hiroshi Yamauchi, Akira Aono, Manabu Shimomura, Yoshiyuki Takei, Tadashi Mimura, Akira Suzuki, Masahiro Furuno
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Patent number: 9285300Abstract: The present invention provides a monolithic silicone in the form of an aerogel or a xerogel having flexibility and capable of dissolving molecules of a substance. This silicone monolithic body having continuous through passages is synthesized by copolymerizing starting materials of both a bifunctional alkoxysilane and a trifunctional alkoxysilane or tri- or higher functional alkoxysilanes through a sol-gel reaction for forming a Si—O network while causing phase separation.Type: GrantFiled: September 28, 2012Date of Patent: March 15, 2016Assignees: GL SCIENCES INCORPORATED, KYOTO UNIVERSITYInventors: Kazuki Nakanishi, Kazuyoshi Kanamori, Gen Hayase, Masahiro Furuno, Yoshiyuki Takei
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Patent number: 8935941Abstract: To use a monolithic silica body in chromatography with a HPLC column or a GC column and to simplify the use thereof as a separation medium, it is intended to provide a method of cladding a main body of a monolithic adsorbent or separating agent with glass so as to protect the outer surface, and to provide a separation medium prepared by the method. To this end, a monolithic silica body alone is formed by molding, and the molding is coated with a glass body; and then the glass body and the monolithic silica body are fused and integrated at the melting temperature of the glass body at an appropriate pressure. The surface of the resulting monolithic silica body clad with glass is strongly protected by the glass, and the homogeneity of the interior of the monolithic silica body is maintained, and thus uniform flow of a sample solution ensures analytical accuracy.Type: GrantFiled: February 1, 2008Date of Patent: January 20, 2015Assignee: GL Sciences IncorporatedInventors: Shota Miyazaki, Hiroyuki Terashima, Masahiko Nyudo, Masayoshi Ohira, Kei Morisato, Masahiro Furuno
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Publication number: 20140326045Abstract: The present invention provides a method and apparatus for rapidly extracting the analyte existing in the liquid phase in analyzing an analyse “having a large partition coefficient in gas-liquid equilibrium”, “having a high water solubility”, or “having a low olfactory threshold” by a gas-liquid contact extraction method, and further provides, a method and apparatus for unmanned continuous sample introduction of the analyte to a GC or the like for a long time. In the present invention, using a gas-liquid contact extractor to which a sample liquid is continuously introduced from above and a purge gas from beneath, the analyte in the sample liquid is extracted by gas-liquid contact between the sample liquid and the purge gas. A discharge pipe is connected to the bottom of the gas-liquid contact extractor, the pipe having a liquid sump through which the sample liquid is discharged, while blocking the outflow of the purge gas from the liquid sump.Type: ApplicationFiled: November 16, 2012Publication date: November 6, 2014Inventors: Shinji Fukumoto, Hiroshi Yamauchi, Akira Aono, Manabu Shimomura, Yoshiyuki Takei, Tadashi Mimura, Akira Suzuki, Masahiro Furuno
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Publication number: 20140076070Abstract: The present invention provides a monolithic silicone in the form of an aerogel or a xerogel having flexibility and capable of dissolving molecules of a substance. This silicone monolithic body having continuous through passages is synthesized by copolymerizing starting materials of both a bifunctional alkoxysilane and a trifunctional alkoxysilane or tri- or higher functional alkoxysilanes through a sol-gel reaction for forming a Si—O network while causing phase separation.Type: ApplicationFiled: September 28, 2012Publication date: March 20, 2014Inventors: Kazuki Nakanishi, Kazuyoshi Kanamori, Gen Hayase, Masahiro Furuno, Yoshiyuki Takei
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Patent number: 8586350Abstract: A high-purity fragment is obtained by a simple mechanism and method for separating and purifying a nucleic acid, particularly fragment DNA, extremely efficiently and with a high reproducibility, wherein elution with a high-concentration salt is not performed and necessity of elution and purification is eliminated. This mechanism is a mechanism for purifying a nucleic acid, particularly fragment DNA using a monolith structure formed with glass or silica, specifically, an integral porous body having an open structure with pores that communicate the upper end with the lower end, wherein through-pores corresponding to nucleic acid sizes of 35 bp (mer) to 100 Kbp (mer) are provided.Type: GrantFiled: February 12, 2004Date of Patent: November 19, 2013Assignee: GL Sciences IncorporatedInventors: Osuman Toujou, Masayoshi Ohira, Kensuke Okusa, Nobuo Seto, Masahiro Furuno
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Publication number: 20110000279Abstract: To use a monolithic silica body in chromatography with a HPLC column or a GC column and to simplify the use thereof as a separation medium, it is intended to provide a method of cladding a main body of a monolithic adsorbent or separating agent with glass so as to protect the outer surface, and to provide a separation medium prepared by the method. To this end, a monolithic silica body alone is formed by molding, and the molding is coated with a glass body; and then the glass body and the monolithic silica body are fused and integrated at the melting temperature of the glass body at an appropriate pressure. The surface of the resulting monolithic silica body clad with glass is strongly protected by the glass, and the homogeneity of the interior of the monolithic silica body is maintained, and thus uniform flow of a sample solution ensures analytical accuracy.Type: ApplicationFiled: February 1, 2008Publication date: January 6, 2011Applicant: GL SCIENCES INCORPORATEDInventors: Shota Miyazaki, Hiroyuki Terashima, Masahiko Nyudo, Masayoshi Ohira, Kei Morisato, Masahiro Furuno
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Publication number: 20080064115Abstract: The present invention is directed to a system for pre-treatment of a sample to be introduced in a chromatograph, and a method for performing solid-phase extraction of a component present in a sample. The system uses a syringe having a needle being provided with a porous body having a monolithic structure along at least an appropriate length of the needle and across an overall diameter of the needle. The method includes the steps of inserting the needle into the sample, passing the sample through the needle to retain an analyte within the porous body, and desorbtion of the retained analyte from the porous body.Type: ApplicationFiled: April 19, 2002Publication date: March 13, 2008Inventors: Yuka Hiramatsu, Kazuhiko Yamasaki, Masahiro Furuno
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Publication number: 20070181482Abstract: A high-purity fragment is obtained by a simple mechanism and method for separating and purifying a nucleic acid, particularly fragment DNA, extremely efficiently and with a high reproducibility, wherein elution with a high-concentration salt is not performed and necessity of elution and purification is eliminated. This mechanism is a mechanism for purifying a nucleic acid, particularly fragment DNA using a monolith structure formed with glass or silica, specifically, an integral porous body having an open structure with pores that communicate the upper end with the lower end, wherein through-pores corresponding to nucleic acid sizes of 35 bp (mer) to 100 Kbp (mer) are provided.Type: ApplicationFiled: February 12, 2004Publication date: August 9, 2007Applicant: GL SCIENCES INCORPORATEDInventors: Abudogupur Abudokirim, Masayoshi Ohira, Kensuke Okusa, Nobuo Seto, Masahiro Furuno
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Publication number: 20030190757Abstract: For the purpose of extremely simply carrying out a pre-treatment such as sample preparation including extraction or concentration of a component of interest in a short time when performing a chromatographic analysis, it is intended that a column configured such that the inside of a narrow tube is provided with a porous body having open pore structures across the entire diameter of the tube and along an appropriate length of the tube is used and a sample containing a substance to be measured is allowed to pass through the column to retain and concentrate the substance to be measured within pores of the porous body in the column, and it is also intended to provide a method in which the above described process is conducted as a micro trap when carrying out the pre-treatment of the chromatographic analysis and then the removed substances are introduced into analytical means, a method in which a sample is introduced into a separation column after narrowing the sample band when introducing the sample into a liquidType: ApplicationFiled: March 24, 2003Publication date: October 9, 2003Inventors: Masahiro Furuno, Masayoshi Ohira, Noritaka Furushima, Takayuki Hamada, Yuka Hiramatsu, Yukihiro Shintani
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Patent number: 6203597Abstract: To enable the mass injection of a sample in a gas chromatography and prevent occurrence of residue or decomposition of a desired constituent during analysis. The invention calls for providing the injection port with a liner, connecting the column and the liner to a press-fit, evaporating the solvent introduced into the liner, and discharging the evaporated solvent from a discharge port formed at the upper part of the liner.Type: GrantFiled: April 14, 1999Date of Patent: March 20, 2001Assignee: G. L. Scince, Inc.Inventors: Ryoichi Sasano, Kazuhiko Yamazaki, Masahiro Furuno
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Patent number: 5442949Abstract: In a gas scavenging unit for gas chromatography analysis of gas generated in a thermal analyzer, the thermal analyser is equipped with a gas scavenging unit for scavenging gas generated in the thermal analyzer without usage of a carrier gas and no influence of a switching valve exists in the case of multi-stage sampling. For scavenging, there can be provided multiple sampling flow paths each have an aperture placed between the sample and the carrier gas outlet of the thermal analyzer, a flow regulator, a flow path switching valve, and a suction unit which is connected to the switching valve. The gas generated in the thermal analyzer is suctioned by the suction unit through a sampling flow path which is changed with the flow path switching valve. The appropriate volume of gas is scavenged to the GC analysis without any influence of the flow (rate) of the carrier gas even when the scavenging is done through switching to multiple scavengers.Type: GrantFiled: February 24, 1994Date of Patent: August 22, 1995Assignees: Seiko Instruments Inc., GL Science Inc.Inventors: Ryoichi Kinoshita, Yoshiyuki Takei, Yoshizumi Takigawa, Masahiro Furuno