Abstract: To make it possible to grasp a biological condition, in particular, a condition ascribable to the movement of the heart. According to the embodiments, it is possible to find a boundary frequency between cardiac apex beat and heart sound. This makes it possible to find not only heart sound, but also cardiac apex beat, from a biological signal which is a collection of biological sound and in-vivo vibration. The boundary frequency is represented by a quadratic function of heart rate, and the use of correlation data based on the quadratic function makes it possible to find heart rate or a boundary frequency in real time. As a result, for example, if heart rate is known, the level of a boundary frequency is known. This facilitates inferring a health condition, for example, whether or not the heart is under stress, from a broader viewpoint than conventionally.

Abstract: Disclosed herein are methods for delivering a composition comprising an adeno-associated virus (AAV) to one or more pancreatic cells in a subject. Also disclosed are adeno-associated viral vectors for use in these methods.

Abstract: There are provided a biological signal measurement device capable of obtaining a variety of biological information and applicable also to medical fields and the like, a biological state inference device, and a biological state inference system using these. The biological signal measurement device 1 of the present invention includes three biological signal detection units, namely, a left upper part biological signal detection unit 11, a right upper part biological signal detection unit 12, and a lower part biological signal detection unit 13. The biological state inference device 1 is capable of obtaining a highly precise inference-use processed waveform from which electrical noise has been removed, by using an appropriate combination of time-series data obtained from the three biological signal detection units 11 to 13.

Abstract: Provided is a packaging bag (1) in which a broken piece can be separated easily at the time of unsealing. In a packaging bag (1) in which unsealing is conducted from a sealed part (2) on an unsealing start side to a sealed part (4) on an unsealing terminal side via an accommodation part (3), an easily-openable part (10) is provided at the sealed part (2) on the unsealing start side, and an inner edge of the sealed part (4) on the unsealing terminal side is an inner edge inclined part (5u) that crosses an unsealing virtual straight line (12) linearly drawn in an unsealing direction from the easily-openable part (10) to the sealed part (4) on the unsealing terminal side via the accommodation part (3), and is inclined relative to the unsealing virtual straight line (12).

Abstract: Provided is a packaging bag (1) in which a broken piece can be separated easily at the time of unsealing. In a packaging bag (1) in which unsealing is conducted from a sealed part (2) on an unsealing start side to a sealed part (4) on an unsealing terminal side via an accommodation part (3), an easily-openable part (10) is provided at the sealed part (2) on the unsealing start side, and an inner edge of the sealed part (4) on the unsealing terminal side is an inner edge inclined part (5u) that crosses an unsealing virtual straight line (12) linearly drawn in an unsealing direction from the easily-openable part (10) to the sealed part (4) on the unsealing terminal side via the accommodation part (3), and is inclined relative to the unsealing virtual straight line (12).