Abstract: There is disclosed novel fused thiophene derivatives as prophylactic and therapeutic drugs for bone or articular diseases, industrially advantageous processes for production thereof, and novel production intermediates.

Abstract: Provided is a rocking member apparatus comprising torsion springs, a rocking member axially supported by the torsion spring, and a supporting substrate, the rocking member being rockable about the torsion spring, wherein a hard magnetic member is provided on one surface of the rocking member, a coil and a soft magnetic member, which are arranged so as to be spaced apart from the rocking member, the coil and the soft magnetic member are arranged at different positions in a direction vertical to the one surface, and the hard magnetic member is arranged at a position which is the same position as the soft magnetic member and the one surface in a direction vertical thereto, or a position which is on the side where the coil is arranged as seen from the soft magnetic member, whereby the apparatus can be made small and lightweight and allows increased deflection angle, high-speed scanning, and reduced power consumption.

Abstract: The invention provides chromone derivatives of the following general formula, a process for preparing such chromone derivatives and a prophylactic and therapeutic agent comprising such chromone derivatives for bone diseases and chondropathy: wherein the ring A is an optionally substituted benzene ring; R1 is an optionally substituted non-aromatic heterocyclic group; R2 is a hydrogen atom or hydrocarbon group; R3 is a hydrogen atom, hydrocarbon group or halogen; n is an integer of 0-3; or a salt thereof.

Abstract: A magnetic detection element of the present invention for detecting a strength of an external magnetic field, comprises a magnetic thin film formed on a single non-magnetic substrate, a circuit that applies a high-frequency current to the magnetic thin film, and a spiral type planar coil that is stacked on the magnetic thin film through an insulating layer, wherein the magnetic thin film is formed in a longitudinal shape and magnetic anisotropy is given so that direction of easy magnetization axis is orthogonal to a longitudinal direction of the longitudinal shape.

Abstract: A method for transdermal administration of parathyroid hormone by iontophoresis, which comprises applying electric current at least 2 times a day, which method is repeated one to four times each week, or an apparatus for the iontophoresis can be widely applied for not only the prevention or treatment of osteoporosis but also for general bone diseases which require promotion of bone morphogenesis, for example, treatment of ordinary fractures. The method of the present invention produces excellent pharmacological effects such as few side effects and a high bioavailability in long term administration for the prevention and treatment of bone diseases.

Abstract: In a magnetic impedance element in which an element body is formed of a magnetic thin film formed on a non-magnetic substrate, and when a high-frequency current is supplied to the magnetic thin film, an impedance between both ends of the magnetic thin film changes in accordance with an external magnetic field, the magnetic thin film is formed in a slender zigzag pattern obtained by folding a straight line in parallel several times, and an easy axis of magnetization of the magnetic thin film is so set as to be directed along the longitudinal direction of the pattern. Also, assuming that a thickness of the magnetic thin film is T, a line width of the pattern is W, and a length of the pattern is L, T is in a range of 1 to 5 &mgr;m, and L/(W×T) is in a range of 10 to 400×106 m−1.

Abstract: A first portion of a perimeter of an outer circumferential portion of a tire is magnetized with a first polarity along the steel belt in one circumferential direction less than 360° and a second portion of the perimeter is magnetized with a second polarity in an opposite circumferential direction. The magnetic field generated by the magnetized steel belt is detected by two magnetic detection elements, which are set so that the magnetic field detection directions of the two magnetic detection elements are parallel to the side surface of the tire, and the two elements are juxtaposed in a direction perpendicular to the side surface of the tire.

Abstract: An electric current sensor comprises a pair of magnetic detectors arranged near a signal line flowing an electric current to be detected and a differential amplifier for differentially amplifying two signals obtained by the paired magnetic detectors detecting a magnetic field from the electric current flowing through the signal line and outputting a detection signal for the detected electric current. The paired magnetic detectors are arranged adjacent to each other along a first straight line and as sandwiching therebetween a second straight line. The first straight line is perpendicular to but spaced from the signal line and the second straight line crosses perpendicularly to both the first straight line and the signal line. The paired magnetic detectors have the same magnetic field detecting direction, which may be parallel or inclined relative to the second straight line.

Abstract: In a magnetic detecting element utilizing a magnetic impedance effect, a high-permeability magnetic film is formed on a non-magnetic substrate and has magnetic anisotropy in a predetermined direction in the plane of the magnetic film. A high-frequency current is applied across two point in a direction perpendicular to the direction of the magnetic anisotropy, and a change in impedance generated between the two points is converted into an electric signal to obtain an output.

Abstract: A method for transdermal administration of parathyroid hormone by iontophoresis, which comprises applying electric current at least 2 times a day, which method is repeated one to four times each week, or an apparatus for the iontophoresis can be widely applied for not only the prevention or treatment of osteoporosis but also for general bone diseases which require promotion of bone morphogenesis, for example, treatment of ordinary fractures.

Abstract: A magnetic sensor for detecting magnetic fields deriving from a magnetic body to detect any magnetic body on a non-magnetic body by moving relative to the non-magnetic body in prescribed relative moving directions along the surface of the non-magnetic body includes a magnetizing magnet in which a line connecting the N and S poles thereof is a direction substantially orthogonal to, and of which one pole is arranged either in contact with or in proximity to, the surface of the non-magnetic body; and a magnetism detecting element having two magnetic detectors arranged along a magnetic field detecting direction, the magnetic field detecting direction being orthogonal to the relative moving directions in a surface parallel to the surface of the non-magnetic body, wherein the magnetic body is magnetized by the magnetizing magnet along with the movement relative to the non-magnetic body, and magnetic fields according to the quantity of the magnetized part of the magnetic body are differentially detected by the two m

Abstract: A tire (12) used includes a steel belt in its outer circumferential portion. A magnetic sensor (14) including a pair of magnetic detection elements (18A, 18B), which are arranged so that their magnetic detection directions become parallel to each other or series each other, is set in the vicinity of a rear tire (12) in a trunk room of a vehicle (10). Changes in magnetic field upon revolution of the tire (12) are differentially detected by the magnetic detection elements (18A, 18B), and the revolution of the tire (12) is detected on the basis of the differentially detected output waveform. Among a plurality of peaks present in the differentially detected output waveform, a peak, the potential difference from the immediately preceding peak of which is equal to or larger than a predetermined threshold value, is detected as an effective peak, which is effective for tire revolution detection, and the revolution speed of the tire is calculated by detecting the number of effective peaks.

Abstract: A tire (12) used includes a steel belt in its outer circumferential portion. A magnetic sensor (14) including a pair of magnetic detection elements (18A, 18B), which are arranged so that their magnetic detection directions become parallel to each other or series each other, is set in the vicinity of a rear tire (12) in a trunk room of a vehicle (10). Changes in magnetic field upon revolution of the tire (12) are differentially detected by the magnetic detection elements (18A, 18B), and the revolution of the tire (12) is detected on the basis of the differentially detected output waveform. Among a plurality of peaks present in the differentially detected output waveform, a peak, the potential difference from the immediately preceding peak of which is equal to or larger than a predetermined threshold value, is detected as an effective peak, which is effective for tire revolution detection, and the revolution speed of the tire is calculated by detecting the number of effective peaks.

Abstract: A magnetization magnet (11) is brought into contact with or close to the outer circumferential surface of a tire (12) that has a steel belt in its outer circumferential portion, and is relatively moved along the circumferential direction of the tire (12) so that the magnetic field generated by the magnetization magnet (11) runs in the circumferential direction of the tire. (12), thereby magnetizing the tire (12). The entire perimeter of the outer circumferential portion of the tire (12) is continuously magnetized in one direction along the circumferential direction. After the polarities of the magnetization magnet (11) are inverted with respect to the circumferential direction of the tire (12), an angle range smaller than 360.degree. on the outer circumferential portion of the tire is continuously re-magnetized in a direction opposite to the one direction.

Abstract: A magnetic card provided with a recording track in which a magnetic portion is disposed in an intermittent pattern corresponding to a digital signal is employed, and the magnetic portion of the recording track is magnetized immediately before information is read from the magnetic card. Then, a magnetism detecting device is made to relatively move with respect to the recording track to detect a magnetic flux arising from the magnetic portion, thereby reading the information represented by the digital signal.

Abstract: A coin identification device for detecting a change in magnetic field due to eddy currents produced in a coin and identifying the coin on the basis of the detected change includes a path along which the coin moves, a sensor including two coils juxtaposed at a predetermined interval along the path and disposed such that a central axis of each of the two coils is in line with a direction perpendicular to an obverse or reverse of the coin moving along the path, and two magnetic impedance elements disposed respectively within the two coils to extend along the central axes of the two coils, and an identification circuit for outputting an identification signal for identification of the coin by differentially amplifying outputs of the two magnetic impedance elements.

Abstract: A magnetism detecting device of a magnetic impedance effect type includes a high-permeability magnetic film formed on a side of an approximately rectangular parallelepipedic, non-magnetic substrate. The high-permeability magnetic film is formed as a folded pattern having end portions extending in opposite directions and at least one folded portion disposed between the end portions, a longitudinal direction of the high-permeability magnetic film being parallel to a magnetic-field detecting direction. The high-permeability magnetic film is imparted magnetic anisotropy so that a direction of an axis of easy magnification of the high-permeability film is perpendicular to the longitudinal direction of the high-permeability magnetic film in a film plane thereof. Conductive films are formed at both ends of the high-permeability magnetic film as terminals.

Abstract: A magnetic head for reproducing digital magnetic recording information using a MI head, which is a magnetic detection element utilizing magnetic impedance effect, the magnetic recording medium 10 is magnetized alternatively, in the opposite direction along a relative movement direction relative to the magnetic head, the boundary 11 of magnetization is a straight line normal to the relative movement direction, and the MI element 12 opposes in parallel with the surface of the recording medium 10. In a surface in parallel with the surface of the element 12, the MI element is positioned so that its longitudinal direction is inclined by an angle .theta. relative to the direction of the boundary 11 of magnetization. A high frequency current is applied via terminals 13A and 13B to obtain a reproduced signal through the magnetic impedance effect.

Abstract: In a magnetic detecting element utilizing a magnetic impedance effect, a high-permeability magnetic film is formed on a non-magnetic substrate and has magnetic anisotropy in a predetermined direction in the plane of the magnetic film. A high-frequency current is applied across two points in a direction perpendicular to the direction of the magnetic anisotropy, and a change in impedance generated between the two points is converted into an electric signal to obtain an output.

Abstract: An alternating bias current is made to flow through a coil wound around an MI device incorporated in an oscillation circuit, and an alternating-current bias magnetic field is applied to the MI device. An amplitude-modulated waveform corresponding to peaks which alternate between two different heights is provided at the output of the oscillation circuit in accordance with an impedance variation in the MI device according to an external magnetic field and the alternating-current bias magnetic field. The difference in height between the peaks corresponds to the strength of the external magnetic field. The output of the oscillation circuit is envelope-detected by an envelope detecting circuit, and an alternating-current component from which a direct-current component is eliminated is inputted to a comparator. The comparator provides an output signal having a digital waveform pulse-width modulated according to the difference in height between the peaks.