Abstract: A condensed heterocyclic compound has a sepiapterin reductase inhibitory action and is particularly useful for treatment of a pain. The condensed heterocyclic compound represented by Formula (I) below (R1 represents a hydrocarbon group or the like; R2 and R3 represent a hydrogen atom or the like; R4, X, and Y represent defined substituents), a tautomer or a pharmaceutically acceptable salt of the compound, or a solvate of any of these.

Abstract: In a cooling device for a high temperature pipe, a high temperature pipe is efficiently cooled, and cooling performance is improved. A cooling device (10) for a high temperature pipe that cools a surface to be cooled (104) of a pipe (100) as a high temperature pipe includes: a cooling medium supply header (11) that is disposed so as not to shield heat dissipation by radiation from the surface to be cooled (104) to the periphery, and allows a cooling medium to flow out toward the surface to be cooled (104); and a cooling medium supply device (12) that supplies the cooling medium to the cooling medium supply header (11).