Patents by Inventor Masahiro Maruyama

Masahiro Maruyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220056020
    Abstract: The present invention provides a compound represented by the following formula (I), a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein: R1 and R2 are each separately selected from the group consisting of hydrogen, alkyl, alkenyl, acyl, and hydroxyalkyl; R3 is hydrogen or halogen; ring A is a benzene ring or a pyridine ring; ring B is selected from the group consisting of the following formulas (i), (ii), (iii), and (iv): in the formula (ii), Ra is alkyl; R4 and R5 are each separately selected from the group consisting of hydrogen, hydroxy, alkoxy, haloalkoxy, halohydroxyalkoxy, and aminoalkyl; and represents a double bond or a triple bond. The above compound can be used as a molecular probe for imaging tau proteins that accumulate in the brain.
    Type: Application
    Filed: September 16, 2021
    Publication date: February 24, 2022
    Inventors: Makoto HIGUCHI, Tetsuya SUHARA, Masahiro MARUYAMA, Meiei CHO, Hitoshi SHIMADA
  • Publication number: 20200262829
    Abstract: The present invention provides a compound represented by the following formula (I), a pharmaceutically acceptable salt thereof, or a solvate thereof. wherein: R1 and R2 are each separately selected from the group consisting of hydrogen, alkyl, alkenyl, acyl, and hydroxyalkyl; R3 is hydrogen or halogen; ring A is a benzene ring or a pyridine ring; ring B is selected from the group consisting of the following formulas (i), (ii), (iii), and (iv): in the formula (ii), Ra is alkyl; R4 and R5 are each separately selected from the group consisting of hydrogen, hydroxy, alkoxy, haloalkoxy, halohydroxyalkoxy, and aminoalkyl; and [Formula 3] represents a double bond or a triple bond. The above compound can be used as a molecular probe for imaging tau proteins that accumulate in the brain.
    Type: Application
    Filed: February 21, 2020
    Publication date: August 20, 2020
    Inventors: Makoto Higuchi, Tetsuya Suhara, Masahiro Maruyama, Meiei Cho, Hitoshi Shimada
  • Patent number: 10704603
    Abstract: A cage assembly is moved in the axial direction to approach an inner ring from a small rib portion side. An inner ring assembly is constituted by causing tapered rollers of the cage assembly to climb over a small rib portion to be fitted on an inner raceway surface, and then is assembled to an outer ring. In this method, a jig is provided adjacent to the small rib portion. The jig includes recessed grooves that are formed in the outer peripheral portion of the jig and that enable contact of the respective tapered rollers. Each recessed groove has a recessed arcuate shape in cross section. The tapered rollers of the cage assembly are caused to slide radially outward along the recessed grooves, so that the diameter of cage is increased. Accordingly, the tapered rollers climb over the small rib portion to be fitted on the inner raceway surface.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: July 7, 2020
    Assignee: JTEKT CORPORATION
    Inventors: Masahiro Maruyama, Akiyuki Suzuki, Ryo Shiina
  • Patent number: 10604516
    Abstract: The present invention provides a compound represented by the following formula (I), a pharmaceutically acceptable salt thereof, or a solvate thereof. wherein: R1 and R2 are each separately selected from the group consisting of hydrogen, alkyl, alkenyl, acyl, and hydroxyalkyl; R3 is hydrogen or halogen; ring A is a benzene ring or a pyridine ring; ring B is selected from the group consisting of the following formulas (i), (ii), (iii), and (iv): in the formula (ii), Ra is alkyl; R4 and R5 are each separately selected from the group consisting of hydrogen, hydroxy, alkoxy, haloalkoxy, halohydroxyalkoxy, and aminoalkyl; and ??[Formula 3] represents a double bond or a triple bond. The above compound can be used as a molecular probe for imaging tau proteins that accumulate in the brain.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: March 31, 2020
    Assignee: National Institutes for Quantum and Radiological Science and Technology
    Inventors: Makoto Higuchi, Tetsuya Suhara, Masahiro Maruyama, Meiei Cho, Hitoshi Shimada
  • Publication number: 20180252268
    Abstract: A cage assembly is moved in the axial direction to approach an inner ring from a small rib portion side. An inner ring assembly is constituted by causing tapered rollers of the cage assembly to climb over a small rib portion to be fitted on an inner raceway surface, and then is assembled to an outer ring. In this method, a jig is provided adjacent to the small rib portion. The jig includes recessed grooves that are formed in the outer peripheral portion of the jig and that enable contact of the respective tapered rollers. Each recessed groove has a recessed arcuate shape in cross section. The tapered rollers of the cage assembly are caused to slide radially outward along the recessed grooves, so that the diameter of cage is increased. Accordingly, the tapered rollers climb over the small rib portion to be fitted on the inner raceway surface.
    Type: Application
    Filed: February 20, 2018
    Publication date: September 6, 2018
    Applicant: JTEKT CORPORATION
    Inventors: Masahiro MARUYAMA, Akiyuki SUZUKI, Ryo SHIINA
  • Publication number: 20150239878
    Abstract: The present invention provides a compound represented by the following formula (I), a pharmaceutically acceptable salt thereof, or a solvate thereof. wherein: R1 and R2 are each separately selected from the group consisting of hydrogen, alkyl, alkenyl, acyl, and hydroxyalkyl; R3 is hydrogen or halogen; ring A is a benzene ring or a pyridine ring; ring B is selected from the group consisting of the following formulas (i), (ii), (iii), and (iv): in the formula (ii), Ra is alkyl; R4 and R5 are each separately selected from the group consisting of hydrogen, hydroxy, alkoxy, haloalkoxy, halohydroxyalkoxy, and aminoalkyl; and ??[Formula 3] represents a double bond or a triple bond. The above compound can be used as a molecular probe for imaging tau proteins that accumulate in the brain.
    Type: Application
    Filed: December 21, 2012
    Publication date: August 27, 2015
    Inventors: Makoto Higuchi, Tetsuya Suhara, Masahiro Maruyama, Meiei Cho, Hitoshi Shimada
  • Publication number: 20110190492
    Abstract: The invention provides a probe compound useful for early diagnosis of conformation disease, a composition and a kit comprising it for diagnosis for conformation disease, and a medical composition for treatment and/or prevention of conformation disease.
    Type: Application
    Filed: April 14, 2011
    Publication date: August 4, 2011
    Applicant: TOHOKU UNIVERSITY
    Inventors: Yukitsuka KUDO, Hiroyuki ARAI, Nobuyuki OKAMURA, Masahiro MARUYAMA, Syozo FURUMOTO, Katsumi DOH-URA
  • Publication number: 20090185975
    Abstract: The invention provides a probe compound useful for early diagnosis of conformation disease, a composition and a kit comprising it for diagnosis for conformation disease, and a medical composition for treatment and/or prevention of conformation disease.
    Type: Application
    Filed: December 25, 2006
    Publication date: July 23, 2009
    Applicant: TOHOKU UNIVERSITY
    Inventors: Yukitsuka Kudo, Hiroyuki Arai, Nobuyuki Okamura, Masahiro Maruyama, Syozo Furumoto, Katsumi Doh-Ura
  • Publication number: 20090129105
    Abstract: A vehicle is equipped with a slide door, a seat provided near an ingress-egress opening, and an ingress-action detector to detect a passenger's ingress action through the ingress-egress opening. The vehicle is further equipped with an illumination device which comprises lower illuminators which are configured to illuminate lower areas which are located below a beltline of the vehicle such that a passenger's upper body is not illuminated, vehicle-inside upper illuminators which are configured to illuminate an upper-specified area in the vehicle compartment which is located above the beltline, and an illumination controller to control the illuminators. When the ingress action is detected by the ingress-action detector, the illumination controller prohibits the illuminations of the illuminators and starts the illuminations of the illuminators.
    Type: Application
    Filed: November 18, 2008
    Publication date: May 21, 2009
    Applicant: MAZDA MOTOR CORPORATION
    Inventors: Hirotaka KUSU, Harunori NAGAO, Kou NIIDA, Masahiro MARUYAMA, Takayuki SAGAHARA, Masayoshi SANNOMIYA, Yubing BAI, Yoko Daikokuya, Kazuhiro SAEKI, Yuzo SATO, Kazuto KATAYAMA
  • Patent number: 6609745
    Abstract: A seat device of a vehicle including a substantially flat floor surface substantially extending across a full cabin space of the vehicle, front row seats, center row seats and a rear row seat disposed in a longitudinal direction of the vehicle on the floor surface, a seat storage pan extending rearward the rear row seat and downward a level of the floor surface, the front row seats being disposed with a space, the center row seats including a plurality of seats in which at least one of the seats is movable in a lateral direction of the vehicle. When the rear row seat is received in the seat storage pan, a substantially flat and continuous surface of a substantially same level as the floor surface is formed rearward the center row seats to a rear end of the cabin space with a substantially full width of the cabin space.
    Type: Grant
    Filed: June 13, 2002
    Date of Patent: August 26, 2003
    Assignee: Mazda Motor Corporation
    Inventors: Tamio Miyahara, Kazuhiro Matsuhashi, Masahiro Maruyama, Yasukazu Watanabe, Akira Itoh
  • Publication number: 20020153740
    Abstract: A seat device of a vehicle including a substantially flat floor surface substantially extending across a full cabin space of the vehicle, front row seats, center row seats and a rear row seat disposed in a longitudinal direction of the vehicle on the floor surface, a seat storage pan extending rearward the rear row seat and downward a level of the floor surface, the front row seats being disposed with a space, the center row seats including a plurality of seats in which at least one of the seats is movable in a lateral direction of the vehicle. When the rear row seat is received in the seat storage pan, a substantially flat and continuous surface of a substantially same level as the floor surface is formed rearward the center row seats to a rear end of the cabin space with a substantially full width of the cabin space.
    Type: Application
    Filed: June 13, 2002
    Publication date: October 24, 2002
    Inventors: Tamio Miyahara, Kazuhiro Matsuhashi, Masahiro Maruyama, Yasukazu Watanabe, Akira Itoh
  • Patent number: 6435590
    Abstract: A seat device of a vehicle including a substantially flat floor surface substantially extending across a full cabin space of the vehicle, front row seats, center row seats and a rear row seat disposed in a longitudinal direction of the vehicle on the floor surface, a seat storage pan extending rearward the rear row seat and downward a level of the floor surface, the front row seats being disposed with a space, the center row seats including a plurality of seats in which at least one of the seats is movable in a lateral direction of the vehicle. When the rear row seat is received in the seat storage pan, a substantially flat and continuous surface of a substantially same level as the floor surface is formed rearward the center row seats to a rear end of the cabin space with a substantially full width of the cabin space.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: August 20, 2002
    Assignee: Mazda Motor Corporation
    Inventors: Tamio Miyahara, Kazuhiro Matsuhashi, Masahiro Maruyama, Yasukazu Watanabe, Akira Itoh
  • Publication number: 20020011737
    Abstract: A seat device of a vehicle including a substantially flat floor surface substantially extending across a full cabin space of the vehicle, front row seats, center row seats and a rear row seat disposed in a longitudinal direction of the vehicle on the floor surface, a seat storage pan extending rearward the rear row seat and downward a level of the floor surface, the front row seats being disposed with a space, the center row seats including a plurality of seats in which at least one of the seats is movable in a lateral direction of the vehicle. When the rear row seat is received in the seat storage pan, a substantially flat and continuous surface of a substantially same level as the floor surface is formed rearward the center row seats to a rear end of the cabin space with a substantially full width of the cabin space.
    Type: Application
    Filed: September 18, 2001
    Publication date: January 31, 2002
    Inventors: Tamio Miyahara, Kazuhiro Matsuhashi, Masahiro Maruyama, Yasukazu Watanabe, Akira Itoh
  • Patent number: 6129405
    Abstract: A seat device of a vehicle including a substantially flat floor surface substantially extending across a full cabin space of the vehicle, front row seats, center row seats and a rear row seat disposed in a longitudinal direction of the vehicle on the floor surface, a seat storage pan extending rearward the rear row seat and downward a level of the floor surface, the front row seats being disposed with a space, the center row seats including a plurality of seats in which at least one of the seats is movable in a lateral direction of the vehicle. When the rear row seat is received in the seat storage pan, a substantially flat and continuous surface of a substantially same level as the floor surface is formed rearward the center row seats to a rear end of the cabin space with a substantially full width of the cabin space.
    Type: Grant
    Filed: March 1, 1999
    Date of Patent: October 10, 2000
    Assignee: Mazda Motor Corporation
    Inventors: Tamio Miyahara, Kazuhiro Matsuhashi, Masahiro Maruyama, Yasukazu Watanabe, Akira Ito
  • Patent number: 4868977
    Abstract: The present invention relates to improvement in a working apparatus, such as an electronic part automatic-mounting apparatus comprising carriers for holding and moving works on a working line and a work head for applying a predetermined operation at a predetermined position on the work moved by the carriers, to a work station. The apparatus also includes: head driving means for moving the work head in directions (for examples, a Y direction) different from the moving direction of the work (for example, an X direction) and carrier driving means for moving the carriers along the working line sequentially from a work feed position to a work station, onto a work discharge position and then moving or restoring the work back to the work feed position (7). The carrier driving means also position the point of operation on the work in the moving direction fo the work at the work station.
    Type: Grant
    Filed: September 24, 1987
    Date of Patent: September 26, 1989
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Masahiro Maruyama, Kanji Hata, Eiji Itemadani, Yoshihisa Uchida
  • Patent number: 4857752
    Abstract: A part such as electronic parts is irradiated by diffused light and a silhouette of the parts is sensed by an image sensor, and plural optical systems are placed between the parts and the image sensor, and thereby the silhouette of the parts is divided into plural portions, moreover a shutter having plural openings is provided between the image sensor and the optical system to select one of the plural optical systems; thus one of respective silhouettes of the plural portions is sensed by the image sensor, and the portions are sensed in turn by shifting the shutter.
    Type: Grant
    Filed: March 25, 1988
    Date of Patent: August 15, 1989
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Kanji Hata, Masahiro Maruyama, Eiji Itemadani
  • Patent number: 4815913
    Abstract: An electronic component mounting device for mounting an electronic component onto a circuit-board, is provided with an intermittently rotatable rotary frame, a plurality of elevating members disposed around and along the periphery of the rotary frame at regular intervals so as to be free to move up and down, a plurality of electronic component holding members respectively securely mounted on the elevating members each to hold one electronic component at a time, an index unit for controlling the intermittent rotation of the rotary frame by way of a shaft, a cam mechanism for moving the elevating members up and down with the rotation of the rotary frame, and an operating member for moving any one of the electronic component holding members up and down.
    Type: Grant
    Filed: March 17, 1988
    Date of Patent: March 28, 1989
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Kanji Hata, Masahiro Maruyama, Eiji Itemadani
  • Patent number: 4809430
    Abstract: In the mounting of an electronic component, a holding member is rotated by a predetermined angle prior to actual holding of the electronic parts, thereby to detect a center of the holding member from at least two positions of the rotation angle, and the rotation center of the holding member is found by a calculation based on the detected center of the holding member. The position of the electronic parts against a circuit board then is corrected on the basis of a deviation between the position of the rotation center and the center of the holding member.
    Type: Grant
    Filed: June 11, 1987
    Date of Patent: March 7, 1989
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Masahiro Maruyama, Kanji Hata, Eiji Itemadani, Masao Iritani
  • Patent number: 4807356
    Abstract: The present invention is a part mounting device for mounting chip parts on a substrate, comprising a linear motor having a columnar yoke with upper and lower ends thereof pivotably supported on the device, permanent magnets disposed in the vicinity of the columnar yoke and forming with the columnar yoke a magnetic circuit, and a bobbin disposed in the vicinity of the columnar yoke and slidable in the columnar direction of the yoke;a chip part holder fixedly secured to the bobbin and having a vacuum nozzle for picking up and holding chip parts;a mechanism connected to said linear motor for controlling the driving of the linear motor for driving the part holder rapidly for moving chip parts quickly from a first position remote from the position of the substrate on which the chip parts are to be mounted to a third position just before the chip parts are on the substrate and then driving the part holder slowly to move the chip parts from the third position to a second position where the chip parts are on the subs
    Type: Grant
    Filed: January 7, 1987
    Date of Patent: February 28, 1989
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Masahiro Maruyama, Kazuhiro Mori, Eiji Itemadani, Mikio Hasegawa
  • Patent number: RE39101
    Abstract: A seat device of a vehicle including a substantially flat floor surface substantially extending across a full cabin space of the vehicle, front row seats, center row seats and a rear row seat disposed in a longitudinal direction of the vehicle on the floor surface, a seat storage pan extending rearward the rear row seat and downward a level of the floor surface, the front row seats being disposed with a space, the center row seats including a plurality of seats in which at least one of the seats is movable in a lateral direction of the vehicle. When the rear row seat is received in the seat storage pan, a substantially flat and continuous surface of a substantially same level as the floor surface is formed rearward the center row seats to a rear end of the cabin space with a substantially full width of the cabin space.
    Type: Grant
    Filed: August 5, 2004
    Date of Patent: May 23, 2006
    Assignee: Mazda Motor Corporation
    Inventors: Tamio Miyahara, Kazuhiro Matsuhashi, Masahiro Maruyama, Yasukazu Watanabe, Akira Itoh