Abstract: A polysulfone-based hollow fiber membrane that purifies blood preparations, including a hydrophilic polymer on a surface thereof which contacts the blood preparation, wherein an abundance ratio of the hydrophilic polymer is from 40 to 60% by mass, and porosity at the surface is 8 to 30%.

Abstract: There is provided a porous membrane capable of achieving both virus-removing performance and water permeability. The porous membrane according to the present invention has an average pore minor axis diameter of 10 nm or more and 90 nm or less in at least one surface of the porous membrane; a thickness of 60 ?m to 300 ?m; and an overall adsorption capacity with respect to bacteriophage MS2 of 8×109 PFU/g or more.

Abstract: A hollow fiber membrane module is capable of producing washed platelets having a low total protein amount and a high total platelet count from a platelet suspension. The hollow fiber membrane module for washing platelets by removal of impurities from a platelet suspension includes a housing having a platelet suspension inlet, washed platelet outlet, and filtrate outlet; and a hollow fiber membrane for filtering the platelet suspension, wherein pores through which the platelets do not pass, while the impurities pass, are formed, which hollow fiber membrane is arranged inside the housing; wherein the capacity of the inlet-side space which communicates with the platelet suspension inlet and stores the platelet suspension before being filtered through the hollow fiber membrane in the housing is 30 to 400 mL, and the module water permeability is 50 to 300 mL/Pa/hr.

Abstract: A method of producing a platelet solution replaced with an artificial preservation solution includes a filtering step of carrying out cross-flow filtration of a platelet solution under the conditions of Formula (1) at an inlet wall shear rate of 25 to 1500 s?1 using a separation membrane whose surface which contacts with the platelet solution has an average pore size of not less than 0.1 ?m and less than 2.0 ?m, thereby obtaining a concentrated platelet solution; and a mixing step of mixing the concentrated platelet solution with an artificial preservation solution to obtain the platelet solution replaced with an artificial preservation solution: 1.0×1011<(A×B)/(?×?P)?2.5×1013 (platelets/(hr·m2·Pa))??(1) A: Concentration of platelets contained in the platelet solution (platelets/mL; with the proviso that the range is 8.0×107 to 200×107 platelets/mL) B: Filtration flow rate per unit area (mL/hr/m2) ?: Inlet wall shear rate (s?1) ?P: Viscosity of the platelet solution (Pa·s).

Abstract: The present invention addresses the problem of providing a porous membrane for a water purification purpose, which can be used even under high water pressures and which has both virus-removing performance and water permeability. The problem can be solved as follows: a porous membrane is provided, wherein the average pore shorter-axis diameter in one surface is smaller than that in the other surface, and in a cross section of the membrane in the thickness direction, the pore diameters increase from one surface toward the other surface to have at least one maximum value and then decrease. The membrane has a layer which is provided on the side of the surface having a larger average pore shorter-axis diameter and which has pore diameters of 130 nm or less in the cross section of the membrane, wherein the layer has a thickness of 0.5 to 20 ?m inclusive and the layer has pores each having a pore diameter of 100 to 130 nm inclusive.

Abstract: An object of the present invention is to provide a dry-type hollow fiber membrane module which is excellent in blood compatibility and elutes little eluted substance, and a hollow fiber membrane built in the module, and a method for producing a hollow fiber membrane module. Disclosed is a hollow fiber membrane module including a built-in hollow fiber membrane including a hydrophobic polymer and a hydrophilic group-containing polymer, the hollow fiber membrane module satisfying the following items: (a) the water content of the hollow fiber membrane is 10% by weight or less relative to the tare weight of the hollow fiber membrane, (b) the hydrophobic polymer contains no nitrogen, the hydrophilic group-containing polymer contains nitrogen, and the nitrogen content of the hollow fiber membrane is 0.05% by weight or more and 0.

Abstract: A method of producing a platelet solution replaced with an artificial preservation solution includes a filtering step of carrying out cross-flow filtration of a platelet solution under the conditions of Formula (1) at an inlet wall shear rate of 25 to 1500 s?1 using a separation membrane whose surface which contacts with the platelet solution has an average pore size of not less than 0.1 ?m and less than 2.0 ?m, thereby obtaining a concentrated platelet solution; and a mixing step of mixing the concentrated platelet solution with an artificial preservation solution to obtain the platelet solution replaced with an artificial preservation solution: 1.0×1011<(A×B)/(?×?P)?2.5×1013 (platelets/(hr·m2·Pa))??(1) A: Concentration of platelets contained in the platelet solution (platelets/mL; with the proviso that the range is 8.0×107 to 200×107 platelets/mL) B: Filtration flow rate per unit area (mL/hr/m2) ?: Inlet wall shear rate (s?1) ?P: Viscosity of the platelet solution (Pa·s).

Abstract: A polysulfone-based hollow fiber membrane that purifies blood preparations, including a hydrophilic polymer on a surface thereof which contacts the blood preparation, wherein an abundance ratio of the hydrophilic polymer is from 40 to 60% by mass, and porosity at the surface is 8 to 30%.

Abstract: A membrane separation culture device includes an upper structure including a vessel in which at least a portion of the bottom thereof is formed with a separation membrane having pores that allow stem cells to permeate therethrough, and a lower structure including a vessel that retains a fluid in which the membrane of the upper structure is immersed.

Abstract: A water vapor permeable membrane is provided comprising a dense layer and a support layer that are adjacent to each other, wherein the dense layer contains voids with a void length of 0.1 ?m or less and the dense layer has a thickness of 0.1 ?m or more and 2 ?m or less while in the support layer, void (a), i.e. the void with the largest length in the 2 ?m thick region measured from the boundary between the dense layer and the support layer into the support layer, has a length of 0.3 ?m or more and void (b), i.e. the void with the largest length in the region ranging between 2 ?m and 4 ?m measured from the boundary into the support layer, has a length of 0.5 ?m or more, the length of the void (b) being larger than that of the void (a). A water vapor permeable membrane having both a high water vapor permeability and a low air leakage is provided.

Abstract: A water vapor permeable membrane is provided comprising a dense layer and a support layer that are adjacent to each other, wherein the dense layer contains voids with a void length of 0.1 ?m or less and the dense layer has a thickness of 0.1 ?m or more and 2 ?m or less while in the support layer, void (a), i.e. the void with the largest length in the 2 ?m thick region measured from the boundary between the dense layer and the support layer into the support layer, has a length of 0.3 ?m or more and void (b), i.e. the void with the largest length in the region ranging between 2 ?m and 4 ?m measured from the boundary into the support layer, has a length of 0.5 ?m or more, the length of the void (b) being larger than that of the void (a). A water vapor permeable membrane having both a high water vapor permeability and a low air leakage is provided.

Abstract: The present invention provides hollow fiber membranes and a hollow fiber membrane module having the same included therein, which even when highly filled, can reduce the size of the module and simultaneously maintain a crimped state enabling a good flow of a dialysate or buffer in the module by an easy process, characterized in that the hollow fiber membrane is provided with a crimp having a wavelength of 15 to 25 mm and a crimp angle determined by the wavelength and an amplitude of 0.09 to 0.32.