Patents by Inventor Masahito Nakazaki

Masahito Nakazaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240122988
    Abstract: The present invention relates to a synapse formation promoter and a brain plasticity promoter comprising CD24-negative mesenchymal stem cells prepared from a patient's own bone marrow aspirate and treatment of dementia, chronic-phase cerebral infarction, chronic-phase spinal cord injury, mental diseases, and the like using the synapse formation promoter and brain plasticity promoter.
    Type: Application
    Filed: April 26, 2023
    Publication date: April 18, 2024
    Applicants: Sapporo Medical University, Nipro Corporation
    Inventors: Osamu Honmou, Masanori Sasaki, Rie Maezawa, Shinichi Oka, Yuko Sasaki, Masahito Nakazaki, Toshihiko Yamashita
  • Patent number: 11666601
    Abstract: The present invention relates to a synapse formation promoter and a brain plasticity promoter comprising CD24-negative mesenchymal stem cells prepared from a patient's own bone marrow aspirate and treatment of dementia, chronic-phase cerebral infarction, chronic-phase spinal cord injury, mental diseases, and the like using the synapse formation promoter and brain plasticity promoter.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: June 6, 2023
    Assignees: Sapporo Medical University, Nipro Corporation
    Inventors: Osamu Honmou, Masanori Sasaki, Rie Maezawa, Shinichi Oka, Yuko Sasaki, Masahito Nakazaki, Toshihiko Yamashita
  • Publication number: 20220133805
    Abstract: The present invention relates to a pharmaceutical composition for treating amyotrophic lateral sclerosis. More specifically, the present invention relates to a pharmaceutical composition for treating amyotrophic lateral sclerosis, wherein the pharmaceutical composition comprises mesenchymal stem cells and is intravenously administered.
    Type: Application
    Filed: March 13, 2020
    Publication date: May 5, 2022
    Applicants: Sapporo Medical University, Nipro Corporation
    Inventors: Osamu HONMOU, Masanori SASAKI, Yuko SASAKI, Shinichi OKA, Masahito NAKAZAKI, Rie MAEZAWA
  • Publication number: 20220125850
    Abstract: The present invention relates to a pharmaceutical composition containing mesenchymal stem cells administered to a patient subjected to stenting. The present invention relates specifically to: a pharmaceutical composition for repairing and regenerating tissue, comprising mesenchymal stem cells, wherein the pharmaceutical composition is administered to a patient subjected to stenting; and the prevention of in-stent neointimal hyperplasia or in-stent restenosis with the pharmaceutical composition.
    Type: Application
    Filed: February 7, 2020
    Publication date: April 28, 2022
    Applicants: Sapporo Medical University, Nipro Corporation
    Inventors: Osamu HONMOU, Masanori SASAKI, Yuko SASAKI, Shinichi OKA, Masahito NAKAZAKI, Rie MAEZAWA
  • Publication number: 20190183937
    Abstract: The present invention relates to a life extension agent containing CD24-negative mesenchymal stem cells and the treatment of dementia, cerebral infarction, spinal cord injury and the like using the life extension agent.
    Type: Application
    Filed: April 13, 2017
    Publication date: June 20, 2019
    Applicants: Sapporo Medical University, Nipro Corporation
    Inventors: Osamu Honmou, Masanori Sasaki, Yuko Sasaki, Rie Maezawa, Shinichi Oka, Masahito Nakazaki
  • Publication number: 20190117700
    Abstract: The present invention relates to a synapse formation promoter and a brain plasticity promoter comprising CD24-negative mesenchymal stem cells prepared from a patient's own bone marrow aspirate and treatment of dementia, chronic-phase cerebral infarction, chronic-phase spinal cord injury, mental diseases, and the like using the synapse formation promoter and brain plasticity promoter.
    Type: Application
    Filed: April 26, 2017
    Publication date: April 25, 2019
    Applicants: Sapporo Medical University, Nipro Corporation
    Inventors: Osamu Honmou, Masanori SASAKI, Rie MAEZAWA, Shinichi OKA, Yuko SASAKI, Masahito NAKAZAKI, Toshihiko YAMASHITA
  • Publication number: 20190002833
    Abstract: Provided is new means for reducing risk of cerebral hemorrhage associated with a reperfusion therapy for vessel occlusion (for example, administration of a medicament including a thrombolytic agent, a platelet aggregation inhibitor, and an anticoagulant agent, or physical removal of a blood clot) and treating an ischemic vascular disorder more effectively. The present invention relates to a medicament for treating an ischemic vascular disorder, comprising mesenchymal stem cells, wherein the medicament is used in combination with a reperfusion therapy for vessel occlusion and more specifically, to a medicament for treating an ischemic vascular disorder, wherein the medicament reduces risk of cerebral hemorrhage associated with the reperfusion therapy for vessel occlusion and extends a time window in which the therapy is applicable.
    Type: Application
    Filed: December 26, 2016
    Publication date: January 3, 2019
    Applicants: Sapporo Medical University, Nipro Corporation
    Inventors: Osamu Honmou, Masahito Nakazaki, Masanori Sasaki, Yuko Sasaki, Shinichi Oka