Patents by Inventor Masahito Ochiai

Masahito Ochiai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1H-Cyclopenta[b]benzofuran derivative and its analog
    Patent number: 4539414
    Abstract: Substantially pure compounds having the general formula ##STR1## wherein (1) ##STR2## R.sup.2 is .beta.-hydroxy and R.sup.3 and R.sup.4 together form an oxygen bridge, or (2) ##STR3## R.sup.2 and R.sup.3 together form an additional carbon-carbon bond, and R.sup.4 is hydroxy, are disclosed. These compounds exhibit antileukemic activity against P388 lymphocytic leukemia in CDF.sub.1 mice and inhibitory activity in vitro against cells derived from human epidermoid carcinoma of the nasopharynx(KB) cells.
    Type: Grant
    Filed: October 14, 1983
    Date of Patent: September 3, 1985
    Inventors: Ming L. King, Chin-Chih Chiang, Han-Chin Ling, Masahito Ochiai, Eiichi Fujita, Andrew T. McPhail