Abstract: An L-amino acid can be produced by culturing an L-amino acid-producing bacterium which belongs to the Enterobacteriaceae family and which has been modified so that the expression of a yggG gene is enhanced.

Abstract: Three-dimensional information on a biological parameter relating to at least one selected from viability, proliferating ability, migration, and differentiation of cultured cells can be obtained by a simple two-dimensional analytical technique by constructing a cell evaluation system including a multilayered cell sheet, target cells, and a two-dimensional analyzer.

Abstract: An L-amino acid can be produced by culturing an L-amino acid-producing bacterium which belongs to the Enterobacteriaceae family and which has been modified so that the expression of a yggG gene is enhanced.

Abstract: A control device of a detached cells collection apparatus first closes an exhaust pipe and opens an injection pipe to inject a predetermined quantity of a trypsin solution into a culture chamber, starts counting trypsin processing time, and inclines a support table when the counted trypsin processing time reaches a preset time period. The control device simultaneously opens the exhaust pipe and makes the trypsin solution including detached cells in the culture chamber flown through the exhaust pipe to a collection chamber. On completion of such collection, the support table is returned to its horizontal orientation and a new collection chamber is set in the detached cells collection apparatus. The control device again closes the exhaust pipe and opens the injection pipe to inject the predetermined quantity of the trypsin solution into the culture chamber and resumes counting the trypsin processing time. This series of operations is repeated to collect cells according to the trypsin processing time.

Abstract: A method for evaluating the proliferation ability of an entire cell population by observing each anchorage-dependent cell without invading and destroying the cell. The evaluation method includes monolayer-culturing anchorage-dependent cells in a culturing chamber, imaging each cell, calculating an index related to the proliferation ability of each cell using the image of each cell, and evaluating the proliferation ability of the cell population using the index. The index includes an expansion speed (rs) indicative of a change in a projected area of each cell (Sa) during a cell adhesion phase, the number of cells contacting each cell in a cell proliferation phase, and a projected area (Sa′) of each cell in the cell-proliferation phase.

Abstract: A cell culture device which facilitates a culture operation while maintaining conditions suited for culture of cells. A cell culture device 11 comprises first and second culture units 12a and 12b, a cell feed unit 14, a liquid feed unit 15, a liquid waste tank 16, a gas exchange unit 18, and a control unit 101. Cells are cultured in the first and second culture units 12a and 12b. A CCD camera 22 provides image data of the cells to the control unit 101. The control unit calculates concentration of the cells from the image data and determines timings to replace a culture medium and perform subculture in accordance with the concentration.

Abstract: A biocidal material comprising, as an active ingredient, a compound represented by General Formula (1)