Patents by Inventor Masaji Matsunaga
Masaji Matsunaga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20090272392Abstract: [PROBLEMS] To provide a cigarette filter that does not impair the distinctive flavor of a cigarette and the air permeability of filter while smoking, and at the same time, can more effectively remove harmful substances such as a pyrene that is generated from the cigarette. [MEANS FOR SOLVING PROBLEMS] The cigarette filter comprising a filter fiber bundle body which cigarette smoke passes through; a fine powder with a high surface area ratio that are mixed and scattered in the filter fiber bundle body; and a double-stranded DNA molecule attached to the outer surface of the fine powder with a high surface area ratio, characterized in that harmful substances such as benzo[a]pyrene contained in the cigarette smoke can be removed by intercalation into the double-stranded DNA molecule.Type: ApplicationFiled: April 28, 2005Publication date: November 5, 2009Applicants: NISSEI BIO CO., LTD., NATIONAL UNIVERSITY CORPORATION hOKKAIDO UNIVERSITYInventors: Xiang Dong Liu, Masaji Matsunaga, Norio Nishi
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Publication number: 20090183745Abstract: [Problem to be Solved] To provide a cigarette filter capable of very effectively adsorbing/eliminating carcinogens such as dioxins and benzpyrene in mainstream smoke generated in cigarette smoking, and maintaining the flavor characteristic of cigarette and air permeability of cigarette filter. [Solution] Provided is a cigarette filter containing a harmful substance-eliminating material comprising a double-stranded DNA and/or a corn cob powder.Type: ApplicationFiled: October 12, 2005Publication date: July 23, 2009Applicant: NISSEI BIO COMPANY, LIMITEDInventors: Masaji Matsunaga, Fumito Yoshida
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Publication number: 20090036385Abstract: It is intended to provide a hair care preparation. The invention is directed to a hair care preparation (a hair regrowth agent, a hair restorer or an agent for preventing hair loss) comprising as an effective component, an enzymatic or hydrolytic degradation product of a nucleoprotein and/or DNA or RNA, a deoxyoligonucleotide, a deoxymononucleotide, an oligopeptide, an oligonucleotide or a mononucleotide separated from the degradation product, or a mixture of at least two members selected from the degradation products or compounds. The effective component such as a deoxyloligonucleotide has a relatively small molecular weight, therefore, it is easy to be percutaneously absorbed. Further it has a cell activation effect and a blood circulation-promoting effect when it is percutaneously absorbed. Therefore, when it is applied to the scalp, an excellent hair regrowth-promoting effect, hair restoration effect and effect of preventing hair loss are exhibited.Type: ApplicationFiled: January 18, 2006Publication date: February 5, 2009Applicant: NISSEI BIO CO., LTD.Inventor: Masaji Matsunaga
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Publication number: 20080314007Abstract: There is provided a filter simultaneously having the effects of not only being capable of effectively remove toxic substances such as benzo[a]pyrene, contained in outdoor air and indoor air but also being substantially free from any deterioration of dust collection effectiveness.Type: ApplicationFiled: January 18, 2006Publication date: December 25, 2008Applicant: Nissei BIO CO., Ltd.Inventor: Masaji Matsunaga
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Publication number: 20080173177Abstract: A method and a filter for efficiently removing harmful substances in ambient air or generated from tobacco, such as dioxins and pyrene, using DNA are provided. Specifically, in the method, gas containing harmful substances is brought into contact with DNA to be trapped by the DNA, thereby being removed. The filter for removing harmful substances includes DNA and a supporter for supporting the DNA.Type: ApplicationFiled: March 26, 2008Publication date: July 24, 2008Applicant: Nissei Bio Co., Ltd.Inventors: Xiang Dong Liu, Masaji Matsunaga, Norio Nishi
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Publication number: 20080161229Abstract: The present invention relates to a compounding ingredients for basic cosmetics and basic cosmetics containing the compounding ingredients which contain enzymes or hydrolysis products of nucleoprotein and/or DNA or RNA, or deoxy oligonucleotide, deoxy mononucleotide, oligopeptide, oligonucleotide mononucleotide separated from the hydrolysis products, or at least two kinds of mixtures selected from the hydrolysis products or compounds as active ingredients. Because the active ingredients such as deoxy oligonucleotide and others have comparatively small molecular weights, they are easy to be absorbed percutaneously, and when they are percutaneously absorbed, they exhibit cellular stimulating effects and blood circulation promoting effects, and therefore, in the event that they are applied to the facial skin, they marvelously prevent skin roughness, blotches, freckles, wrinkles, etc. and exhibit superb skin-lightening effects.Type: ApplicationFiled: September 25, 2007Publication date: July 3, 2008Applicant: NISSEI BIO CO., LTD.Inventors: Masaji Matsunaga, Fumito Yoshida, Takao Mori
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Publication number: 20080153741Abstract: It is intended to provide compounding ingredients for cosmetics for improving skinditch density and cosmetics. The present invention provides compounding ingredients for cosmetics containing, as an active ingredient, nucleoprotein and/or DNA or RNA enzymatic or hydrolytic degradation product(s), a deoxyoligonucleotide, deoxymononucleotide, oligopeptide, oligonucleotide, or mononucleotide separated from the degradation product, or a mixture of at least two members selected from the degradation products and the compounds, and cosmetics containing the compounding ingredients for cosmetics. The active ingredients such as the deoxyoligonucleotide have a relatively small molecular weight and as such, are easily transdermally absorbed. The transdermally absorbed active ingredients promote skin cellular regeneration or activation.Type: ApplicationFiled: September 25, 2007Publication date: June 26, 2008Applicant: NISSEI BIO CO., LTD.Inventors: Masaji Matsunaga, Fumito Yoshida, Takao Mori, Masahito Sugi, Eishi Hasegawa
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Publication number: 20080145440Abstract: According to the present invention, an early-phase release amount of cisplatin (CCDP) is reduced and a release of cisplatin is maintained over a long period of time, such that an anticancer effect against cancer cells is enhanced while side effects are reduced. In this manner, a life prolongation effect for patients is enhanced. A microparticle preparation contains cisplatin that is intercalated into double-helical DNA. The microparticle preparation stably retains cisplatin and exhibits an excellent slow-release property. Accordingly, even when cisplatin containing severe toxicity is used, the side effects can be suppressed and an excellent anticancer effect can be provided over a long period of time.Type: ApplicationFiled: June 19, 2007Publication date: June 19, 2008Applicants: NISSEI BIO COMPANY, LIMITED, Suong Hyu HyonInventors: Han Hee Cho, Long Hai Han, Kazuaki Matsumura, Sadami Tsutsumi, Suong Hyu Hyon, Masaji Matsunaga, Fumihito Yoshida
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Publication number: 20060110816Abstract: There is provided a method of removing harmful substance characterized by comprising contacting a harmful substance-containing liquid to be treated with a double-stranded DNA, adsorbing the harmful substance onto the double-stranded DNA through intercalation, and separating it. The method is particularly useful for removing dioxins, and can be carried out by contacting a liquid to be treated with an adsorbent comprising a double-stranded DNA or a solution containing a double-stranded DNA enclosed in a container or a bag made of a membrane that is permeable for the harmful substance but is not permeable for the double-stranded DNA.Type: ApplicationFiled: November 17, 2003Publication date: May 25, 2006Applicant: NISSEI BIO CO., LTD.Inventors: Xiang Liu, Masaji Matsunaga, Norio Nishi
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Publication number: 20040211728Abstract: A method and a filter for efficiently removing harmful substances in ambient air or generated from tobacco, such as dioxins and pyrene, using DNA are provided.Type: ApplicationFiled: December 2, 2003Publication date: October 28, 2004Inventors: Xiang Dong Liu, Masaji Matsunaga, Norio Nishi
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Patent number: 5681403Abstract: A magnesium Mg--Al--RE magnesium alloy wherein an amount of a rare earth component may be reduced while optimial tensile strength and durability are obtained. The Alloy further includes a small calcium component. A high degree of creep resistance is obtained. Further, additional copper and/or zinc components may be introduced together, or singly for providing favorable tensile characteristics to the alloy material.Type: GrantFiled: December 27, 1994Date of Patent: October 28, 1997Assignees: Nissan Motor Co., Ltd., Ube Industries, Ltd.Inventors: Kunihiko Makino, Toshiro Kawata, Kyosuke Kanemitsu, Koji Watanabe, Masaji Matsunaga, Mamoru Sayashi
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Patent number: 5014604Abstract: An internally-chilled piston for an internal combustion engine is provided. This piston comprises a piston body made of an aluminum alloy and a piston head including a cylindrical member and a ring-shaped member engaging the outer peripheral surface of the cylindrical member by a shrink fit bonding. The cylindrical member constitutes the central portion of the piston head, while the ring-shaped member constitutes the periphery thereof. On the surface of the ring-shaped member which contacts with the melt forming the piston body during casting, an aluminized layer is formed which chemically connects the ring-shaped member and the piston body to increase the mechanical strength of bonding therebetween.Type: GrantFiled: October 13, 1989Date of Patent: May 14, 1991Assignees: Nissan Motor Company, Limited, Atsugi Unisia CorporationInventors: Sumio Hirao, Masaji Matsunaga, Yoshihiro Yamada
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Patent number: 4643757Abstract: Pyrazole derivatives, selective herbicidal compositions containing said derivatives and the use of said derivatives are provided. The pyrazole derivatives having selective herbicidal activity are represented by the formula I: ##STR1## wherein, X denotes a halogen, nitro or methanesulfonyl,Y denotes hydrogen, a lower alkyl or a halogen,Z denotes a halogen or methanesulfonyl, andR denotes hydrogen; an organic acid residue; a lower alkynyl; a lower alkyl or a lower alkenyl which may be substituted by a halogen, hydroxy, cyano or an alkoxycarbonyl; or a benzyl which may be substituted by a halogen, nitro or a lower alkyl.Type: GrantFiled: May 20, 1985Date of Patent: February 17, 1987Assignee: Nissan Chemical Industries, Ltd.Inventors: Masatoshi Baba, Norio Tanaka, Takasi Ikai, Tsutomu Nawamaki, Masaji Matsunaga
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Patent number: 4557753Abstract: Pyrazole derivatives, preparations thereof, selective herbicidal compositions containing said derivatives and the use of said derivatives are provided. The pyrazole derivatives having selective herbicidal activity are represented by the formula I: ##STR1## wherein, A denotes a straight or branched lower alkylene or lower alkylidene group; X denotes a halogen atom, nitro group, a lower alkyl group, a lower haloalkyl group, a lower alkoxy group, a lower haloalkoxy group, a lower alkenyl group, phenyl group, cyano group, phenoxy group, a lower alkoxycarbonyl group, an aliphatic or aromatic acyl group, methanesulfonyloxy group or group ##STR2## and n is 0 or an integer of 1 to 5, said Xs being the same or different when n is an integer of 2 to 5; and Y denotes a halogen atom, a lower alkyl group, nitro group, phenyl group, a lower alkoxy group or trifluoromethyl group and m is in integer of 1 to 3, said Ys being the same or different when m is 2 or 3.Type: GrantFiled: April 18, 1983Date of Patent: December 10, 1985Assignee: Nissan Chemical Industries Ltd.Inventors: Norio Tanaka, Masakazu Taniguchi, Masatoshi Baba, Takashi Ikai, Tsutomu Nawamaki, Masaji Matsunaga