Patents by Inventor Masakatsu Furui

Masakatsu Furui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing optically active trans-3-substituted glycidic acid ester
    Patent number: 6197953
    Abstract: Methods for the preparation of (2S,3S)-1,5-benzothiazepine derivatives of the formula (II) and isomers thereof, and for the preparation of (2R,3R)-1,5-benzothiazepine derivatives of the formula (III) and isomers thereof, wherein ring A and ring B are independently a substituted or unsubstituted benzene ring, and R2 is a 2-(dimethylamino)ethyl group or a group of the formula: or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 16, 1999
    Date of Patent: March 6, 2001
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masakatsu Furui, Toshiyuki Furutani
  • Process for preparing optically active trans-3-substituted glycidic acid ester
    Patent number: 5998637
    Abstract: A process for preparing an optically active trans-3-substituted glycidic acid ester compound of the formula (I): ##STR1## wherein ring A is a substituted or unsubstituted benzene ring, and R.sup.1 is an ester residue, which comprises:preparing a solution of one optical isomer (A) and the other optical isomer (B) of the ester compound (I), both of which are the optical isomers due to the asymmetric carbons at 2- and 3-positions, and an ester compound (B') which is different from the isomer (B) only in the ester residue R.sup.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: December 7, 1999
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masakatsu Furui, Toshiyuki Furutani
  • Process for preparing D-amino acids
    Patent number: 5783427
    Abstract: Disclosed is a process for preparing a D-amino acid selected from the group consisting of D-methionine, D-valine, D-leucine, D-isoleucine and D-histidine, which comprises the steps of:making a culture or treated culture of a microorganism having ability to asymmetrically degrade a L-amino acid selected from the group consisting of L-methionine, L-valine, L-leucine, L-isoleucine and L-histidine act on a corresponding racemic amino acid to the L-amino acid; andseparating and collecting the remaining D-amino acid.
    Type: Grant
    Filed: March 26, 1996
    Date of Patent: July 21, 1998
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masakatsu Furui, Eiji Takahashi, Hiroyasu Seko, Takeji Shibatani
  • Process for preparing D-lysine
    Patent number: 5723321
    Abstract: A process for preparing D-lysine using a microorganism which has the ability to asymmetrically degrade L-lysine in a reaction medium is disclosed. The process is performed by first bringing racemic lysine into contact with a culture or a treated culture of the microorganism, and then collecting and isolating the D-lysine from the reaction mixture.
    Type: Grant
    Filed: December 21, 1995
    Date of Patent: March 3, 1998
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masakatsu Furui, Eiji Takahashi, Hiroyasu Seko
  • Process for producing D-mandelic acid from benzoylformic acid
    Patent number: 5441888
    Abstract: There is disclosed a process for preparing D-mandelic acid comprising the steps of:(1) treating racemic mandelic acid with a culture broth, cells or treated cells of a microorganism having ability of converting L-mandelic acid into benzoylformic acid.(2) treating the reaction mixture of the step (1) with a culture broth, cells or treated cells of a microorganism having ability of stereoselectively reducing benzoylformic acid into D-mandelic acid, and(3) isolating and collecting the D-mandelic acid from the reaction mixture.
    Type: Grant
    Filed: October 29, 1993
    Date of Patent: August 15, 1995
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Takao Mori, Masakatsu Furui, Katsuhiko Nakamichi, Eiji Takahashi