Patents by Inventor Masaki Aburada

Masaki Aburada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neurotensin Hexapeptides
    Patent number: 5393740
    Abstract: A hexapeptide represented by formula (II):A-B-Pro-C-D-E (I)where A represents an L- or D- form of arginine or lysine whose N-terminal amino group is alkylated or acylated, B represents an L- or D- form of argine, lysine, or histidine, Pro represents an L- or D- form of proline, C represents an L- or D- form of tyrosine, tryptophan, or phenylalanine, D represents an L- or D- form of valine, isolencine, or leucine, and E represents an L-or D- form of valine, isolencine, or lencine, one of the hydrogen atoms of the amino group of which may be substituted a C.sub.1 to C.sub.4 alkyl group, and C-terminal carboxyl group of which is substituted with --COOR*, --CH.sub.2 OR, or --CONHR wherein R* represents a C.sub.1 to C.sub.4 alkyl group, and R represents a hydrogen atom or an C.sub.1 to C.sub.4 alkyl group.
    Type: Grant
    Filed: July 28, 1992
    Date of Patent: February 28, 1995
    Assignee: Tsumura & Co.
    Inventors: Sakae Amagaya, Tadami Fujiwara, Masaki Aburada, Michio Nagasawa, Tsutomu Oyama
  • Preparation for reducing cancer symptoms without treating cancer
    Patent number: 4618495
    Abstract: A composition for reducing cancer symptoms by improving lipid metabolism and eliminating or reducing anorexia in tumor-bearing patients through inhibition of the lipid degradation-promoting action of toxohormone L which comprises an aqueous or aqueous organic solvent extract of one or more crude preparations selected from the group consisting of Astragali radix, Cinnamomi cortex, Rehmanniae radix, Paeoniae radix, Cnidii rhizoma, Atractylodis lanceae rhizoma, Angelicae radix, Ginseng radix, Hoelen and Glycyrrhizae radix, a method for preparing such a composition, and a method for reducing cancer symptoms using the composition.
    Type: Grant
    Filed: February 14, 1985
    Date of Patent: October 21, 1986
    Assignee: Tsumura Juntendo Inc.
    Inventors: Hiromichi Okuda, Hiroshi Masuno, Masaki Aburada, Shigefumi Takeda, Eiko Itoh, Moe Matsushita, Eikichi Hosoya
  • Adminiculum for antitumor agents
    Patent number: 4613591
    Abstract: Adminiculum increasing the antitumor activities of mitomycin C and doxorubicin hydrochloride and decreasing the side effects associated with their use comprising an aqueous or aqueous organic solvent extract of a crude preparation of Astragali radix, Cinnamomi cortex, Rehmanniae radix, Paeoniae radix, Cnidii rhizoma, Atractylodis lanceae rhizoma, Angelicae radix, Ginseng radix, Hoelen and Glycyrrhizae radix, a method for preparing said adminiculum and a method for its use. In addition, compositions and methods for treating tumor-bearing patients are disclosed.
    Type: Grant
    Filed: June 29, 1983
    Date of Patent: September 23, 1986
    Assignee: Tsumura Juntendo Inc.
    Inventors: Masaki Aburada, Shigefumi Takeda, Eiko Itoh, Moe Matsushita, Eikichi Hosoya