Patents by Inventor Masaki Kanai
Masaki Kanai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210138482Abstract: A field-flow fractionation device includes a separation channel, a carrier fluid supplier, a separation membrane, a waste liquid chamber, a cross-flow flow rate adjuster, and a carrier fluid adder. The carrier fluid adder is configured to add, to a flow of a carrier fluid having passed through the separation membrane, a flow of another carrier fluid at a carrier fluid adding position set on an upstream side of the cross-flow flow rate adjuster so that the flow rate of the carrier fluid flowing into the cross-flow flow rate adjuster is larger than the flow rate of the carrier fluid having passed through the separation membrane.Type: ApplicationFiled: April 11, 2018Publication date: May 13, 2021Applicant: SHIMADZU CORPORATIONInventors: Shigeyoshi HORIIKE, Jun YANAGIBAYASHI, Yukio OIKAWA, Maiko NAKAYA, Masaki KANAI
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Publication number: 20210129158Abstract: In a magnetic particle operation device 1, a plurality of liquid layers 11 and a plurality of gel-like medium layers are alternately arranged. Magnetic particles 13 are introduced into the uppermost liquid layer 11 of the magnetic particle operation device 1, and a holding magnet 60 is in contact with the outer surface of the bulging portion 21 of the container 20. Therefore, during the storage of the device 1, the magnetic particles 13 in the bulging portion 21 are aggregated and held at a position facing the holding magnet 60 in the sample introduction space by the magnetic force of the holding magnet 60. As a result, during the storage of the device 1, the magnetic particles 13 can be prevented from being brought into contact with the gel-like medium layer 12. Further, when the device 1 is used, the magnetic particles 13 can be dispersed in the liquid layer 11 by moving the holding magnet 60 away from the container 20.Type: ApplicationFiled: April 6, 2017Publication date: May 6, 2021Inventors: Masaki KANAI, Hiroyuki JIKUYA, Tetsuo OHASHI, Seiya FUJIWARA
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Patent number: 10941394Abstract: A device for manipulating magnetic particles includes a gelled medium layer and liquid layers alternately stacked in a tubular container along a longitudinal direction of the container. A magnetic particle movement portion for moving magnetic particles exists along an inner wall surface of the container, and the magnetic particle movement portion extends along the longitudinal direction of the container. At a portion where the gelled medium layer is loaded, the cross-sectional shape of the container inner wall in a plane perpendicular to the longitudinal direction of the container is non-circular, and the shape of the magnetic particle movement portion in the cross section is a curved shape or an angular shape.Type: GrantFiled: January 15, 2015Date of Patent: March 9, 2021Assignee: SHIMADZU CORPORATIONInventors: Masaki Kanai, Tetsuo Ohashi, Takahiro Nishimoto
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Patent number: 10885786Abstract: A protected region is set for a manned working machine, said region including a first protected region in which new protected region setting request information is not transmitted and which includes the position of the manned working machine, and a second protected region which is set along a periphery of the first protected region and in which new protected region setting request information is transmitted. An area occupied by the vehicle body of the manned working machine on a plane projected on the ground surface is calculated on the basis of vehicle body information indicating the size of the vehicle body of the manned working machine and position information thereof. When the occupied area is present within the first protected region, new protected region setting request information is not transmitted, whereas when the occupied area is present within the second protected region, protected region setting request information is transmitted.Type: GrantFiled: September 15, 2017Date of Patent: January 5, 2021Assignee: HITACHI CONSTRUCTION MACHINERY CO., LTD.Inventors: Wataru Tanaka, Masaki Kanai, Tomoyuki Hamada
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Publication number: 20200282407Abstract: An operation pipe and a device equipped with the operation pipe, which use a gel to perform operations such as separation, extraction, purification, elution, recovery, analysis and the like of target components that are biological components such as nucleic acids. More specifically, an operation pipe and a device, with which it is possible to perform operations such as separation, extraction, purification, elution, recovery, analysis and the like of target components in a sealable pipe by operating magnetic particles in the pipe under a magnetic field from outside of the pipe.Type: ApplicationFiled: February 5, 2020Publication date: September 10, 2020Applicant: SHIMADZU CORPORATIONInventors: Masamitsu SHIKATA, Ayaka MINAMIMOTO, Akira MURAMATSU, Masaki KANAI, Seiya FUJIWARA, Tetsuo OHASHI, Hiroyuki JIKUYA
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Publication number: 20200224138Abstract: To provide a cell treatment container, including: a first member having a flow path in which a cell suspension including a liquid and cells dispersed in the liquid flows through, the flow path formed on a surface of the first member; a second member arranged to face the surface of the first member; and a damming formed in one or both of the first member and the second member, in which the damming is provided with a protrusion part protruding from the first member into the flow path to form a gap for allowing the liquid in the cell suspension to pass through the gap and for damming up the cells in the cell suspension, and a pillar extending from the protrusion part at a first end and being joined to the second member at a second end.Type: ApplicationFiled: December 12, 2019Publication date: July 16, 2020Inventors: Chikara MIYAKE, Masaki KANAI, Yoichi FUJIYAMA, Satoshi KURAMOTO
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Patent number: 10684279Abstract: To provide a device for operating magnetic particles capable of treating large quantity, and retaining a gel-like medium layer stably, a vessel is formed so that an area perpendicular to a longitudinal direction in a large-diameter part packed with a liquid layer is larger than an area perpendicular to the longitudinal direction in the small-diameter part packed with a gel-like medium layer. Therefore, in the vessel, it is possible to reduce the diameter of the small-diameter part while keeping the capacity of the large-diameter part large. As a result, in the vessel, it is possible to treat large quantity in the liquid layer, and it is possible to retain the gel-like medium layer stably.Type: GrantFiled: February 8, 2018Date of Patent: June 16, 2020Assignee: SHIMADZU CORPORATIONInventors: Masaki Kanai, Hiroyuki Jikuya, Tetsuo Ohashi, Seiya Fujiwara
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Publication number: 20190317057Abstract: A field flow fractionation apparatus includes a separation channel provided with an inlet port and an outlet port at both ends and forming a space through which a carrier fluid flows between the inlet port and the outlet port, a separation membrane which is a wall surface that defines the separation channel and is parallel to a channel flow in which a carrier fluid flows in the separation channel from the inlet port toward the outlet port, and has a property of permeating the carrier fluid and not permeating particles to be separated, and a discharge port that discharges the carrier fluid having permeated through the separation membrane to outside. At least a part of the surface of the separation membrane is an ion exchangeable region in which a functional group having ion exchangeability is modified.Type: ApplicationFiled: April 10, 2019Publication date: October 17, 2019Applicant: SHIMADZU CORPORATIONInventors: Yukio OIKAWA, Shigeyoshi Horiike, Maiko Nakaya, Masaki Kanai
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Patent number: 10446036Abstract: A traffic control system for a manned vehicle, traveling on one of plural lanes arranged side by side in a mine, and a traffic control device connected with the vehicle. A zone of the lane, on which the vehicle is traveling, is set as a first travel-permitted zone with a travel permission given to the vehicle only. Upon receipt of a request from the vehicle for a travel-permitted zone of another-lane with a travel permission given only to the vehicle on a lane adjacent the lane on which the vehicle is traveling, the traffic control device sets, as the travel-permitted zone of the another-lane, a zone including at least a part of a zone arranged on the adjacent lane side by side with the first travel-permitted zone, and transmits the travel-permitted zone of the another-lane to the vehicle, which the vehicle displays on a display screen.Type: GrantFiled: March 9, 2016Date of Patent: October 15, 2019Assignee: Hitachi Construction Machinery Co., Ltd.Inventors: Masaki Kanai, Manabu Katou, Tomoyuki Hamada
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Patent number: 10391483Abstract: A dispensing device for reducing the dead volume of a liquid sample includes a main channel connected to a sample inlet and a sample outlet, and branch channels connected to the main channel. Each branch channel is connected to a different liquid reservoir. High inflow-withstanding pressure sections are provided in the main channel between the branch channels and between the branch channel and the sample outlet. Each high inflow-withstanding pressure section has a channel inner wall forming a contact angle of 90° or larger with a liquid sample. A liquid sample enters the main channel through the sample inlet, reaches a branch point between the first branch channel and the main channel, flows into the first branch channel and the liquid reservoir, and then passes through the high inflow-withstanding pressure section to a branch point between the next branch channel and the main channel.Type: GrantFiled: November 22, 2013Date of Patent: August 27, 2019Assignee: SHIMADZU CORPORATIONInventors: Masaki Kanai, Takahiro Nishimoto, Masakazu Akechi, Nobuhiro Hanafusa
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Publication number: 20190244524Abstract: A protected region is set for a manned working machine, said region including a first protected region in which new protected region setting request information is not transmitted and which includes the position of the manned working machine, and a second protected region which is set along a periphery of the first protected region and in which new protected region setting request information is transmitted. An area occupied by the vehicle body of the manned working machine on a plane projected on the ground surface is calculated on the basis of vehicle body information indicating the size of the vehicle body of the manned working machine and position information thereof. When the occupied area is present within the first protected region, new protected region setting request information is not transmitted, whereas when the occupied area is present within the second protected region, protected region setting request information is transmitted.Type: ApplicationFiled: September 15, 2017Publication date: August 8, 2019Inventors: Wataru TANAKA, Masaki KANAI, Tomoyuki HAMADA
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Publication number: 20190136171Abstract: A well has a pair of side surfaces, and one of the side surfaces is in contact with a compartment of a first channel with a gas-permeable membrane being interposed therebetween and the other side surface is in contact with a compartment of a second channel with a gas-permeable membrane being interposed therebetween. The well is filled with a liquid cell culture medium, and in such a state, a high-concentration gas and a low-concentration gas, which are different in the concentration of a specific component from each other, are allowed to flow through the first and second channels, respectively, to form a concentration distribution of the specific component in the well.Type: ApplicationFiled: December 28, 2018Publication date: May 9, 2019Applicants: SHIMADZU CORPORATION, KYOTO UNIVERSITY, WASEDA UNIVERSITYInventors: Tatsuya Munaka, Hirohisa Abe, Masaki Kanai, Masakazu Akechi, Taira Maekawa, Shinya Kimura, Eishi Ashihara, Shuichi Shoji, Kentaro Kawai
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Patent number: 10255811Abstract: On a basis of a relative position of an obstacle 401, a size of the obstacle in an own vehicle 12 width direction and a width of the own vehicle 12, a maximum amount Dt of movement of the own vehicle 12 in the vehicle width direction as required to avoid the obstacle 401 is calculated. A point displaced over the maximum amount of movement toward a side of the adjacent lane from the relative position of the obstacle 401 is determined as an avoiding point 250. If a distance d between the avoiding point 250 and the adjacent lane is greater than the width Wm of the own vehicle 12, an avoiding path is generated for allowing the own vehicle 12 to pass the avoiding point 250.Type: GrantFiled: March 6, 2015Date of Patent: April 9, 2019Assignee: Hitachi Construction Machinery Co., Ltd.Inventors: Takuya Naka, Masaki Kanai, Takayuki Satou
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Patent number: 10241092Abstract: A gas chromatograph includes a column module for independently adjusting the temperature of a separation column. The column module is held by an oven with the separation column being horizontal. The column module includes the separation column for separating a sample gas into components, a column accommodating member accommodating inside the separation column while surrounding the separation column by a heat insulating member, and including a gap between the separation column and the heat insulating member for air to flow along the separation column, and a heater, provided inside the column accommodating member, for heating the separation column by being in direct or indirect contact with the separation column. The column accommodating member includes an air inlet port for introducing external air into the gap between the separation column and the heat insulating member, and an air outlet port for exhausting air in the gap.Type: GrantFiled: October 25, 2012Date of Patent: March 26, 2019Assignee: SHIMADZU CORPORATIONInventors: Masaki Kanai, Satoshi Matsuoka, Masanori Nishino, Takahiro Nishimoto
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Publication number: 20190078044Abstract: A cell culture container includes a storage container, a cell culture area, a culture solution supply unit, and a discharge unit. The cell culture area is a region for culturing cells, and is provided in the storage container. The culture solution supply unit supplies the culture solution into the cell culture area at a flow rate equal to or less than a predetermined flow rate. The discharge unit discharges the liquid in the cell culture area to the outside of the storage container. A rectification unit is a structure in which a plurality of outflow ports are uniformly arranged in a direction perpendicular to the flow direction of the culture solution from the culture solution supply unit to the discharge unit.Type: ApplicationFiled: March 16, 2016Publication date: March 14, 2019Applicants: Shimadzu Corporation, Yokohama City University, Osaka University, Kuraray Co., Ltd.Inventors: Tomoki OHKUBO, Masaki KANAI, Hirohisa ABE, Hideki TANIGUCHI, Masahiro KINOOKA, Goro KOBAYASHI, Takanori TAKEBE
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Publication number: 20190024142Abstract: A pretreatment kit includes a container (10) for particle manipulation, nucleic acid capture particles (70) capable of selectively binding to nucleic acid, aqueous-phase separation medium (21, 22, 23), a plurality of kinds of aqueous liquids (35, 31, 32, 38), and a nucleic acid for individual identification. The nucleic acid for individual identification is contained in at least one of the plurality of kinds of aqueous liquids or is bound onto the surfaces of the nucleic acid capture particles. The base sequence of the nucleic acid for individual identification contains an identification sequence including a base sequence noncomplementary to the nucleic acids contained in the biological sample. The pretreatment kit is used for separating nucleic acids from biological samples that contains nucleic acids and contaminants.Type: ApplicationFiled: January 18, 2017Publication date: January 24, 2019Applicants: SHIMADZU CORPORATION, KAZUSA DNA RESEARCH INSTITUTEInventors: Masaki KANAI, Hiroyuki JIKUYA, Tetsuo OHASHI, Shin NAKAMURA, Osamu OHARA
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Publication number: 20180224442Abstract: To provide a device for operating magnetic particles capable of treating large quantity, and retaining a gel-like medium layer stably, a vessel is formed so that an area perpendicular to a longitudinal direction in a large-diameter part packed with a liquid layer is larger than an area perpendicular to the longitudinal direction in the small-diameter part packed with a gel-like medium layer. Therefore, in the vessel, it is possible to reduce the diameter of the small-diameter part while keeping the capacity of the large-diameter part large. As a result, in the vessel, it is possible to treat large quantity in the liquid layer, and it is possible to retain the gel-like medium layer stably.Type: ApplicationFiled: February 8, 2018Publication date: August 9, 2018Applicant: SHIMADZU CORPORATIONInventors: Masaki KANAI, Hiroyuki JIKUYA, Tetsuo OHASHI, Seiya FUJIWARA
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Patent number: 10029253Abstract: Micro droplets are accurately placed in a reaction well. The reaction well (5) is formed in one surface of a well base (3). A channel base (11) is placed on the well base (3). The channel base (11) has, in its surface joined to the well base (3), a liquid introduction channel (12a) and a reaction well air vent channel (18a). The channel base (11) also has a recess (27) formed opposite to the reaction well (5) and recessed upward from the upper surface of the liquid introduction channel (12a). When viewed from above, a shoulder part (26) of the recess (27) is placed near the connection part between the reaction well (5) and the liquid introduction channel (12a) and is closer to the center of the reaction well (5) than a shoulder part (16) of the reaction well (5).Type: GrantFiled: October 11, 2013Date of Patent: July 24, 2018Assignee: SHIMADZU CORPORATIONInventors: Masakazu Akechi, Masaki Kanai, Takahiro Nishimoto, Nobuhiro Hanafusa
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Publication number: 20180182248Abstract: A traffic control system for a manned vehicle, traveling on one of plural lanes arranged side by side in a mine, and a traffic control device connected with the vehicle. A zone of the lane, on which the vehicle is traveling, is set as a first travel-permitted zone with a travel permission given to the vehicle only. Upon receipt of a request from the vehicle for a travel-permitted zone of another-lane with a travel permission given only to the vehicle on a lane adjacent the lane on which the vehicle is traveling, the traffic control device sets, as the travel-permitted zone of the another-lane, a zone including at least a part of a zone arranged on the adjacent lane side by side with the first travel-permitted zone, and transmits the travel-permitted zone of the another-lane to the vehicle, which the vehicle displays on a display screen.Type: ApplicationFiled: March 9, 2016Publication date: June 28, 2018Inventors: Masaki KANAI, Manabu KATOU, Tomoyuki HAMADA
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Publication number: 20180112207Abstract: A device for manipulating magnetic particles includes a gelled medium layer and liquid layers alternately stacked in a tubular container along a longitudinal direction of the container. A magnetic particle movement portion for moving magnetic particles exists along an inner wall surface of the container, and the magnetic particle movement portion extends along the longitudinal direction of the container. At a portion where the gelled medium layer is loaded, the cross-sectional shape of the container inner wall in a plane perpendicular to the longitudinal direction of the container is non-circular, and the shape of the magnetic particle movement portion in the cross section is a curved shape or an angular shape.Type: ApplicationFiled: January 15, 2015Publication date: April 26, 2018Applicant: SHIMADZU CORPORATIONInventors: Masaki KANAI, Tetsuo OHASHI, Takahiro NISHIMOTO