Abstract: According to a first aspect of the present invention, a method of applying a force to an organism is provided which includes: forming a gas-liquid interface between a liquid, in which an organism is immersed, and a gas in a flow channel or at an end portion of the flow channel after arranging the end portion in the liquid; controlling a vector of a force applied from the gas-liquid interface to the organism; and applying a force to the organism from the gas-liquid interface.

Abstract: A first aspect of the present invention provides a manipulating method of an organism including forming an air bubble in liquid where the organism is immersed, attaching the organism to the air bubble, and controlling an airflow by generating the airflow in the air bubble and manipulating a position of the organism with the airflow.

Abstract: In a first aspect of the present invention, a manipulation method of an organism is provided, comprising: forming an air bubble by introducing gas into liquid in which an organism is submerged; controlling of energy before, during or after the forming of the air bubble, including controlling of difference (E1 - E2) obtained by subtracting, from surface free energy E1 at an interface between the gas and the organism, surface free energy E2 at an interface between the gas and the liquid; and manipulating the organism using the air bubble, by bringing the air bubble into contact with the organism during or after the controlling of energy.

Abstract: A cell manipulation method is provided including culturing cells in a liquid; disposing a flow path through which a gas is able to be introduced in the liquid; forming an air bubble at an end portion of the flow path; and attaching the cells to the air bubble.

Abstract: An article for a living body or a biological sample is provided, the article including a first film and a second film, in which the first film includes an amorphous carbon film in which a proportion of the number of carbon atoms having an sp2-hybrid orbital to a total number of carbon atoms having an sp2-hybrid orbital and carbon atoms having an sp3-hybrid orbital is in a range of 23 to 43 atom % or a titanium-doped amorphous carbon film in which a proportion of the number of titanium atoms to the number of carbon atoms is in a range of 3 to 12 atom %, and the second film includes any one film selected from an amorphous carbon film in which a static contact angle with pure water is 10° or less, a titanium-doped amorphous carbon film in which a proportion of the number of titanium atoms to the number of carbon atoms is less than 3 atom % or greater than 12 atom %, or a titanium-doped amorphous carbon film in which a static contact angle with pure water is 10° or less.

Abstract: A combination of an HCV antigen for inducing an antibody having the activity of inhibiting HCV infection and an optimum adjuvant is discovered, so as to provide an effective HCV vaccine composition. The hepatitis C virus vaccine composition comprises: inactivated viral particles obtained by inactivating infectious hepatitis C virus particles prepared from hepatitis C virus genome that contains sequences encoding NS3 protein, NS4A protein, NS4B protein, NS5A protein and NS5B protein derived from hepatitis C virus JFH1 strain; an oligonucleotide containing unmethylated CpG, according to SEQ ID NO: 5 in the sequence listing; and aluminium hydroxide.

Abstract: To provide a tracheostomy tube which can be easily attached to and detached from an incision site and in which sputum or the like does not readily longer, a tracheostomy tube A includes a lumen body 10 having an airway securing lumen 10b, a connector section 11 formed at the base end portion of the lumen body 10, and a cuff 13 which is formed on the outer circumference of the tip end portion of the lumen body 10 and which can be expanded and contracted. A circumferential wall 10a of the lumen body 10 defines a cuff-expanding lumen 15 which puts the surface portion of the connector section 11 in communication with the inside of the cuff 13. it also defines a suction lumen 14 allowing the surface portion of the connector section 11 to communicate with the surface portion of the lumen body 10. A coating layer exhibiting surface lubricity in moisture is formed on the surface of the tracheostomy tube A and the inner surface of the lumen body 10 in which the airway securing lumen 10b is formed.

Abstract: To provide a tracheostomy tube which can be easily attached to and detached from an incision site and in which sputum or the like does not readily longer, a tracheostomy tube A includes a lumen body 10 having an airway securing lumen 10b, a connector section 11 formed at the base end portion of the lumen body 10, and a cuff 13 which is formed on the outer circumference of the tip end portion of the lumen body 10 and which can be expanded and contracted. A circumferential wall 10a of the lumen body 10 defines a cuff-expanding lumen 15 which puts the surface portion of the connector section 11 in communication with the inside of the cuff 13. it also defines a suction lumen 14 allowing the surface portion of the connector section 11 to communicate with the surface portion of the lumen body 10. A coating layer exhibiting surface lubricity in moisture is formed on the surface of the tracheostomy tube A and the inner surface of the lumen body 10 in which the airway securing lumen 10b is formed.