Abstract: Provided is an agent having an action on a transcellular ion transporter in the intestinal tract, the agent containing a bacterium of the genus Bifidobacterium or the genus Lactobacillus, or a treated product thereof, with the proviso that the case where the ion transporter is a chloride channel and the action is inhibition; the case where the ion transporter is Na+K+Cl? cotransporter (NKCC1) and the action is inhibition; the case where the bacterium is Bifidobacterium infantis 35624; and the case where the bacterium is Lactobacillus salivarius UCC118 are excluded. The agent of the present invention is useful in activation of chloride channels, prevention or treatment of renal diseases, and/or promotion of defecation, and therefore, usable as a medicament, a supplement, etc.

Abstract: An object of the present invention is to provide an agent for preventing or treating a fat-associated disease and/or inflammation. The present invention provides an agent for preventing or treating a fat-associated disease and/or inflammation, the agent comprising a Faecalibacterium bacterium or a processed product thereof.

Abstract: An object of the present invention is to provide an agent for preventing or treating small intestinal injury induced by an NSAID with a half-life of less than 14 hours and a proton pump inhibitor. The present invention provides an agent for preventing or treating small intestinal injury induced by a non-steroidal anti-inflammatory drug with a half-life of less than 14 hours and a proton pump inhibitor, and an agent for preventing or treating a fat-associated disease and/or inflammation accompanying the small intestinal injury, the agents comprising a Bifidobacterium bacterium or a processed product thereof.

Abstract: An object of the present invention is to provide an agent for preventing or treating a fat-associated disease and/or inflammation. The present invention provides an agent for preventing or treating a fat-associated disease and/or inflammation, the agent comprising a Faecalibacterium bacterium or a processed product thereof.

Abstract: An object of the present invention is to provide an agent for preventing or treating small intestinal injury induced by an NSAID with a half-life of less than 14 hours and a proton pump inhibitor. The present invention provides an agent for preventing or treating small intestinal injury induced by a non-steroidal anti-inflammatory drug with a half-life of less than 14 hours and a proton pump inhibitor, and an agent for preventing or treating a fat-associated disease and/or inflammation accompanying the small intestinal injury, the agents comprising a Bifidobacterium bacterium or a processed product thereof.

Abstract: An object of the present invention is to provide an agent for preventing or treating small intestinal injury induced by a non-steroidal anti-inflammatory drug and a proton pump inhibitor. The present invention provides an agent for preventing or treating small intestinal injury induced by a non-steroidal anti-inflammatory drug and a proton pump inhibitor, and an agent for preventing or treating a fat-associated disease and/or inflammation accompanying the small intestinal injury, the agents comprising Bifidobacterium bifidum, Bifidobacterium longum or Bifidobacterium infantis or a processed product thereof.

Abstract: Provided is an agent having an action on a transcellular ion transporter in the intestinal tract, the agent containing a bacterium of the genus Bifidobacterium or the genus Lactobacillus, or a treated product thereof, with the proviso that the case where the ion transporter is a chloride channel and the action is inhibition; the case where the ion transporter is Na+K+Cl? cotransporter (NKCC1) and the action is inhibition; the case where the bacterium is Bifidobacterium infantis 35624; and the case where the bacterium is Lactobacillus salivarius UCC118 are excluded. The agent of the present invention is useful in activation of chloride channels, prevention or treatment of renal diseases, and/or promotion of defecation, and therefore, usable as a medicament, a supplement, etc.

Abstract: A hypoglycemic effect enhancer for enhancing the activity of an ?-glucosidase inhibitor, the enhancer comprising at least one kind of bacteria selected from the group consisting of bifidobacteria, lactic acid bacteria, saccharifying bacteria, and butyric acid bacteria.

Abstract: A hypoglycemic effect enhancer for enhancing the activity of an ?-glucosidase inhibitor, the enhancer comprising at least one kind of bacteria selected from the group consisting of bifidobacteria, lactic acid bacteria, saccharifying bacteria, and butyric acid bacteria.