Patents by Inventor Masaki Tomimoto

Masaki Tomimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrimidinyl-thiophene kinase modulators
    Patent number: 7977481
    Abstract: The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: July 12, 2011
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Chixu Chen, Stefan N. Gradl, Stephanie Hopkins, Ruo W. Steensma, Masaki Tomimoto, Mark E. Wilson
  • Pyrimidinyl-Thiophene Kinase Modulators
    Publication number: 20100305128
    Abstract: The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: August 6, 2010
    Publication date: December 2, 2010
    Inventors: William D. Arnold, Chixu Chen, Stefan N. Gradl, Stephanie A. Hopkins, Ruo W. Steensma, Masaki Tomimoto, Mark E. Wilson
  • Pyrimidinyl-thiophene kinase modulators
    Patent number: 7803806
    Abstract: The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: November 2, 2006
    Date of Patent: September 28, 2010
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Chixu Chen, Stefan N. Gradl, Stephanie A. Hopkins, Ruo W. Steensma, Masaki Tomimoto, Mark E. Wilson
  • Hepatitis C virus polymerase inhibitors
    Publication number: 20080200512
    Abstract: The invention provides a compound of formula: and methods for making and using the same, where R1 and R2 are independently hydrogen, C1-6 alkyl or C1-6 haloalkyl; R3 is hydrogen, halogen, C1-6 alkyl or C1-6 alkoxy; R4 is hydrogen or halogen; and R5 is a mono- or di-amino acid moiety, a succinic acid moiety, a urea moiety, or a derivative thereof. The invention also provides pharmaceutical compositions comprising a compound of formula I, and methods for making and using the same.
    Type: Application
    Filed: February 14, 2008
    Publication date: August 21, 2008
    Inventors: Jeffrey Mark Blaney, Normand Hebert, Stephanie Ann Hopkins, Elizabeth A. Jefferson, Masaki Tomimoto
  • PYRIMIDINYL-THIOPHENE KINASE MODULATORS
    Publication number: 20070117800
    Abstract: The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: November 2, 2006
    Publication date: May 24, 2007
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: William Arnold, Chixu Chen, Stefan Gradl, Stephanie Hopkins, Ruo Steensma, Masaki Tomimoto, Mark Wilson
  • Compound libraries and methods for drug discovery
    Publication number: 20040265909
    Abstract: The present invention provides compound libraries that can be rapidly and efficiently synthesized for use in lead discovery and design, and can be easily expanded for further drug discovery. The present invention also provides methods of using such compound libraries to design and identify novel drug leads.
    Type: Application
    Filed: April 9, 2004
    Publication date: December 30, 2004
    Inventors: Jeff Blaney, Ian McDonald, Masaki Tomimoto
  • Crystals and structures of spleen tyrosine kinase SYKKD
    Publication number: 20040253178
    Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of SYKKD and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of SYKKD, and compounds and compositions that affect SYK activity.
    Type: Application
    Filed: December 17, 2003
    Publication date: December 16, 2004
    Inventors: Shane Atwell, Jorg Hendle, Sean Grant Buchanan, Ingeborg Feil, Marijane Russell, John Badger, Masaki Tomimoto, Michael J. Sauder