Patents by Inventor Masaki Tsushima
Masaki Tsushima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170077493Abstract: A method for forming a positive electrode for a thin film lithium-ion rechargeable battery includes forming a positive electrode power collection layer, forming a first positive electrode active material layer by covering the positive electrode power collection layer with a first positive electrode active material that contains lithium cobalt oxide, forming a second positive electrode active material layer that has a thickness of 20 nm or greater and 60 nm or less by covering the first positive electrode active material layer with a second positive electrode active material that contains aluminum and lithium cobalt oxide, and heating a lamination body that includes the positive electrode power collection layer, the first positive electrode active material layer, and the second positive electrode active material layer.Type: ApplicationFiled: September 8, 2016Publication date: March 16, 2017Inventors: Shunsuke SASAKI, Akiyoshi SUZUKI, Takehito JINBO, Masaki TSUSHIMA, Kazutoshi TAKAHASHI
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Publication number: 20160152653Abstract: This invention relates to novel aminoglycoside antibiotics, which have potent antimicrobial activity against bacteria, which induce infectious diseases, particularly MRSA, and has no significant nephrotoxicity, and process for producing them. More particularly, the present invention relates to compounds represented by formula (Ia) or their pharmacologically acceptable salts or solvates, or their diastereomer mixtures, antimicrobial agents comprising them, and a process for producing them.Type: ApplicationFiled: December 30, 2015Publication date: June 2, 2016Inventors: Yoshihiko KOBAYASHI, Yoshihisa AKIYAMA, Takeshi MURAKAMI, Nobuto MINOWA, Masaki TSUSHIMA, Yukiko HIRAIWA, Shoichi MURAKAMI, Mitsuhiro ABE, Kazushige SASAKI, Shigeru HOSHIKO, Toshiaki MIYAKE, Yoshiaki TAKAHASHI, Daishiro IKEDA
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Patent number: 9260465Abstract: This invention relates to novel aminoglycoside antibiotics, which have potent antimicrobial activity against bacteria, which induce infectious diseases, particularly MRSA, and has no significant nephrotoxicity, and process for producing them. More particularly, the present invention relates to compounds represented by formula (Ia) or their pharmacologically acceptable salts or solvates, or their diastereomer mixtures, antimicrobial agents comprising them, and a process for producing them.Type: GrantFiled: August 20, 2013Date of Patent: February 16, 2016Assignees: MEIJI SEIKA PHARMA CO., LTD., MICROBIAL CHEMISTRY RESEARCH FOUNDATIONInventors: Yoshihiko Kobayashi, Yoshihisa Akiyama, Takeshi Murakami, Nobuto Minowa, Masaki Tsushima, Yukiko Hiraiwa, Shoichi Murakami, Mitsuhiro Abe, Kazushige Sasaki, Shigeru Hoshiko, Toshiaki Miyake, Yoshiaki Takahashi, Daishiro Ikeda
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Publication number: 20130345411Abstract: This invention relates to novel aminoglycoside antibiotics, which have potent antimicrobial activity against bacteria, which induce infectious diseases, particularly MRSA, and has no significant nephrotoxicity, and process for producing them. More particularly, the present invention relates to compounds represented by formula (Ia) or their pharmacologically acceptable salts or solvates, or their diastereomer mixtures, antimicrobial agents comprising them, and a process for producing them.Type: ApplicationFiled: August 20, 2013Publication date: December 26, 2013Applicants: MICROBIAL CHEMISTRY RESEARCH FOUNDATION, MEIJI SEIKA PHARMA CO., LTD.Inventors: Yoshihiko KOBAYASHI, Yoshihisa AKIYAMA, Takeshi MURAKAMI, Nobuto MINOWA, Masaki TSUSHIMA, Yukiko HIRAIWA, Shoichi MURAKAMI, Mitsuhiro ABE, Kazushige SASAKI, Shigeru HOSHIKO, Toshiaki MIYAKE, Yoshiaki TAKAHASHI, Daishiro IKEDA
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Patent number: 8541394Abstract: This invention relates to novel aminoglycoside antibiotics, which have potent antimicrobial activity against bacteria, which induce infectious diseases, particularly MRSA, and has no significant nephrotoxicity, and process for producing them. More particularly, the present invention relates to compounds represented by formula (Ia) or their pharmacologically acceptable salts or solvates, or their diastereomer mixtures, antimicrobial agents comprising them, and a process for producing them.Type: GrantFiled: March 7, 2012Date of Patent: September 24, 2013Assignees: Meiji Seika Pharma Co., Ltd., Microbial Chemistry Research FoundationInventors: Yoshihiko Kobayashi, Yoshihisa Akiyama, Takeshi Murakami, Nobuto Minowa, Masaki Tsushima, Yukiko Hiraiwa, Shoichi Murakami, Mitsuhiro Abe, Kazushige Sasaki, Shigeru Hoshiko, Toshiaki Miyake, Yoshiaki Takahashi, Daishiro Ikeda
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Publication number: 20120165283Abstract: This invention relates to novel aminoglycoside antibiotics, which have potent antimicrobial activity against bacteria, which induce infectious diseases, particularly MRSA, and has no significant nephrotoxicity, and process for producing them. More particularly, the present invention relates to compounds represented by formula (Ia) or their pharmacologically acceptable salts or solvates, or their diastereomer mixtures, antimicrobial agents comprising them, and a process for producing them.Type: ApplicationFiled: March 7, 2012Publication date: June 28, 2012Inventors: Yoshihiko Kobayashi, Yoshihisa Akiyama, Takeshi Murakami, Nobuto Minowa, Masaki Tsushima, Yukiko Hiraiwa, Shoichi Murakami, Mitsuhiro Abe, Kazushige Sasaki, Shigeru Hoshiko, Toshiaki Miyake, Yoshiaki Takahashi, Daishiro Ikeda
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Patent number: 8148504Abstract: This invention relates to novel aminoglycoside antibiotics, which have potent antimicrobial activity against bacteria, which induce infectious diseases, particularly MRSA, and has no significant nephrotoxicity, and process for producing them. More particularly, the present invention relates to compounds represented by formula (Ia) or their pharmacologically acceptable salts or solvates, or their diastereomer mixtures, antimicrobial agents comprising them, and a process for producing them.Type: GrantFiled: June 1, 2007Date of Patent: April 3, 2012Assignees: Meiji Seika Pharma Co., Ltd., Microbial Chemistry Research FoundationInventors: Yoshihiko Kobayashi, Yoshihisa Akiyama, Takeshi Murakami, Nobuto Minowa, Masaki Tsushima, Yukiko Hiraiwa, Shoichi Murakami, Mitsuhiro Abe, Kazushige Sasaki, Shigeru Hoshiko, Toshiaki Miyake, Yoshiaki Takahashi, Daishiro Ikeda
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Publication number: 20090186841Abstract: This invention relates to novel aminoglycoside antibiotics, which have potent antimicrobial activity against bacteria, which induce infectious diseases, particularly MRSA, and has no significant nephrotoxicity, and process for producing them. More particularly, the present invention relates to compounds represented by formula (Ia) or their pharmacologically acceptable salts or solvates, or their diastereomer mixtures, antimicrobial agents comprising them, and a process for producing them.Type: ApplicationFiled: June 1, 2007Publication date: July 23, 2009Inventors: Yoshihiko Kobayashi, Yoshihisa Akiyama, Takeshi Murakami, Nobuto Minowa, Masaki Tsushima, Yukiko Hiraiwa, Shoichi Murakami, Mitsuhiro Abe, Kazushige Sasaki, Shigeru Hoshiko, Toshiaki Miyake, Yoshiaki Takahashi, Daishiro Ikeda
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Patent number: 6916822Abstract: A medicament useful for preventive and/or therapeutic treatment of nerve system diseases which comprises, as an active ingredient, a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof: wherein, X represents a group represented by the following general formula (II), (III), (IV), (V), or (VI), “A” represents a saturated or unsaturated 3- to 6-membered carbocyclic group and the like, “B” represents CH2 and the like, “n” represents 0 to 2, R1 represents a hydrogen atom, a halogen atom and the like, R2, R3, and R7 to R14 represent a hydrogen atom, a lower alkyl group which may be substituted and the like, R4 represents a hydrogen atom, a lower alkyl group which may be substituted and the like, R5 represents a hydrogen atom, a halogen atom and the like, R6 represents a saturated or unsaturated monocyclic or bicyclic carbocyclic group and the like, and R5 and R6, R7 and R8, R9 and R10, or R11 and R12 may bind to each other to form a cyclic structure.Type: GrantFiled: February 16, 2001Date of Patent: July 12, 2005Assignee: Meiji Seika Kaisha, Ltd.Inventors: Masaki Tsushima, Kaori Tadauchi, Kenji Asai, Naoko Miike, Masako Imai, Toshiaki Kudo
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Publication number: 20050148583Abstract: A medicament useful for preventive and/or therapeutic treatment of nerve system diseases which comprises, as an active ingredient, a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof: wherein, X represents a group represented by the following general formula (II), (III), (IV), (V), or (VI), “A” represents a saturated or unsaturated 3- to 6-membered carbocyclic group and the like, “B” represents CH2 and the like, “n” represents 0 to 2, R1 represents a hydrogen atom, a halogen atom and the like, R2, R3, and R7 to R14 represent a hydrogen atom, a lower alkyl group which may be substituted and the like, R4 represents a hydrogen atom, a lower alkyl group which may be substituted and the like, R5 represents a hydrogen atom, a halogen atom and the like, R6 represents a saturated or unsaturated monocyclic or bicyclic carbocyclic group and the like, and R5 and R6, R7 and R8, R9 and R10, or R11 and R12 may bind to each other to form a cyclic structure.Type: ApplicationFiled: March 2, 2005Publication date: July 7, 2005Applicant: Meiji Seika Kaisha, Ltd.Inventors: Masaki Tsushima, Kaori Tadauchi, Kenji Asai, Naoko Miike, Masako Imai, Toshiaki Kudo
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Patent number: 6790854Abstract: A substance having affinity for an opioid &dgr; receptor, which is represented by the following general formula (I): wherein, X represents a group of the general formula: —CO—N(R5)(R6) (II) and the like, n represents 1 to 3, R1 and R2 represent a hydrogen atom, a halogen atom, a lower alkyl group and the like, R3 represents a hydrogen atom, a halogen atom, a lower alkyl group and the like, R4 represents a saturated or unsaturated monocyclic or bicyclic carbocyclic group and the like, R5 to R12 represent a hydrogen atom, a lower alkyl group and the like, and R3 and R4, R5 and R6, R7 or R8 and R9 and R10 may bind to each other to form a cyclic structure, and a medicament useful for preventive and/or therapeutic treatment of central nervous system diseases and peripheral nervous system diseases comprising the substance as an active ingredient.Type: GrantFiled: March 13, 2003Date of Patent: September 14, 2004Assignee: Meiji Seika Kaisha, Ltd.Inventors: Masaki Tsushima, Kaori Tadauchi, Kenji Asai, Naoko Miike, Toshiaki Kudo
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Publication number: 20030176693Abstract: A substance having affinity for an opioid &dgr; receptor, which is represented by the following general formula (I): 1Type: ApplicationFiled: March 13, 2003Publication date: September 18, 2003Inventors: Masaki Tsushima, Kaori Tadauchi, Kenji Asai, Naoko Miike, Toshiaki Kudo
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Publication number: 20030171370Abstract: A medicament useful for preventive and/or therapeutic treatment of nerve system diseases which comprises, as an active ingredient, a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof: 1Type: ApplicationFiled: December 3, 2002Publication date: September 11, 2003Inventors: Masaki Tsushima, Kaori Tadauchi, Kenji Asai, Naoko Miike, Masako Imai, Toshiaki Kudo
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Patent number: 5663162Abstract: Compounds represented by the following formula (I), that is, cephem derivatives having substituted or unsubstituted imidazo[5,1-b]thiazolium-6-yl as a substituent at the 3-position of the cephem ring: ##STR1## wherein X represents CH or N, R.sup.1 represents H, alkyl, alkenyl or the like, and R.sup.2, R.sup.3, R.sup.4 and R.sup.5 represent H, alkyl, carbamoyl, amino or the like. The above compounds have excellent antibacterial activity, and useful as medicines for the treatment of various infectious diseases caused by bacteria.Type: GrantFiled: July 25, 1995Date of Patent: September 2, 1997Assignee: Meiji Seika Kabushiki KaishaInventors: Kunio Atsumi, Eijiro Umemura, Yuko Kano, Sohjiro Shiokawa, Toshiaki Kudo, Masaki Tsushima, Katsuyoshi Iwamatsu, Atsushi Tamura, Seiji Shibahara
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Patent number: 5661144Abstract: Compounds represented by the following formula (I), that is, cephem derivatives having substituted or unsubstituted 3-(imidazo[5,1-b]thiazolium-6-yl)-1-propenyl as a substituent at the 3-position of the cephem ring: ##STR1##Type: GrantFiled: June 28, 1996Date of Patent: August 26, 1997Assignee: Meiji Seika Kabushiki KaishaInventors: Masaki Tsushima, Kunio Atsumi, Katsuyoshi Iwamatsu, Atsushi Tamura
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Patent number: 5607927Abstract: An aminothiazolyl- or aminothiadiazolyl-cephalosporin derivative represented by the following general formula (I) which has a condensed-ring thio group as a 3-positioned substituent group that contains a thiazolylthio group, an oxazolylthio group or a heterocyclic ring thereof as one of the ring components. The compound according to the present invention has excellent activities to inhibit growth of various bacteria, especially Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA), and therefore, the antibacterial agent comprising, as an active ingredient, the inventive compound can be used as a therapeutic drug for the treatment of various bacterial infections.Type: GrantFiled: February 7, 1995Date of Patent: March 4, 1997Assignee: Meiji Seika Kaisha, Ltd.Inventors: Masaki Tsushima, Katsuyoshi Iwamatsu, Atsushi Tamura, Seiji Shibahara
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Patent number: 5464829Abstract: A cephalosporin derivative having a quaternary salt type substituent group at the 3-position, represented by formula (I): ##STR1## wherein X is a carbon atom or a nitrogen atom; Y is a sulfur atom, an oxygen atom or a nitrogen atom substituted with a substituted or unsubstituted lower alkyl group; R.sup.1 is a hydrogen atom, a lower alkyl group or a substituted lower alkyl group; R.sup.2 is a lower alkyl group, a substituted lower alkyl group, a lower alkylene group or a substituted lower alkylene group; and A is an unsaturated six-membered heterocyclic ring containing at least one nitrogen atom, or a pharmaceutically acceptable salt thereof is disclosed. The derivatives have excellent antibacterial activities and can be used as a drug for the treatment of various bacterial infections.Type: GrantFiled: December 16, 1993Date of Patent: November 7, 1995Assignee: Meiji Seika Kaisha Ltd.Inventors: Masaki Tsushima, Yuko Kano, Katsuyoshi Iwamatsu, Atsushi Tamura, Seiji Shibahara
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Patent number: 5461044Abstract: As new antibacterial agent are provided cephalosporin derivatives having a general formula (I): ##STR1## wherein R.sup.1 is a hydrogen atom, a lower alkyl group or a substituted lower alkyl group, R.sup.2 is a hydrogen atom or an ester-forming group easily cleavable by an esterase present in the digestive tracts, R.sup.3 and R.sup.4 may be the same and each is independently a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkenyl group, hydroxyl group, amino group or a lower alkoxy group, and a pharmaceutically acceptable salt thereof.The cephalosporin derivative of formula (I) is useful as an orally or injectably administrable cephalosporin derivative which exhibits in combination a high antibacterial activity and a favorable characteristic capable of giving a high concentration of this compound in blood when administered.Type: GrantFiled: January 5, 1995Date of Patent: October 24, 1995Assignee: Meiji Seika Kaisha, Ltd.Inventors: Masaki Tsushima, Katsuyoshi Iwamatsu, Atsushi Tamura, Seiji Shibahara
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Patent number: 5032438Abstract: An adhesive tape for die bonding is disclosed, comprising a release film having a release layer on at least one side of a support and an adhesive layer attached to said release layer, wherein the exposed surface of said adhesive layer is a mirror-like surface having an average roughness on center line (Ra) of not more than 2.5 .mu.m and a maximal height (Rmax) of not more than 20 .mu.m.Type: GrantFiled: May 25, 1989Date of Patent: July 16, 1991Assignee: Tomoegawa Paper Co., Ltd.Inventors: Yukinori Sakumoto, Atsushi Koshimura, Masaki Tsushima
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Patent number: 4933219Abstract: An adhesive tape for die bonding is disclosed, comprising a continuous tape wound on a reel, the continuous tape having a structure that an adhesive layer composed mainly of a filler and a binder comprised of an epoxy resin and a polyester resin is laminated on a release film. According to the adhesive tape for die bonding of the invention, bonding of semiconductor elements can be attained with good workability and high reliability by very easily handling of the adhesive tape.Type: GrantFiled: March 20, 1989Date of Patent: June 12, 1990Assignee: Tomoegawa Paper Co., Ltd.Inventors: Yukinori Sakumoto, Atsushi Koshimura, Hiroshi Matsushita, Masaki Tsushima