Abstract: A control device includes a control IC that receives power supply from a power source unit activated by a first signal, and that is configured to control driving of the power source unit, a first signal acquisition unit configured to acquire the first signal, a detection unit configured to detect rising and falling of the first signal, a second signal output unit configured to output a second signal when the falling of the first signal is detected by the detection unit, and a lowering unit configured to lower, according to the second signal output from the second signal output unit, a voltage value of a terminal of the power source unit, to which the first signal is to be input, to a predetermined value or less for a predetermined period of time set in advance.

Abstract: A control device includes a control IC that receives power supply from a power source unit activated by a first signal, and that is configured to control driving of the power source unit, a first signal acquisition unit configured to acquire the first signal, a detection unit configured to detect rising and falling of the first signal, a second signal output unit configured to output a second signal when the falling of the first signal is detected by the detection unit, and a lowering unit configured to lower, according to the second signal output from the second signal output unit, a voltage value of a terminal of the power source unit, to which the first signal is to be input, to a predetermined value or less for a predetermined period of time set in advance.

Abstract: A head suspension 11 includes a load beam 17 having a base plate 13, a hinge part 15 resiliently supported by the base plate, and a rigid part 14 joined with the hinge part, a reinforcing plate 25 joined with the rigid part at a portion proximal to the hinge part, and a bend 17c on the load beam formed by bending the load beam toward the reinforcing plate along an edge 25a of the reinforcing plate. Only by accurately joining the reinforcing plate with the load beam in a sway direction (a widthwise direction of the head suspension), the load beam is easily and properly bent without torsion to form the bend 17c along the edge of the reinforcing plate that defines a bending strength boundary.

Abstract: A suspension is provided with a base plate, load beam, and flexure. The base plate includes a boss portion, a first region situated on a side closer to a slider with respect to a center of the boss portion, and a second region situated on a side more remote from the slider. A pair of first projections are formed in the first region. A pair of second projections are formed in the second region. The projections project in the thickness direction of the base plate. The boss portion is inserted into a hole in an actuator arm, and the projections contact a suspension support portion of the actuator arm. The boss portion is pressurized from inside to be enlarged, whereby the base plate is fixed to the inner peripheral surface of the hole of the actuator arm.

Abstract: A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided. A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.

Abstract: A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided. A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.

Abstract: A head suspension 11 includes a load beam 17 having a base plate 13, a hinge part 15 resiliently supported by the base plate, and a rigid part 14 joined with the hinge part, a reinforcing plate 25 joined with the rigid part at a portion proximal to the hinge part, and a bend 17c on the load beam formed by bending the load beam toward the reinforcing plate along an edge 25a of the reinforcing plate. Only by accurately joining the reinforcing plate with the load beam in a sway direction (a widthwise direction of the head suspension), the load beam is easily and properly bent without torsion to form the bend 17c along the edge of the reinforcing plate that defines a bending strength boundary.

Abstract: A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided. A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.

Abstract: The present invention relates to a 2-phenylthiophene derivative or a salt thereof, wherein the thiophene ring is substituted with a carboxyl group or the like and the benzene ring has an electron-withdrawing group such as a cyano group and an electron-donating group such as a substituted alkoxy group at the same time. Since the compound of the invention has good xanthine oxidase-inhibitory action and uric acid-lowering action and does not have a structure derived from nucleic acid, the compound has advantages of high safety and excellent effects as compared with conventional compounds and is useful as a therapeutic or preventive agent for hyperuricemia, gout, inflammatory bowel diseases, diabetic kidney diseases, diabetic retinopathy, or the like.

Abstract: A suspension is provided with a base plate, load beam, and flexure. The base plate includes a boss portion, a first region situated on a side closer to a slider with respect to a center of the boss portion, and a second region situated on a side more remote from the slider. A pair of first projections are formed in the first region. A pair of second projections are formed in the second region. The projections project in the thickness direction of the base plate. The boss portion is inserted into a hole in an actuator arm, and the projections contact a suspension support portion of the actuator arm. The boss portion is pressurized from inside to be enlarged, whereby the base plate is fixed to the inner peripheral surface of the hole of the actuator arm.

Abstract: A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided. A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.

Abstract: The present invention relates to a 2-phenylthiophene derivative or a salt thereof, wherein the thiophene ring is substituted with a carboxyl group or the like and the benzene ring has an electron-withdrawing group such as a cyano group and an electron-donating group such as a substituted alkoxy group at the same time. Since the compound of the invention has good xanthine oxidase-inhibitory action and uric acid-lowering action and does not have a structure derived from nucleic acid, the compound has advantages of high safety and excellent effects as compared with conventional compounds and is useful as a therapeutic or preventive agent for hyperuricemia, gout, inflammatory bowel diseases, diabetic kidney diseases, diabetic retinopathy, or the like.

Abstract: Obtaining the crystal of 4,6-dimethyl-4?-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]nicotinanilide having excellent activity of inhibiting Ca2+ release-activated Ca2+ channel and suppressing IL-2 production to find that the compound includes the presence of two types of polymorphic crystals and that any of the crystals is preferable as a raw material for producing pharmaceutical compositions.

Abstract: Obtaining the crystal of 4,6-dimethyl-4?-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]nicotinanilide having excellent activity of inhibiting Ca2+ release-activated Ca2+ channel and suppressing IL-2 production to find that the compound includes the presence of two types of polymorphic crystals and that any of the crystals is preferable as a raw material for producing pharmaceutical compositions.

Abstract: A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided. A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.

Abstract: An azole derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, having both of a leukotriene antagonistic effect and a thromboxane A2 antagonistic effect and being useful in preventing or treating allergic diseases, ischemic heart diseases or ischemic brain diseases, and a medicinal composition containing the same as the active ingredient, wherein R.sup.1 and R.sup.2 may be the same or different and represent each hydrogen, cycloalkyl, etc., or R.sup.1 and R.sup.2 together with (a) may form a fused ring (b) or (c) which may be substituted by optionally substituted lower alkyl, amino, etc.; R.sup.3, R.sup.6, R.sup.7, R.sup.8 may be the same or different and represent each hydrogen, amino, etc.; R.sup.4 represents cyano, tetrazolyl, --COOR.sup.9, etc.; R.sup.5 represents hydrogen or lower alkyl; D represents optionally substituted lower alkylene; X and Z may be the same or different and represent each oxygen or sulfur; Y represents --N.dbd. or --CH.dbd.

Abstract: A compound of the formula (I) or its salt and a process for producing the compounds; The compounds have the effect to dilate neophrovascular tracts; ##STR1## Wherein ##STR2## represents the formula ##STR3## (wherein R.sup.4 is a hydrogen atom or lower alkylsulfonyl); R.sup.1 is hydrogen, lower alkyl, hydroxyl, halogen, amino, or lower acylamino;R.sup.2 is hydrogen, lower alkyl, hydroxyl, amino, or lower alkylsulfonylamino;R.sup.3 is hydrogen, lower alkyl, or hydroxyl;R is hydrogen or halogen;with the proviso that when R.sup.1 is hydroxyl, there is no case that all of R.sup.2, R.sup.3 and R are hydrogens, and further with the proviso that when R is hydrogen, A excludes ##STR4## or a salt thereof.

Abstract: This invention provides certain novel substituted tetrahydroisoquinoline opticulisomers of the formula: ##STR1## wherein A represents the formula ##STR2## wherein R is hydrogen or halogen; R.sup.1 is hydrogen, lower alkyl, hydroxyl, halogen, amino, or lower acylamino;R.sup.2 is hydrogen, lower alkyl, hydroxyl, amino, or lower alkylsulfonylamino;R.sup.3 is hydrogen, lower alkyl, or hydroxyl;R.sup.4 is a hydrogen atom or a lower alkylsulfonyl;with the proviso that when R.sup.1 is hydroxyl, R.sup.2 and R.sup.3 are all not hydrogen, or salts thereof.

Abstract: A cephalosporin compound represented by the general formula: ##STR1## This compound exhibits a high antimicrobial activity.

Abstract: This invention provides the single species (-)-(S)-4-(3,4-dihydroxyphenyl)-7, 8-dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrochloride hydrate, which is useful as a nephrovascular dilator.