Patents by Inventor Masako Taniike

Masako Taniike has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7238718
    Abstract: An object of the present invention is to provide a method which is able to prevent or improve the progress of myolytic diseases such as muscular dystrophy. Such an object is able to be solved by a method where an effective dose of an inhibitor for hematopoietic prostaglandin D synthase (H-PGDS) or an antagonist to prostaglandin D receptor is administered to a patient who needs it. The present invention also provides a method for screening compounds which are able to prevent the progress of myolytic diseases and to improve it using human H-PGDS overexpressed transgenic mice.
    Type: Grant
    Filed: August 17, 2004
    Date of Patent: July 3, 2007
    Assignees: Osaka Bioscience Institute, Riken
    Inventors: Yoshihiro Urade, Naomi Eguchi, Kosuke Aritake, Yo Sato, Masako Taniike, Ikuko Mori, Masashi Miyano
  • Publication number: 20050272767
    Abstract: An object of the present invention is to provide a method which is able to prevent or improve the progress of myolytic diseases such as muscular dystrophy. Such an object is able to be solved by a method where an effective dose of an inhibitor for hematopoietic prostaglandin D synthase (H-PGDS) or an antagonist to prostaglandin D receptor is administered to a patient who needs it. The present invention also provides a method for screening compounds which are able to prevent the progress of myolytic diseases and to improve it using human H-PGDS overexpressed transgenic mice.
    Type: Application
    Filed: August 17, 2004
    Publication date: December 8, 2005
    Applicant: Osaka Bioscience Institute and RIKEN
    Inventors: Yoshihiro Urade, Naomi Eguchi, Kosuke Aritake, Yo Sato, Masako Taniike, Ikuko Mori, Masashi Miyano
  • Publication number: 20050227984
    Abstract: There are provided a compound for treatment or prevention of brain injury caused by diseases such as cerebrovascular disorder, brain degenerative disease and demyelinating disease and a method for screening the same. Brain injury in which prostaglandin D2 is participated is treated or prevented by inhibition of hematopoietic prostaglandin D synthase induced in microglia cell or macrophage of brain injury area by diseases such as cerebrovascular disorder, brain degenerative disease or demyelinating disease or by inhibition of activation of prostaglandin D receptor expressed in astroglia cell around the injured area. There is also provided a method of testing those pharmaceutical substances using a transgenic mouse in which human hematopoietic prostaglandin D synthase is expressed in large amounts.
    Type: Application
    Filed: May 31, 2005
    Publication date: October 13, 2005
    Inventors: Yoshihiro Urade, Naomi Eguchi, Kosuke Aritake, Yo Sato, Keiichi Kadoyama, Masako Taniike
  • Publication number: 20050222235
    Abstract: There are provided a compound for treatment or prevention of brain injury caused by diseases such as cerebrovascular disorder, brain degenerative disease and demyelinating disease and a method for screening the same. Brain injury in which prostaglandin D2 is participated is treated or prevented by inhibition of hematopoietic prostaglandin D synthase induced in microglia cell or macrophage of brain injury area by diseases such as cerebrovascular disorder, brain degenerative disease or demyelinating disease or by inhibition of activation of prostaglandin D receptor expressed in astroglia cell around the injured area. There is also provided a method of testing those pharmaceutical substances using a transgenic mouse in which human hematopoietic prostaglandin D synthase is expressed in large amounts.
    Type: Application
    Filed: July 14, 2003
    Publication date: October 6, 2005
    Inventors: Yoshihiro Urade, Naomi Eguchi, Kosuke Aritake, Yo Sato, Keiichi Kadoyama, Masako Taniike