Abstract: The present invention relates to a composition for immunostimulation useful for promoting IgA and secretory component productions in mucosal tissues, comprising, alone or in combination, a cell of bifidobacterium belonging to Bifidobacterium bifidum or a processed product thereof, wherein the bifidobacterium has an activity to stimulate secretory component production and a high activity to stimulate IgA production, for example, it is a Bifidobacterium bifidum OLB 6377 strain or Bifidobacterium bifidum OLB 6378 strain.

Abstract: An artificial nipple for an experimental animal can include a replaceable duct in a nipple and a structure that prevents liquid from accumulating in the nipple except in the nipple tip and the duct. The artificial nipple can be configured to prevent liquid from accumulating by filling the nipple with an elastic member or by forming the nipple with an elastic member integrally with an outer wall of the nipple.

Abstract: The present invention relates to a composition for immunostimulation useful for promoting IgA and secretory component productions in mucosal tissues, comprising, alone or in combination, a cell of bifidobacterium belonging to Bifidobacterium bifidum or a processed product thereof, wherein the bifidobacterium has an activity to stimulate secretory component production and a high activity to stimulate IgA production, for example, it is a Bifidobacterium bifidum OLB 6377 strain or Bifidobacterium bifidum OLB 6378 strain.

Abstract: The present invention provides agents for alleviating symptoms resulting from inflammation, which have an activity to alleviate inflammatory symptoms caused by bacterial infection, particularly accumulation of body fluid such as bronchocavemous plasma exudation, ascites, etc., at the inflammatory site, or excessive increase of blood neutrophils; symptoms resulting from inflammation caused by bacterial infection, particularly accumulation of body fluid such as bronchocavemous plasma exudation ascites, etc., at the inflammatory site, or excessive increase of blood neutrophils, can be alleviated effectively by ingesting or administering orally or parenterally a composition containing human-type lactoferrin as an effective component.

Abstract: It is intended to provide an artificial nipple, whereby a liquid feed or a test solution can be voluntarily and orally given to experimental animals with a need for feeding such as mouse infants, a feeding bottle appropriately usable in combination with the nipple, a device for feeding a liquid comprising them, and a method of feeding a liquid. The artificial nipple is characterized by having a replaceable duct therein and having a structure preventing a liquid from piling up in the nipple except in the nipple tip and the duct, while the feeding bottle is characterized by having a replaceable tube therein.

Abstract: The present invention provides agents for alleviating symptoms resulting from inflammation, which have an activity to alleviate inflammatory symptoms caused by bacterial infection, particularly accumulation of body fluid such as bronchocavernous plasma exudation, ascites, etc., at the inflammatory site, or excessive increase of blood neutrophils; symptoms resulting from inflammation caused by bacterial infection, particularly accumulation of body fluid such as bronchocavernous plasma exudation ascites, etc., at the inflammatory site, or excessive increase of blood neutrophils, can be alleviated effectively by ingesting or administering orally or parenterally a composition containing human-type lactoferrin as an effective component.

Abstract: A method of producing milk-fermented food, wherein a bifidobacteria or a lactic acid bacteria or a combination of these two bacteria are inoculated into and cultured in a culture medium composed mainly of milk, and an isolated soybean protein or a yeast extract or a combination of these substances are added to the culture medium or a culture obtained by cultivation of the bacteria. The bifidobacteria is one or two species selected from Bifidobacterium breve, Bifidobacterium longum, Bifidobacterium bifidum, or Bifidobacterium infantis.