Patents by Inventor Masami Kagaya

Masami Kagaya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9835619
    Abstract: Acceleration and automation of immunohistochemical staining are achieved as follows: an automatic electric field immunohistochemical staining apparatus is configured to provided with a sample mounting unit, a solution supply unit, an electric field stifling unit, and a washing unit; the sample mounting unit on which a glass substrate with a tissue specimen fixed thereto is mounted and the electric field stirring unit that includes an upper electrode are operated in coordination to activate an antigen in the tissue specimen; the sample mounting unit and the solution supply unit containing various solutions are operated in coordination to supply a primary-antibody-containing solution to the tissue specimen; the sample mounting unit and the electric field stirring unit are operated in coordination to perform an antigen-antibody reaction of the antigen in the tissue specimen and a primary antibody; and the electric field stirring unit and the washing unit are operated in coordination.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: December 5, 2017
    Assignees: Governor of Akita Prefecture, Akita University
    Inventors: Yoichi Akagami, Masami Kagaya, Ryuta Nakamura, Hiroshi Ikeda, Yoshihiro Minamiya, Hiroshi Nanjo
  • Publication number: 20150233902
    Abstract: Acceleration and automation of immunohistochemical staining are achieved as follows: an automatic electric field immunohistochemical staining apparatus is configured to provided with a sample mounting unit, a solution supply unit, an electric field stifling unit, and a washing unit; the sample mounting unit on which a glass substrate with a tissue specimen fixed thereto is mounted and the electric field stirring unit that includes an upper electrode are operated in coordination to activate an antigen in the tissue specimen; the sample mounting unit and the solution supply unit containing various solutions are operated in coordination to supply a primary-antibody-containing solution to the tissue specimen; the sample mounting unit and the electric field stirring unit are operated in coordination to perform an antigen-antibody reaction of the antigen in the tissue specimen and a primary antibody; and the electric field stirring unit and the washing unit are operated in coordination.
    Type: Application
    Filed: February 20, 2014
    Publication date: August 20, 2015
    Applicants: AKITA UNIVERSITY, GOVERNOR OF AKITA PREFECTURE
    Inventors: Yoichi Akagami, Masami Kagaya, Ryuta Nakamura, Hiroshi Ikeda, Yoshihiro Minamiya, Hiroshi Nanjo
  • Patent number: 8283120
    Abstract: A noncontact stirring method, a noncontact stirring apparatus, a method and apparatus for reacting nucleic acid hybridization using the apparatus, a method for detecting nucleic acid in a sample, an apparatus for detecting nucleic acid, a method for detecting antibodies in a sample, and an apparatus for detecting antibodies in minute droplets 1 ?mL or less in an electric field are proposed that can be utilized to speed up biodetection processes, hybridization processes in DNA analysis, ELISA antigen fixing processes, blocking processes, antibody-antigen reaction processes and color reaction processes; and pathogen identification, CRP tests, methods of propagating cells or bacilli such as colon bacilli in a liquid culture medium, and chemical analyses.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: October 9, 2012
    Assignee: Governor of Akita prefecture
    Inventors: Yoichi Akagami, Masami Kagaya
  • Publication number: 20120003669
    Abstract: An immunohistochemical staining apparatus for carrying out immunohistochemical staining includes a sample chamber (1) in which a primary sample (s1) comprised of a tissue specimen (t) to which a primary antibody (Ig1) is applied is disposed between a sample-side electrode (11) and an opposed electrode (12). The sample chamber (1) has first stirring means for noncontactlessly stirring the primary sample (s1) by applying for a first prescribed time period an alternating electric field adjusted so that the opposed electrode (12) is minus with respect to the sample-side electrode (11), and second stirring means for noncontactlessly stirring a secondary sample (s2) comprised of the noncontactlessly-stirred primary sample (s1) to which a labeled secondary antibody (Ig2) is applied by applying for a second prescribed time period an alternating electric field adjusted so that the opposed electrode (12) is minus with respect to the sample-side electrode (11).
    Type: Application
    Filed: June 2, 2011
    Publication date: January 5, 2012
    Inventors: Yoshihiro MINAMIYA, Hiroshi Toda, Jun-ichi Ogawa, Yoichi Akagami, Masami Kagaya
  • Publication number: 20100173300
    Abstract: A noncontact stirring method, a noncontact stirring apparatus, a method and apparatus for reacting nucleic acid hybridization using the apparatus, a method for detecting nucleic acid in a sample, an apparatus for detecting nucleic acid, a method for detecting antibodies in a sample, and an apparatus for detecting antibodies in minute droplets 1 ?mL or less in an electric field are proposed that can be utilized to speed up biodetection processes, hybridization processes in DNA analysis, ELISA antigen fixing processes, blocking processes, antibody-antigen reaction processes and color reaction processes; and pathogen identification, CRP tests, methods of propagating cells or bacilli such as colon bacilli in a liquid culture medium, and chemical analyses.
    Type: Application
    Filed: October 23, 2009
    Publication date: July 8, 2010
    Applicant: Governor of Akita Prefecture
    Inventors: Yoichi AKAGAMI, Masami KAGAYA