Patents by Inventor Masami Kozawa

Masami Kozawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxazolidinone compounds and process for the preparation thereof
    Patent number: 6140506
    Abstract: The present invention produces novel cis-oxazolidinone compound which is racemic form or optically active form, of a formula (1) ##STR1## wherein R represents C.sub.1 -C.sub.6 alkyl group, C.sub.2 -C.sub.6 alkenyl group, C.sub.1 -C.sub.6 alkoxyl group, C.sub.1 -C.sub.6 alkylamino group, aryl group or halogen atom, and oxazolidinone ring is at cis-configuration, comprising reacting cis-1,2-indene epoxide of a formula (3) ##STR2## form, with sulfonyl isocyanate compound of a formula (4) ##STR3## in the presence of metal halide catalyst. Further, cis-1-amino-2-indanol is produced by hydrolyzing the oxazolidinone compound. The latter compound is useful as an intermediate of HIV-drug.
    Type: Grant
    Filed: December 30, 1998
    Date of Patent: October 31, 2000
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Akio Baba, Kenji Suzuki, Yoshinobu Yanagawa, Yoko Ohkuni, Takashi Oda, Masao Shimada, Masami Kozawa