Patents by Inventor Masami Mizu

Masami Mizu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210369597
    Abstract: One aspect of the present invention provides an anti-obesity agent, an anti-dementia agent, a deodorant, an anti-aging agent, an anti-glycation agent, an anti-type I allergy agent, a hypotensive agent, a flavor improving agent, a muscle enhancing agent, and a bone metabolism improving agent which contain a bagasse decomposition extract as an active ingredient.
    Type: Application
    Filed: May 30, 2019
    Publication date: December 2, 2021
    Applicant: Mitsui Sugar Co., Ltd.
    Inventors: Toma Furuta, Masami Mizu, Kiyoaki Miyasaka, Sayoko Fujii, Kazuyo Shiomi, Satoru Itou, Miki Sakazaki
  • Publication number: 20210251884
    Abstract: One aspect of the present invention provides an anti-obesity agent, an anti-dementia agent, a deodorant, an anti-aging agent, an anti-glycation agent, an anti-type I allergy agent, a hypotensive agent, a flavor improving agent, a muscle enhancing agent, and a bone metabolism improving agent which contain a bagasse decomposition extract as an active ingredient.
    Type: Application
    Filed: April 5, 2021
    Publication date: August 19, 2021
    Applicant: Mitsui Sugar Co., Ltd.
    Inventors: Toma Furuta, Masami Mizu, Kiyoaki Miyasaka
  • Publication number: 20210059964
    Abstract: According to an aspect of the present invention, there is provided an anti-I-type allergy agent including: p-coumaric acid as an active ingredient. In addition, according to another aspect of the present invention, there is provided an anti-dementia agent including: p-coumaric acid as an active ingredient.
    Type: Application
    Filed: January 23, 2019
    Publication date: March 4, 2021
    Applicant: Mitsui Sugar Co., Ltd.
    Inventors: Toma Furuta, Masami Mizu
  • Patent number: 9737558
    Abstract: The present invention provides a Peyer's patch activator containing a polysaccharide obtained from sugar cane as an active ingredient, wherein the polysaccharide contains ?-glucan as a main component and has a peak molecular weight within a range of 720,000 to 1,080,000, with a proportion of glucose in all component sugars being 80% or more, and proportions of nonreducing terminal glucose and ?-1,6-linked glucose being 20 to 30% and 15 to 25%, respectively.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: August 22, 2017
    Assignees: Mitsui Sugar Co., Ltd., The Kitasato Institute
    Inventors: Haruki Yamada, Hiroaki Kiyohara, Kazuhiko Otoguro, Aki Ishiyama, Masato Iwatsuki, Satoshi Omura, Masami Mizu, Toshikazu Kawai, Jun Kashimura, Kenji Koge
  • Publication number: 20150258131
    Abstract: The present invention provides a Peyer's patch activator containing a polysaccharide obtained from sugar cane as an active ingredient, wherein the polysaccharide contains ?-glucan as a main component and has a peak molecular weight within a range of 720,000 to 1,080,000, with a proportion of glucose in all component sugars being 80% or more, and proportions of nonreducing terminal glucose and ?-1,6-linked glucose being 20 to 30% and 15 to 25%, respectively.
    Type: Application
    Filed: September 18, 2013
    Publication date: September 17, 2015
    Applicants: The Kitakaso Institute, Mitsui Sugar Co., Ltd.
    Inventors: Haruki Yamada, Hiroaki Kiyohara, Kazuhiko Otoguro, Aki Ishiyama, Masato Iwatsuki, Satoshi Omura, Masami Mizu, Toshikazu Kawai, Jun Kashimura, Kenji Koge
  • Patent number: 7935683
    Abstract: Disclosed is a complex which comprises a carbon nanotube and a modified polysaccharide having a backbone chain with the side thereof being introduced with monosaccharide or oligosaccharide residues. The polysaccharide is preferably ?-1,3-glucan. The complex is prepared by admixing a solution of the modified polysaccharide dissolved in an aprotic polar solvent or a strong alkali solution with an aqueous dispersion of the carbon nanotube, and incubating the mixture.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: May 3, 2011
    Assignees: Japan Science and Technology Agency, Mitsui Sugar Co., Ltd.
    Inventors: Masami Mizu, Seiji Shinkai, Teruaki Hasegawa, Munenori Numata, Tomohisa Fujisawa, Kazuo Sakurai
  • Patent number: 7790189
    Abstract: Disclosed is a new type of immunostimulating agent including an immunostimulating oligonucleotide complexed with a carrier which is safe and has a high transfection effect. The carrier complexed with the immunostimulating oligonucleotide to form the immunostimulating agent is a polysaccharide having ?-1,3-bonds (preferably ?-1,3-glucan such as schizophyllan). A preferred example of the immunostimulating oligonucleotide is one containing an unmethylated CpG motif. The polysaccharide for use is preferably modified with nucleic acid-binding functional group and/or cell membrane-affinitive functional group.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: September 7, 2010
    Assignees: Mitsui Sugar Co., Ltd., Japan Science and Technology Agency
    Inventors: Masami Mizu, Seiji Shinkai, Kazuo Sakurai, Kazuya Koumoto, Munenori Numata, Takahiro Matsumoto
  • Patent number: 7521433
    Abstract: Disclosed are gene carriers utilizing ?-1,3-glucan and methods of preparing the same. The ?-1,3-glucan has at least one 1,6-glucopyranoside branch and is chemically modified through periodate oxidation and reductive amination so as to impart nucleic acid-binding functional groups (for example, cationic functional groups) to at least some of the 1,6-glucopyranoside branches thereof. Triple helix ?-1,3-glucan is dissolved in a polar organic solvent to form single-stranded ?-1,3-glucan. By replacing, in the presence of a nucleic acid, the polar organic solvent for the solution containing the chemically modified single-stranded ?-1,3-glucan by water, a complex (gene carrier) is formed in which the nucleic acid is bound to double-stranded ?-1,3-glucan.
    Type: Grant
    Filed: March 11, 2002
    Date of Patent: April 21, 2009
    Assignees: Japan Science and Technology Agency, Mitsui Sugar Co., Ltd., Fukuoka Prefectural Government
    Inventors: Taro Kimura, Masami Mizu, Kazuo Sakurai, Seiji Shinkai, Kazuya Koumoto
  • Publication number: 20080262210
    Abstract: Disclosed is a new type of immunostimulating agent including an immunostimulating oligonucleotide complexed with a carrier which is safe and has a high transfection effect. The carrier complexed with the immunostimulating oligonucleotide to form the immunostimulating agent is a polysaccharide having ?-1,3-bonds (preferably ?-1,3-glucan such as schizophyllan). A preferred example of the immunostimulating oligonucleotide is one containing an unmethylated CpG motif. The polysaccharide for use is preferably modified with nucleic acid-binding functional group and/or cell membrane-affinitive functional group.
    Type: Application
    Filed: May 13, 2004
    Publication date: October 23, 2008
    Applicants: Mitsui Sugar Co., Ltd., Japan Science and Technology Agency
    Inventors: Masami Mizu, Seiji Shinkai, Kazuo Sakurai, Kazuya Koumoto, Munenori Numata, Takahiro Matsumoto
  • Publication number: 20080242854
    Abstract: Disclosed is a complex which comprises a carbon nanotube and a modified polysaccharide having a backbone chain with the side thereof being introduced with monosaccharide or oligosaccharide residues. The polysaccharide is preferably ?-1,3-glucan. The complex is prepared by admixing a solution of the modified polysaccharide dissolved in an aprotic polar solvent or a strong alkali solution with an aqueous dispersion of the carbon nanotube, and incubating the mixture.
    Type: Application
    Filed: May 16, 2006
    Publication date: October 2, 2008
    Inventors: Masami Mizu, Seiji Shinkai, Teruaki Hasegawa, Munenori Numata, Tomohisa Fujisawa, Kazuo Sakurai
  • Publication number: 20060084149
    Abstract: Disclosed are gene carriers utilizing ?-1,3-glucan and methods of preparing the same. The ?-1,3-glucan has at least one 1,6-glucopyranoside branch and is chemically modified through periodate oxidation and reductive amination so as to impart nucleic acid-binding functional groups (for example, cationic functional groups) to at least some of the 1,6-glucopyranoside branches thereof. Triple helix ?-1,3-glucan is dissolved in a polar organic solvent to form single-stranded ?-1,3-glucan. By replacing, in the presence of a nucleic acid, the polar organic solvent for the solution containing the chemically modified single-stranded ?-1,3-glucan by water, a complex (gene carrier) is formed in which the nucleic acid is bound to double-stranded ?-1,3-glucan.
    Type: Application
    Filed: March 11, 2002
    Publication date: April 20, 2006
    Inventors: Taro Kimura, Masami Mizu, Kazuo Sakurai, Seiji Shinkai, Kazuya Koumoto