Patents by Inventor Masami Sugiyama

Masami Sugiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5171668
    Abstract: A method of chemiluminescence assay of the activity of peroxidase is disclosed, which employes (i) luminol or isoluminol as a substrate, (ii) hydrogen peroxide, and (iii) at lease one compound, serving as an enhancer for the activity of peroxidase, selected from the group consisting of ##STR1## wherein R.sup.1 represents a hydroxyl group, an alkali metal salt of hydroxyl group (--OM, where M is an alkali metal), an amino group which may have a substituent, a halogen, an alkyl group having 1 to 4 carbon atoms, which may have a substituent; R.sup.2 and R.sup.3 each represent hydrogen or a halogen; R.sup.4 and R.sup.5 each represent hydrogen, an alkyl group having 1 to 4 carbon atoms, which may have a substituent, or an alkoxyl group having 1 to 4 carbon atoms, which may have a substituent; ##STR2## wherein R.sup.6 represents an alkyl group having 1 to 6 carbon atoms, which may have a substituent, or an alkene group having 2 to 6 carbon atoms, which may have a substituent, R.sup.7 to R.sup.
    Type: Grant
    Filed: September 29, 1989
    Date of Patent: December 15, 1992
    Assignee: Fujirebio Inc.
    Inventor: Masami Sugiyama
  • Patent number: 4995727
    Abstract: A colorimeter comprises a light source, a mixing box formed of non-coated light diffusing surface manufactured by molding sintering white ceramics or white resin for diffusing and reflecting light from the light source to guide the same to a sample, first light receiving means for receiving light reflected from the sample when light is emitted from the light source, and second light receiving means for receiving light other than the light reflected from the sample emitted from the light source.
    Type: Grant
    Filed: May 19, 1988
    Date of Patent: February 26, 1991
    Assignee: Minolta Camera Kabushiki Kaisha
    Inventors: Nobukazu Kawagoe, Masami Sugiyama, Masahito Inaba
  • Patent number: 4989982
    Abstract: A spectral sensitivity correcting device in a photoelectric tristimulus colorimeter which comprises three light receiving systems for the measurement of tristimulus values. Signals indicative of respective outputs from two of the light receiving systems multiplied by predetermined correction coefficients are added to or subtracted from an output from the remaining light receiving system so that spectral sensitivity characteristics of the remaining light receiving system can approach predetermined spectral sensitivity characteristics.
    Type: Grant
    Filed: August 4, 1989
    Date of Patent: February 5, 1991
    Assignee: Minolta Camera Kabushiki Kaisha
    Inventors: Shigeru Osaki, Masami Sugiyama
  • Patent number: 4909633
    Abstract: A light measuring device wherein a correct measured value can be obtained even if incident light varies in time or a luminance or brightness of an object for measurement is insufficient. The device comprises a branched optical fiber of a random specification having therein three mutually independent light transmission paths for introducing light from a common input end to three output ends. The input end of the optical fiber is located at a slightly defocused position of an objective lens while the output ends are individually opposed to three light receiving elements having different spectral sensitivities. Three components of light are simultaneously converted into electric signals and then into digital values by circuit means each including a double integration analog to digital converter. When a luminance is insufficient at a light receiving element, the gain of the associated analog to digital converter can be adjusted so as to assure appropriate measurement of light.
    Type: Grant
    Filed: May 11, 1987
    Date of Patent: March 20, 1990
    Assignee: Minolta Camera Kabushiki Kaisha
    Inventors: Yoshihiro Okui, Seiiku Ito, Masami Sugiyama
  • Patent number: 4884221
    Abstract: A color measuring apparatus including a photoelectric conversion device for outputting basic color signals corresponding to quantities of light of basic color components of a sample, respectively, a calculating device for calculating a color value of the sample in a predetermined colorimetric system, a target setting device for setting a target color value of the sample in the predetermined colorimetric system, a region setting device for setting a predetermined region containing the target color value, a region decision device for deciding whether or not the color value falls within the predetermined region, an approximation decision device for deciding whether or not the color value has most approximated to the target color value and an output device for outputting a result of the decision of the approximation decision device.
    Type: Grant
    Filed: April 14, 1987
    Date of Patent: November 28, 1989
    Assignee: Minolta Camera Kabushiki Kaisha
    Inventors: Masami Sugiyama, Nobuyuki Kita, Yoshihiro Tasaka
  • Patent number: 4837144
    Abstract: A method of measuring lipid-bound sialic acid (LSA) which comprises, mixing a LSA separating agent comprising a polar solvent with a sample containing LSA and other sialic acid(s), separating the precipitate formed to obtain a supernatant, and measuring the sialic acid concentration of said supernatant by using an enzyme capable of acting on sialic acid in a lipid-bound state. When a sample is treated with the LSA separating agent comprising a polar solvent, various components in the sample such as protein-bound sialic acid and proteinous substances precipitate while the desired lipid-bound sialic acid remains in the supernatent. Accordingly, by measuring sialic acid concentration of the supernatent, LSA concentration of the sample is easily determined. The method of the invention is simple and superior in reproducibility. The method of the invention is suitable for treating a large number of samples, and it can easily by automated. This method is suitable as a screening test for cancer.
    Type: Grant
    Filed: April 20, 1987
    Date of Patent: June 6, 1989
    Assignee: Fujirebio Kabushiki Kaisha, also trading as Fujirebio Inc.
    Inventor: Masami Sugiyama
  • Patent number: 4822998
    Abstract: A spectral sensor comprises that a plurality of arrays of light receiving elements sensitive to different wavelength ranges which are arranged in a non-overlapping relationship with each other within the imaginary circle of a diameter smaller than the sum of lengths of the resective arrays of light receiving elements, and a filtering element of different transmission wavelength for each of the light receiving elements of all of the arrays, which filtering element is arranged in register with the respective light receiving element.
    Type: Grant
    Filed: May 12, 1987
    Date of Patent: April 18, 1989
    Assignee: Minolta Camera Kabushiki Kaisha
    Inventors: Satoshi Yokota, Masami Sugiyama, Nobukazu Kawagoe, Tomoko Miyaura
  • Patent number: 4773761
    Abstract: A photoelectric colorimeter which comprises a photoelectric conversion section including an optical filter to analyze light coming from a test piece and a reference calibrating sample into primary color elements, and a photosensor to convert each of said primary color elements into an electric signal; and a data processing section including a calibration constant calculating device for calculating a calibration constant for each of a plurality of reference calibrating samples on the basis of a calibration point of each of the reference calibrating samples and an information inputted from said photoelectric conversion section, a chromaticity point calculation device for calculating a chromaticity point of the test piece and that of each reference calibrating sample, a memory device for memorizing the calibration constant and calibration point of each of the reference calibrating samples, a device for estimating a new calibration constant suitable for the chromaticity point of the test piece between the respect
    Type: Grant
    Filed: December 16, 1986
    Date of Patent: September 27, 1988
    Assignee: Minolta Camera Kabushiki Kaisha
    Inventors: Masami Sugiyama, Yoshihiro Tasaka
  • Patent number: 4634763
    Abstract: A novel amylase inhibitor, obtained from hard wheat and durum wheat by using dye ligand affinity chromatography having an inhibitory activity on human salivary amylase of less than 0.1 of the inhibitory activity on human pancreatic amylase is disclosed which is useful for measuring isoenzymes of amylase in the field of clinical tests.
    Type: Grant
    Filed: September 30, 1982
    Date of Patent: January 6, 1987
    Assignee: Fujizoki Pharmaceutical Co., Ltd.
    Inventors: Masami Sugiyama, Yasushi Kasahara
  • Patent number: 4551272
    Abstract: Derivatives of dipeptide having the following general formula and their use as substrates for colorimetrically or spectrophotometrically measuring the activity of carboxypeptidase A: ##STR1## wherein X is OH in ortho or para position, or NH.sub.2 or CH.sub.
    Type: Grant
    Filed: January 6, 1984
    Date of Patent: November 5, 1985
    Assignee: Fujirebio Kabushiki Kaisha
    Inventors: Masami Sugiyama, Hiroko Shibuya, Yasushi Kasahara
  • Patent number: 4432896
    Abstract: Derivatives of hippuryl-L-phenylalanine having the following general formula: ##STR1## wherein X represents OH or CH.sub.3 O useful as substrates for measuring the actively of carboxy peptidose A.
    Type: Grant
    Filed: September 24, 1982
    Date of Patent: February 21, 1984
    Assignee: Fujirebio Kabushiki Kaisha
    Inventors: Masami Sugiyama, Yasushi Kasahara, Yoshihiro Ashihara
  • Patent number: 4419445
    Abstract: A method for determining the activity of cholinesterase comprising the steps of:mixing a solution containing p-methoxybenzoate demethylmonooxygenase, nicotinamide adenine dinucleotide reduced form (NADH) and p-methoxybenzoyl choline cation having the following formula: ##STR1## with a liquid containing cholinesterase, measuring the decrease in absorbance of light by NADH, which is based on a consumption of NADH, and calculating the activity of cholinesterase therefrom.
    Type: Grant
    Filed: March 22, 1982
    Date of Patent: December 6, 1983
    Assignee: Fujizoki Pharmaceutical Co., Ltd.
    Inventors: Yasushi Kasahara, Yoshihiro Ashihara, Masami Sugiyama, Takahiro Harada
  • Patent number: 4205918
    Abstract: A hand-carriable, compact color meter for indicating proper amount of adjustment of color compensation filters interposed in the light path of a color printer for the compensation of color balance of the light illuminating a film or the slide set on the printer. The color meter includes an indicating lamp, a photocell to be exposed to the light passing through the film or slide, a plurality of optical color filters selectively disposed in front of the photocell to provide the photocell with spectral sensitivities corresponding to the spectral sensitivity of the printing paper, a plurality of fixed or variable resistors selectable in correspondence to the selection of the color filter, and an electric circuit for actuating the indicating lamp in accordance with the relationship between the output of the light measuring circuit and a reference voltage commensurate with the selected one of the resistors.
    Type: Grant
    Filed: February 27, 1978
    Date of Patent: June 3, 1980
    Assignee: Minolta Camera Kabushiki Kaisha
    Inventors: Tohru Kisanuki, Masami Sugiyama, Takeshi Kosaka