Patents by Inventor Masami UKAWA

Masami UKAWA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYMER COMPOUND AND PROMOTER FOR INTRODUCING COMPOUND INTO CELLS USING SAME
    Publication number: 20210268113
    Abstract: The object of the present invention is to provide a technique for promoting membrane permeation of a drug, which is highly versatile and highly safe. The object can be solved by a polymer compound having a molecular weight of 1000 or more, wherein the polymer compound has, at an end of a side chain, one arginine or a basic peptide of chain length of 2 to 6 containing one or more arginine, and comprises a guanidino group of 0.5 to 20 mmol/g, originating from arginine.
    Type: Application
    Filed: July 11, 2019
    Publication date: September 2, 2021
    Applicants: JOSHO GAKUEN EDUCATIONAL FOUNDATION, ADEKA CORPORATION
    Inventors: Shinji SAKUMA, Masami UKAWA, Shunsuke TAKAHI, Kazunori FUKUSHIMA, Mio MUTO, Kohei MIYATA, Akiko TASAKI, Hotaru MATSUMOTO
  • Cationic lipid having improved intracellular kinetics
    Patent number: 9708628
    Abstract: The present invention relates to a compound represented by the formula (1) wherein Xa and Xb are each independently X1 or X2; s is 1 or 2, R4 is an alkyl group having 1-6 carbon atoms, na and nb are each independently 0 or 1, R1a and R1b are each independently an alkylene group having 1-6 carbon atoms, R2a and R2b are each independently an alkylene group having 1-6 carbon atoms, Ya and Yb are each independently an ester bond, an amide bond, a carbamate bond, an ether bond or a urea bond, and R3a and R3b are each independently a sterol residue, a liposoluble vitamin residue or an aliphatic hydrocarbon group having 12-22 carbon atoms, and use thereof.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: July 18, 2017
    Assignees: NOF Corporation, National University Corporation Hokkaido University
    Inventors: Kota Tange, Masaya Arai, Kazuhiro Kubo, Hidetaka Akita, Hideyoshi Harashima, Hiroto Hatakeyama, Ryohei Ishiba, Masami Ukawa, Hiroki Tanaka
  • CATIONIC LIPID HAVING IMPROVED INTRACELLULAR KINETICS
    Publication number: 20140335157
    Abstract: The present invention relates to a compound represented by the formula (1) wherein Xa and Xb are each independently X1 or X2; s is 1 or 2, R4 is an alkyl group having 1-6 carbon atoms, na and nb are each independently 0 or 1, R1a and R1b are each independently an alkylene group having 1-6 carbon atoms, R2a and R2b are each independently an alkylene group having 1-6 carbon atoms, Ya and Yb are each independently an ester bond, an amide bond, a carbamate bond, an ether bond or a urea bond, and R3a and R3b are each independently a sterol residue, a liposoluble vitamin residue or an aliphatic hydrocarbon group having 12-22 carbon atoms, and use thereof.
    Type: Application
    Filed: May 16, 2014
    Publication date: November 13, 2014
    Inventors: Kota TANGE, Masaya ARAI, Kazuhiro KUBO, Hidetaka AKITA, Hideyoshi HARASHIMA, Hiroto HATAKEYAMA, Ryohei ISHIBA, Masami UKAWA, Hiroki TANAKA