Patents by Inventor Masamichi Muramatsu

Masamichi Muramatsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cytidine deaminase
    Patent number: 7314621
    Abstract: Antibodies that specifically bind to AID (Activation-Induced cytidine Deaminase) proteins, compositions comprising said antibodies, and cells producing said antibodies, are described. The AID proteins are structurally related to APOBEC-1,l an RNA editing enzyme, and have a cytidine deaminase activity similar to APOBEC-1. The AID genes were found by preparing cDNA libraries from mouse B cell clone CH12F3-2 (which undergoes class switch recombination from IgM to IgA at an extremely high rate after activation of the cells by stimulation with cytokines), with and without stimulation with cytokines, and performing subtraction cloning using the libraries.
    Type: Grant
    Filed: July 11, 2006
    Date of Patent: January 1, 2008
    Assignee: Kyoto University
    Inventors: Tasuku Honjo, Masamichi Muramatsu
  • Cytidine deaminase
    Publication number: 20060246568
    Abstract: Genes encoding novel proteins named AID (Activation-Induced cytidine Deaminase) are described. The AID proteins are structurally related to APOBEC-1, an RNA editing enzyme, and have a cytidine deaminase activity similar to APOBEC-1. The AID genes were found by preparing cDNA libraries from mouse B cell clone CH12F3-2 (which undergoes class switch recombination from IgM to IgA at an extremely high rate after activation of the cells by stimulation with cytokines), with and without stimulation with cytokines, and performing subtraction cloning using the libraries.
    Type: Application
    Filed: July 11, 2006
    Publication date: November 2, 2006
    Inventors: Tasuku Honjo, Masamichi Muramatsu
  • Cytidine deaminase
    Patent number: 7083966
    Abstract: Genes encoding novel proteins named AID (Activation-Induced cytidine Deaminase) are described. The AID proteins are structurally related to APOBEC-1, an RNA editing enzyme, and have a cytidine deaminase activity similar to APOBEC-1. The AID genes were found by preparing cDNA libraries from mouse B cell clone CH12F3-2 (which undergoes class switch recombination from IgM to IgA at an extremely high rate after activation of the cells by stimulation with cytokines), with and without stimulation with cytokines, and performing subtraction cloning using the libranes.
    Type: Grant
    Filed: July 2, 2004
    Date of Patent: August 1, 2006
    Assignee: Kyoto University
    Inventors: Tasuku Honjo, Masamichi Muramatsu
  • Cytidine deaminase
    Publication number: 20050054073
    Abstract: Genes encoding novel proteins named AID (Activation-Induced cytidine Deaminase), that are structurally related to APOBEC-1, an RNA editing enzyme, and have a cytidine deaminase activity similar to APOBEC-1, have been found by preparing cDNA libraries from mouse B cell clone CH12F3-2 (which undergoes class switch recombination from IgM to IgA at an extremely high rate after activation of the cells by stimulation with cytokines), with and without stimulation with cytokines, and performing subtraction cloning using the libraries.
    Type: Application
    Filed: July 2, 2004
    Publication date: March 10, 2005
    Inventors: Tasuku Honjo, Masamichi Muramatsu
  • Cytidine deaminase
    Patent number: 6815194
    Abstract: Genes encoding novel proteins named AID (Activation-Induced cytidine Deaminase), that are structurally related to APOBEC-1, an RNA editing enzyme, and have a cytidine deaminase activity similar to APOBEC-1, have been found by preparing cDNA libraries from mouse B cell clone CH12F3-2 (which undergoes class switch recombination from IgM to IgA at an extremely high rate after activation of the cells by stimulation with cytokines), with and without stimulation with cytokines, and performing subtraction cloning using the libraries.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: November 9, 2004
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Tasuku Honjo, Masamichi Muramatsu
  • Novel cytidine deaminase
    Publication number: 20020164743
    Abstract: Genes encoding novel proteins named AID (Activation-Induced cytidine Deaminase), having structural relationship to APOBEC-1, one of RNA editing enzymes, and having a cytidine deaminase activity similar to APOBEC-1, has been found by preparing cDNA libraries for mouse B cell clone CH12F3-2, which undergoes class switch recombination from IgM to IgA at an extremely high rate together with activation of cells by stimulation with cytokines, with and without stimulating with cytokine, and performing subtraction cloning using the libraries.
    Type: Application
    Filed: September 28, 2001
    Publication date: November 7, 2002
    Inventors: Tasuku Honjo, Masamichi Muramatsu