Patents by Inventor Masamichi Satoh

Masamichi Satoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radiolabeled 3-[3-(benzoyl-amido)benzyloxy]aspartic acid derivative and method of producing the same
    Patent number: 8097654
    Abstract: The present invention provides a radiolabeled ligand which is highly selective and potent for glutamate transporters and is usable in specifically detecting the glutamate transporter. Specifically, the present invention provides a 3-[3-(benzoylamido)benzyloxy]aspartic acid having a radioactive substituent on the benzoyl group which is represented by the following formula (1), or an ester or salt thereof: wherein X represents a substituent containing a radioactive atom(s) which is selected from a straight or branched lower aliphatic alkyl group, a hydroxyl group, a straight or branched lower aliphatic alkoxy group, an amino group, a straight or branched lower aliphatic acylamido group, a halogen atom and a straight or branched lower aliphatic haloalkyl group; and R1 and R2 each represents a hydrogen atom, a straight or branched lower aliphatic alkyl group or an acetoxymethyl group.
    Type: Grant
    Filed: March 18, 2005
    Date of Patent: January 17, 2012
    Assignee: Suntory Holdings Limited
    Inventors: Keiko Shimamoto, Hideo Saji, Yuji Kuge, Masashi Ueda, Masamichi Satoh, Takayuki Nakagawa
  • Radiolabeled 3-[3- (Benzoyl-Amido) Benzyloxy] Aspartic Acid Derivative and Method of Producing the Same
    Publication number: 20080248485
    Abstract: The present invention provides a radiolabeled ligand which is highly selective and potent for glutamate transporters and is usable in specifically detecting the glutamate transporter. Specifically, the present invention provides a 3-[3-(benzoylamido)benzyloxy]aspartic acid having a radioactive substituent on the benzoyl group which is represented by the following formula (1), or an ester or salt thereof: wherein X represents a substituent containing a radioactive atom(s) which is selected from a straight or branched lower aliphatic alkyl group, a hydroxyl group, a straight or branched lower aliphatic alkoxy group, an amino group, a straight or branched lower aliphatic acylamido group, a halogen atom and a straight or branched lower aliphatic haloalkyl group; and R1 and R2 each represents a hydrogen atom, a straight or branched lower aliphatic alkyl group or an acetoxymethyl group.
    Type: Application
    Filed: March 18, 2005
    Publication date: October 9, 2008
    Inventors: Keiko Shimamoto, Hideo Saji, Yuji Kuge, Masashi Ueda, Masamichi Satoh, Takayuki Nakagawa
  • Agent for expression of long-term potentiation of synaptic transmission comprising compound having brain somatostatin activation property
    Patent number: 6613572
    Abstract: The present invention relates to an agent for the expression of long-term potentiation of synaptic transmission, which contains a compound having a brain somatostatin activation property as an active ingredient and to a screening method of an agent for the expression of long-term potentiation of synaptic transmission, which uses a somatostatin releasing property as an index. The present invention is useful for the prophylaxis and/or treatment of cerebral diseases of dementia, amnesia, manic-depressive psychosis, schizophrenia, Parkinson's disease, psychosomatic disease and the like.
    Type: Grant
    Filed: January 10, 2002
    Date of Patent: September 2, 2003
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Nobuya Matsuoka, Masamichi Satoh
  • Agent for expression of long-term potentiation of synaptic transmission comprising compound having brain somatostatin activation property
    Publication number: 20020090732
    Abstract: The present invention relates to an agent for the expression of long-term potentiation of synaptic transmission, which contains a compound having a brain somatostatin activation property as an active ingredient and to a screening method of an agent for the expression of long-term potentiation of synaptic transmission, which uses a somatostatin releasing property as an index The present invention is useful for the prophylaxis and/or treatment of cerebral diseases of dementia, amnesia, manic-depressive psychosis, schizophrenia, Parkinson's disease, psychosomatic disease and the like.
    Type: Application
    Filed: January 10, 2002
    Publication date: July 11, 2002
    Applicant: Fujisawa Pharmaceutical Co. Ltd.
    Inventors: Nobuya Matsuoka, Masamichi Satoh
  • Agent for expression of long-term potentiation of synaptic transmission comprising compound having brain somatostatin activation property
    Patent number: 6344358
    Abstract: The present invention relates to an agent for the expression of long-term potentiation of synaptic transmission, which contains a compound having a brain somatostatin activation property as an active ingredient and to a screening method of an agent for the expression of long-term potentiation of synaptic transmission, which uses a soniatostatin releasing property as an index. The present invention is useful for the prophylaxis and/or treatment of cerebral diseases of dementia, amnesia, manic-depressive psychosis, schizophrenia, Parkinson's disease, psychosomatic disease and the like.
    Type: Grant
    Filed: May 28, 1999
    Date of Patent: February 5, 2002
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Nobuya Matsuoka, Masamichi Satoh