Patents by Inventor Masamichi Sugimoto

Masamichi Sugimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREVENTIVE OR THERAPEUTIC AGENT FOR PSORIASIS COMPRISING IL-6 ANTAGONIST AS ACTIVE INGREDIENT
    Publication number: 20080124325
    Abstract: A method for treating psoriasis comprising an interleukin-6 (IL-6) antagonist such as, for example, an antibody against IL-6 receptor.
    Type: Application
    Filed: November 29, 2007
    Publication date: May 29, 2008
    Inventors: Hiroaki Ito, Kazuyuki Yoshizaki, Norihiro Nishimoto, Tadamitsu Kishimoto, Shin Shimaoka, Hidetomo Kitamura, Masamichi Sugimoto, Kenichi Akamatsu
  • Preventives or remedies for psoriasis containing as the active ingredient IL-6 antagonist
    Patent number: 7320792
    Abstract: A preventive and therapeutic agent for psoriasis comprising an interleukin-6 (IL-6) antagonist such as, for example, an antibody against IL-6 receptor.
    Type: Grant
    Filed: October 25, 2001
    Date of Patent: January 22, 2008
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hiroaki Ito, Kazuyuki Yoshizaki, Norihiro Nishimoto, Tadamitsu Kishimoto, Shin Shimaoka, Hidetomo Kitamura, Masamichi Sugimoto, Kenichi Akamatsu
  • Adjuvant Therapy with the Use of Anti-Glypican 3 Antibody
    Publication number: 20070269444
    Abstract: The present invention provides an anti-cancer agent comprising anti-glypican 3 antibody wherein the anti-cancer agent is administered after a cancer treatment, Preferably, after a cancer treatment is after a treatment for liver cancer, and the treatment for liver cancer is in particular a resection of liver cancer cells. The anti-cancer agent according to the present invention is preferably administered if glypican 3 is expressed in the resected liver cancer cells. The anti-glypican 3 antibody is preferably a monoclonal antibody. The anti-cancer agent according to the present invention is useful for preventing cancer and for preventing the recurrence of cancer.
    Type: Application
    Filed: August 23, 2005
    Publication date: November 22, 2007
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Yasuko Kinoshita, Masamichi Sugimoto, Hisafumi Okabe
  • Sugar-chain-altered anti-hm1.24 antibody
    Publication number: 20070142627
    Abstract: An antibody (anti-HM1.24 antibody) against HM1.24 antigen in which the alteration of sugar chains resulted in enhanced antibody-dependent cellular cytotoxicity (ADCC), specifically an antibody having a sugar chain that does not contain ?-1,6 core fucose, an antibody having a sugar chain that contains a bisecting N-acetylglucosamine (GlcNAc) structure, or an antibody having a sugar chain that does not contain ?-1,6 core fucose and having a sugar chain that contains a bisecting N-acetylglucosamine (GlcNAc) structure.
    Type: Application
    Filed: August 11, 2004
    Publication date: June 21, 2007
    Inventors: Masayuki Tsuchiya, Shigeyuki Iijima, Izumi Sugo, Masamichi Sugimoto
  • Anti-glypican-3 antibody
    Publication number: 20070087005
    Abstract: An anti-glypican-3 antibody comprising one or more amino acid substitutions introduced in the Fc region is disclosed. Preferably, in the anti-glypican-3 antibody, one or more of the amino acid residues at the positions 239, 298, 326, 330 and 332 in the Fc region are substituted with other amino acid residues. Since the Fc-modified anti-glypican-3 antibody of the invention exhibit enhanced ADCC activity, it is useful in treating cancers, such as hepatic cancer. Also disclosed are an anticancer agent comprising the anti-glypican-3 antibody of the invention and a pharmaceutically acceptable carrier, as well as a method of treating a patient with cancer comprising administering to the patient the anticancer agent of the invention.
    Type: Application
    Filed: October 14, 2005
    Publication date: April 19, 2007
    Inventors: Gregory Lazar, Bassil Dahiyat, Hisafumi Okabe, Masamichi Sugimoto, Shigeyuki Iijima, Izumi Sugo
  • Preventives or remedies for psoriasis containing as the active ingredient il-6 antagonist
    Publication number: 20040028681
    Abstract: A preventive and therapeutic agent for psoriasis comprising an interleukin-6 (IL-6) antagonist such as, for example, an antibody against IL-6 receptor.
    Type: Application
    Filed: April 24, 2003
    Publication date: February 12, 2004
    Inventors: Hiroaki Ito, Kazuyuki Yoshizaki, Norihiro Nishimoto, Tadamitsu Kishimoto, Shin Shimaoka, Hidetomo Kitamura, Masamichi Sugimoto, Kenichi Akamatsu