Abstract: The present invention relates to carboxylic acid esters of the formula (I), ##STR1## wherein R.sub.1 is a hydrogen atom or a methyl group, and when R.sub.1 is a hydrogen atom, R.sub.2 is a group of the formula, ##STR2## (in which X is a methyl group, a chlorine, bromine or fluorine atom), and when R.sub.1 is a methyl group, R.sub.2 is a methyl group; and Y is a 1-methyl-2-propenyl, 1-methyl-2-propynyl, 2-cyclopentenyl or 2-cyclohexenyl group, and their production and use as an insecticide.

Abstract: The present invention relates to a novel process for producing pyrimidine nucleosides by a reaction between bis(tri-lower alkylstannyl)-5-halogenouracil and 2-substituted tetrahydrofurane. The novel process of the present invention makes it possible to obtain, depending upon the manner of substitution of tetrahydrofurane residue on two nitrogen atoms N.sub.1 and N.sub.3 of 5-halogenouracil, N.sub.1 -mono-substituted compound, N.sub.3 -mono-substituted compound and N.sub.1,N-di-substituted compound among which the last can be converted by hydrolysis thereof into N.sub.1 -mono-substituted compound. The present invention further relates to novel N.sub.3 -mono-substituted compounds and N.sub.1,N.sub.3 -di-substituted compounds obtained by such process. The present invention still further relates to novel bis-(tri-lower alkylstannyl)-5-halogenouracil used in the present invention as a raw compound.

Abstract: The present invention relates to a novel process for producing pyrimidine nucleosides by a reaction between bis(tri-lower alkylstannyl)-5-halogenouracil and 2-substituted tetrahydrofurane. The novel process of the present invention makes it possible to obtain, depending upon the manner of substitution of tetrahydrofurane residue on two nitrogen atoms N.sub.1 and N.sub.3 of 5-halogenouracil, N.sub.1 -mono-substituted compound, N.sub.3 -mono-substituted compound and N.sub.1,N-di-substituted compound among which the last can be converted by hydrolysis thereof into N.sub.1 -mono-substituted compound. The present invention further relates to novel N.sub.3 -mono-substituted compounds and N.sub.1,N.sub.3 -di-substituted compounds obtained by such process. The present invention still further relates to novel bis-(tri-lower alkylstannyl)-5-halogenouracil used in the present invention as a raw compound.

Abstract: Ureylenethiophanes and their related compounds of the formula: ##SPC1##Having a cis-configuration on the ureylene or thioureylene juncture, which are useful as the intermediates in the synthesis of biologically active biotin and its related compounds, can be produced selectively by reacting the corresponding compounds of the formula: ##SPC2##With isocyanates or isothiocyanates wherein R is a hydrogen atom, an alkyl group or an aralkyl group, R.sub.1 and R.sub.2 are each a hydrogen atom or an aliphatic hydrocarbon group bearing or not a carboxyl group or any other group convertible thereto at the terminal position, X is a halogen atom, Y is an oxygen atom or a sulfur atom and Z is an oxygen atom, a sulfur atom, a sulfinyl group or a sulfonyl group.

Abstract: A process for producing cyclopentane derivatives of the formula ##SPC1##Wherein R is hydrogen or a C.sub.1 to C.sub.6 alkyl group, X is a carboxyl or a carboalkoxy group, and the like; Y and Z each is a hydroxyl group, and the like; and n is an integer of from 5 to 7. The derivatives are useful as medicines. The process of this invention comprises the steps shown in the following reaction scheme: ##SPC2##Wherein R, X, Y, Z and n are as defined above, and wherein R' is lower alkyl group.

Abstract: The present invention relates to a process for preparing allethrolone which involves hydrolyzing 2-allyl-4-hydroxy-3-methyl-2-cyclopentenone acid phthalate represented by the formula ##SPC1##In water or an aqueous solvent with or without a base of less than a small excess of the equivalent.

Abstract: Cyclopentane derivatives of the formula ##SPC1##Wherein R.sup.1 is a group of the formula--(CH.sub.2).sub.n --Xin which X is a carboxyl group or its homologue, a halogen atom or a hydroxyl group and n is an integer of from 1 to 7; Y.sup.1 is a formyl group of a carboxyl group or its homologue; and Z.sup.1 is a formyl group, a carboxyl group, a hydroxymethyl group, an acetyl group, an acetoxy group, or a hydroxyl group and a process for their preparation are disclosed. The process schematically comprises the Diels-Alder reaction of a compound having the formula R.sup.1 --CH=CH--Y.sup.1 with cyclopentadiene followed by oxidation of the bicycloheptene reaction product formed into a cyclopentane derivative in which Z.sup.1 is a formyl group, a hydroxymethyl group or a carboxy group.

Abstract: Polyene compounds of the formula: ##EQU1## wherein R' is protected or unprotected hydroxyl or a group of the formula: ##EQU2## (in which R" and R"' are each carboxyl or a group convertible into carboxyl on hydrolysis), m is a positive integer and n is 0 or a positive integer, which are useful as intermediates in the synthesis of coenzyme Q, can be produced advantageously through a step for the dehydration of a compound of the formula: ##EQU3## wherein R', m and n are each as defined above.