Abstract: Disclosed are a curcumin derivative or a salt thereof, which contains a fluorine atom, represented by formula (I): (wherein R1a and R1b are each independently a hydrogen atom, alkyl, acetyl, or methoxycarbonyl; R2s are each independently a fluorine atom, CHF2—, CF3—, CHF2O—, or CF3O—; R3s are each independently a hydrogen atom or a fluorine atom; A is alkyl, cyano, carboxyl, alkoxycarbonyl, or R4—(CH2)m—; R4 is hydroxy, carboxy, cyano, acetyloxy, alkoxycarbonyl, alkoxyalkoxy, hydroxyalkoxy, or CONR5R6; R5 and R6 are each independently a hydrogen atom or alkyl; and m is an integer from 1 to 5), and a diagnostic imaging agent for diagnosing a disease in which an amyloid ? peptide aggregate accumulates, the diagnostic imaging agent containing a compound having a 1,3-dicarbonyl structure, wherein the compound exists in a keto form and an enol form, and the keto form and the enol form have different affinities, respectively, to the amyloid ? peptide aggregate.

Abstract: Provided is a gear device capable of resolving inconveniences such as abnormal wear that arises due to the relative misalignment between the internal gear pins and the external gear, and inhibiting an increase in the number of components. This gear device has an outer cylinder, internal gear pins, and a carrier. A plurality of pin grooves extending in the axial direction of the outer cylinder are formed on the inner peripheral face of the outer cylinder, and the internal gear pins are fitted in the pin grooves. The pin grooves are formed so that the length of the pin grooves becomes longer than the length of the internal gear pins. The carrier has a pair of pressing members which includes a pressing surface. The pressing surface is configured to regulate movement of the internal gear pins and an oscillating gear which includes external teeth in the axial direction.

Abstract: Provided is a gear device capable of resolving inconveniences such as abnormal wear that arises due to the relative misalignment between the internal gear pins and the external gear, and inhibiting an increase in the number of components. This gear device has an outer cylinder, internal gear pins, and a carrier. A plurality of pin grooves extending in the axial direction of the outer cylinder are formed on the inner peripheral face of the outer cylinder, and the internal gear pins are fitted in the pin grooves. The pin grooves are formed so that the length of the pin grooves becomes longer than the length of the internal gear pins. The carrier has a pair of pressing members which includes a pressing surface. The pressing surface is configured to regulate movement of the internal gear pins and an oscillating gear which includes external teeth in the axial direction.

Abstract: An information processing apparatus includes a connector that conforms to a Universal Serial Bus standard. The information processing apparatus detects voltages at signal terminals of the connector a plurality of times, and judges a type of an apparatus connected to the connector by using detection results obtained the plurality of times.

Abstract: Disclosed are a curcumin derivative or a salt thereof, which contains a fluorine atom, represented by formula (I): (wherein R1a and R1b are each independently a hydrogen atom, alkyl, acetyl, or methoxycarbonyl; R2s are each independently a fluorine atom, CHF2—, CF3—, CHF2O—, or CF3O—; R3s are each independently a hydrogen atom or a fluorine atom; A is alkyl, cyano, carboxyl, alkoxycarbonyl, or R4—(CH2)m—; R4 is hydroxy, carboxy, cyano, acetyloxy, alkoxycarbonyl, alkoxyalkoxy, hydroxyalkoxy, or CONR5R6; R5 and R6 are each independently a hydrogen atom or alkyl; and m is an integer from 1 to 5), and a diagnostic imaging agent for diagnosing a disease in which an amyloid ? peptide aggregate accumulates, the diagnostic imaging agent containing a compound having a 1,3-dicarbonyl structure, wherein the compound exists in a keto form and an enol form, and the keto form and the enol form have different affinities, respectively, to the amyloid ? peptide aggregate.

Abstract: An information processing apparatus includes a connector that conforms to a Universal Serial Bus standard. The information processing apparatus detects voltages at signal terminals of the connector a plurality of times, and judges a type of an apparatus connected to the connector by using detection results obtained the plurality of times.

Abstract: A polypeptide which is a tumor necrosis factor polypeptide having an amino acid sequence represented by from the 1st Ser to the 155th Leu as shown by SEQ ID NO:1 in the Sequence Listing, or its mutein, wherein the amino acid sequence of the 1st Ser to the 8th Asp of the SEQ ID NO:1 or the corresponding amino acid sequence of the mutein is replaced by an amino acid sequence containing at least one amino acid sequence of Arg-Gly-Asp and from 3 to 16 amino acids. Also disclosed are a recombinant plasmid containing a DNA encoding such a polypeptide, a recombinant microbial cell transformed by such a recombinant plasmid, a process for producing the polypeptide, a pharmaceutical composition comprising the polypeptide as an active ingredient, and a DNA for the polypeptide.

Abstract: A polypeptide which is a tumor necrosis factor polypeptide having an amino acid sequence represented by from the 1st Ser to the 155th Leu as shown by SEQ ID NO:1 in the Sequence Listing, or its mutein, wherein the amino acid sequence of the 1st Ser to the 8th Asp of the SEQ ID NO:1 or the corresponding amino acid sequence of the mutein is replaced by an amino acid sequence containing at least one amino acid sequence of cell-adherent peptide of laminin and from 5 to 30 amino acids. Also disclosed are a recombinant plasmid containing a DNA encoding such a polypeptide, a recombinant microbial cell transformed by such a recombinant plasmid, a process for producing the polypeptide, a pharmaceutical composition comprising the polypeptide as an active ingredient, and a DNA for the polypeptide.