Patents by Inventor Masanobu Kawamata

Masanobu Kawamata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4769183
    Abstract: Sodium 1,4-dimethylisopropylazulene-3-sulfonate is stabilized by dissolving it in a suitable solvent and thereafter removing the solvent from the solution by spray-drying or lyophilization.
    Type: Grant
    Filed: March 9, 1983
    Date of Patent: September 6, 1988
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Masanobu Kawamata, Koichi Ushimaru, Hiroyuki Goshi, Hideichi Miyasako
  • Patent number: 4751217
    Abstract: A compound of the formula (I): ##STR1## in which: is a single bond or a double bond,X is hydrogen or hydroxy,n is 0 or 1,Z is ##STR2## when in ring B is a double bond, and, when in ring B is a single bond, Z is wherein W is hydrogen, lower acyl, unsubstituted arylcarbonyl, lower alkyl or substituted arylcarbonyl.These compounds are useful as platelet aggregation inhibitors.
    Type: Grant
    Filed: October 22, 1985
    Date of Patent: June 14, 1988
    Assignees: Nippon Shinyaku Co., Ltd., Takara Shuzo Co., Ltd.
    Inventors: Masanobu Kawamata, Yoji Ezure, Nobutoshi Ojima, Kiyotaka Konno, Teruya Nakamura, Hideyuki Yasuda
  • Patent number: 4657907
    Abstract: 2,4-diamino-6-(2,5-dichlorophenyl)-1,3,5-triazine and pharmaceutically acceptable acid addition salts thereof in finely pulverized form so that the average particle diameter is 20 microns or less have been found to be particularly useful for the treatment of peptic ulcers. When administered to humans in need thereof, 1 to 4 mg per day has been found effective.
    Type: Grant
    Filed: April 12, 1985
    Date of Patent: April 14, 1987
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Hiroshi Enomoto, Masanobu Kawamata, Akira Nomura, Yoshiaki Aoyagi, Fusao Ueda
  • Patent number: 4614796
    Abstract: Liposomes of steryl glucosides and/or steryl glucoside monopalmitates are useful for hemostatic, vascular stabilization and anti-shock effects, particularly in the form of injectable solutions.
    Type: Grant
    Filed: March 25, 1983
    Date of Patent: September 30, 1986
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Masanobu Kawamata, Koichi Ushimaru, Shuji Yamane
  • Patent number: 4533552
    Abstract: Sodium 1,4-dimethylisopropylazulene-3-sulfonate is stabilized by adding to a solution thereof, physiologically non-toxic additives and then removing or separating the solvent therefrom by spray drying or a lyophilization.
    Type: Grant
    Filed: May 11, 1983
    Date of Patent: August 6, 1985
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Masanobu Kawamata, Koichi Ushimaru, Hiroyuki Goshi, Hideichi Miyasako
  • Patent number: 4532238
    Abstract: 2,4-Diamino-6-(2,5-dichlorophenyl)-1,3,5-triazine and pharmaceutically acceptable acid addition salts thereof in finely pulverized form so that the average particle diameter is 20 microns or less have been found to be particularly useful for the treatment of peptic ulcers.
    Type: Grant
    Filed: July 30, 1982
    Date of Patent: July 30, 1985
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Hiroshi Enomoto, Masanobu Kawamata, Akira Nomura, Yoshiaki Aoyagi, Fusao Ueda
  • Patent number: 4129649
    Abstract: A process for producing amorphous preparations of steryl glucoside monopalmitates, wherein steryl glucoside monopalmitates are heated at a temperature above 110.degree. C up to about 145.degree. C or the compounds are dissolved in an organic solvent in which they are soluble with a solvent which is then distilled off, and the compounds then pulverized and mixed with physiologically harmless organic or inorganic fine particles in a proportion of 0.5 times (by weight) of the compounds or more, thereby homogeneously dispersing the amorphous compounds in the fine particles or uniformtly adsorbing the compounds on the fine particles, and the resulting preparations which have hemostatic properties and are readily absorbable upon ingestion. The starting steryl glucoside monopalmitates are obtained in crystalline form as from soy beans or other vegetable sources.
    Type: Grant
    Filed: May 5, 1976
    Date of Patent: December 12, 1978
    Assignee: Nippon Shinyaku Co. Ltd.
    Inventors: Sho Inoue, Masanobu Kawamata, Hirokazu Ushimaru, Koichi Nakamichi, Yutaka Takahashi
  • Patent number: 4083969
    Abstract: Sterol glycosides are rendered easily absorbable through the digestive tract by dissolving or dispersing the steroid glycoside with heating into a water solution of a polymer or polymers and then removing the solvent.
    Type: Grant
    Filed: April 7, 1976
    Date of Patent: April 11, 1978
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Sho Inoue, Masanobu Kawamata, Hirokazu Ushimaru, Koichi Nakamichi, Yutaka Takahashi
  • Patent number: 3966918
    Abstract: A method of preparing aqueous solutions of sterol glycosides and their ester derivatives characterized by solubilizing sterol glycosides and their ester derivatives by (1) dissolving said sterol glycoside or ester in a lower aliphatic alcohol and subsequently adding a hydrophilic non-ionic surface active agent, or (2) mixing or dissolving said sterol glycoside or ester with or in a lipophilic surface active agent or its solution in an organic solvent miscible with water and subsequently adding a hydrophilic surface active agent.
    Type: Grant
    Filed: November 22, 1974
    Date of Patent: June 29, 1976
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Masanobu Kawamata, Hirokazu Ushimaru, Akira Sano, Yutaka Takahashi