Patents by Inventor Masanobu Komatsu

Masanobu Komatsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11922307
    Abstract: With respect to an inference method performed by at least one processor, the method includes inputting, by the at least one processor, into a learned model, non-processed object image data of a second object and data related to a second process for the second object, and inferring, by the at least one processor using the learned model, processed object image data of the second object on which the second process has been performed. The learned model has been trained so that an output obtained in response to non-processed object image data of a first object and data related to a first process for the first object being input approaches processed object image data of the first object on which the first process has been performed.
    Type: Grant
    Filed: March 2, 2021
    Date of Patent: March 5, 2024
    Assignees: Preferred Networks, Inc., Tokyo Electron Limited
    Inventors: Kosuke Nakago, Daisuke Motoki, Masaki Watanabe, Tomoki Komatsu, Hironori Moki, Masanobu Honda, Takahiko Kato, Tomohiko Niizeki
  • Publication number: 20230414704
    Abstract: Compositions and methods useful for delivery of targeted therapies for pulmonary arterial hypertension, sepsis, cancer and cachexia. The compositions and methods are based on peptide pharmacophores that selectively bind to and home to diseased tissue and enable targeted therapies to affect a beneficial therapeutic result. Peptide pharmacophores may selectively target tumor vasculature, regenerating tissue, wounded tissue, inflamed tissue, fibrotic tissue, remodeled tissue, tissue characterized by elevated heparanase levels, and have the ability to internalize into such diseased cells.
    Type: Application
    Filed: May 8, 2023
    Publication date: December 28, 2023
    Inventors: David Mann, Erkki Ruoslahti, Masanobu Komatsu
  • Patent number: 11642391
    Abstract: Compositions and methods useful for delivery of targeted therapies for pulmonary arterial hypertension, sepsis, cancer and cachexia. The compositions and methods are based on peptide pharmacophores that selectively bind to and home to diseased tissue and enable targeted therapies to affect a beneficial therapeutic result. Peptide pharmacophores may selectively target tumor vasculature, regenerating tissue, wounded tissue, inflamed tissue, fibrotic tissue, remodeled tissue, tissue characterized by elevated heparanase levels, and have the ability to internalize into such diseased cells.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: May 9, 2023
    Assignee: Vascular Biosciences
    Inventors: David Mann, Erkki Ruoslahti, Masanobu Komatsu
  • Publication number: 20190134211
    Abstract: Disclosed are compositions and methods useful for delivering targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to effect a beneficial therapeutic result. The disclosed targeting is useful for delivering therapeutic and detectable agents to diseased tissue in an animal.
    Type: Application
    Filed: August 7, 2018
    Publication date: May 9, 2019
    Inventors: Masanobu Komatsu, David Mann, Erkki Ruoslahti
  • Publication number: 20190022170
    Abstract: Compositions and methods useful for delivery of targeted therapies for pulmonary arterial hypertension, sepsis, cancer and cachexia. The compositions and methods are based on peptide pharmacophores that selectively bind to and home to diseased tissue and enable targeted therapies to affect a beneficial therapeutic result. Peptide pharmacophores may selectively target tumor vasculature, regenerating tissue, wounded tissue, inflamed tissue, fibrotic tissue, remodeled tissue, tissue characterized by elevated heparanase levels, and have the ability to internalize into such diseased cells.
    Type: Application
    Filed: August 4, 2015
    Publication date: January 24, 2019
    Inventors: David Mann, Erkki Ruoslahti, Masanobu Komatsu
  • Patent number: 10039838
    Abstract: Disclosed are compositions and methods useful for delivering targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to effect a beneficial therapeutic result. The disclosed targeting is useful for delivering therapeutic and detectable agents to diseased tissue in an animal.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: August 7, 2018
    Assignees: Vascular Biosciences, Sanford-Burnham Medical Research Institute
    Inventors: Masanobu Komatsu, David Mann, Erkki Ruoslahti
  • Publication number: 20160184447
    Abstract: Disclosed are compositions and methods useful for delivering targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to effect a beneficial therapeutic result. The disclosed targeting is useful for delivering therapeutic and detectable agents to diseased tissue in an animal.
    Type: Application
    Filed: November 10, 2015
    Publication date: June 30, 2016
    Inventors: Masanobu Komatsu, David Mann, Erkki Ruoslahti
  • Patent number: 9180161
    Abstract: Disclosed are compositions and methods useful for delivering targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to effect a beneficial therapeutic result. The disclosed targeting is useful for delivering therapeutic and detectable agents to diseased tissue in an animal.
    Type: Grant
    Filed: February 28, 2011
    Date of Patent: November 10, 2015
    Assignees: Sanford Burnham Prebys Medical Discovery Institute, Vascular BioSciences
    Inventors: Masanobu Komatsu, David Marshall Mann, Erkki Ruoslahti
  • Patent number: 8506965
    Abstract: The invention provides means and methods for vascular regulation through enhancement or inhibition of R-Ras activity. The invention specifically provides means and methods for promoting a quiescent state of a vascular cell by providing additional R-Ras activity to the cell. The invention further provides means and methods for diagnosing a condition of vasculature of an individual.
    Type: Grant
    Filed: November 11, 2005
    Date of Patent: August 13, 2013
    Assignees: Vascular BioSciences, Sanford Burnham Medical Research Institute
    Inventors: Masanobu Komatsu, David Marshall Mann, Erkki Ruoslahti
  • Publication number: 20130196896
    Abstract: Disclosed are compositions and methods useful for delivering targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to effect a beneficial therapeutic result. The disclosed targeting is useful for delivering therapeutic and detectable agents to diseased tissue in an animal.
    Type: Application
    Filed: February 28, 2011
    Publication date: August 1, 2013
    Applicants: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE, VASCULAR BIOSCIENCES, INC.
    Inventors: Masanobu Komatsu, David Marshall Mann, Erkki Ruoslahti
  • Publication number: 20120034164
    Abstract: Disclosed are compositions and methods useful for targeting and internalizing molecules into cells of interest and for penetration by molecules of tissues of interest. The compositions and methods are based on peptide sequences, such as truncated CAR peptides, that are selectively internalized by a cell, penetrate tissue, or both. The disclosed internalization and tissue penetration is useful for delivering therapeutic and detectable agents to cells and tissues of interest.
    Type: Application
    Filed: September 1, 2011
    Publication date: February 9, 2012
    Inventors: Erkki Ruoslahti, Tero Järvinen, Masanobu Komatsu
  • Publication number: 20090304765
    Abstract: The invention provides means and methods for vascular regulation through enhancement or inhibition of R-Ras activity. The invention specifically provides means and methods for promoting a quiescent state of a vascular cell by providing additional R-Ras activity to the cell. The invention further provides means and methods for diagnosing a condition of vasculature of an individual.
    Type: Application
    Filed: November 11, 2005
    Publication date: December 10, 2009
    Inventors: Masanobu Komatsu, David Marshall Mann, Erkki Ruoslahti
  • Patent number: 4789417
    Abstract: A windowpane mounting system for mounting a windowpane on a vehicle body comprises a vehicle body conveyor for intermittently feeding the vehicle body, and a windowpane mounting robot for mounting a windowpane on the vehicle body at a windowpane mounting station. The windowpane mounting robot is arranged to be movable between a first mounting position for mounting one of the windowpanes for the windshield and the rear window and a second mounting position for mounting the other windowpane, the first mounting position being further than the second mounting position from a windowpane supply station at which the windowpane mounting robot receives the windowpanes, and is arranged to perform a mounting operation at the first mounting position in response to the feeding of the vehicle body to said windowpane mounting station by the vehicle body conveyor.
    Type: Grant
    Filed: October 27, 1986
    Date of Patent: December 6, 1988
    Assignee: Mazda Motor Corporation
    Inventors: Masanobu Komatsu, Takashi Senba, Hisao Miyahara, Kunzi Kimura, Shunji Sakamoto
  • Patent number: 4770120
    Abstract: A plate member locating-and-feeding system comprises a locating system for locating a plate member fed to a locating station, a position sensor for detecting the position of the plate member located by the locating system, a suction feeding system for holding the locating plate member under a suction force and feeding it to a working station, a working robot provided at the working station for performing a predetermined process and a controller which stores regular working position data, and corrects the regular working position data on the basis of difference between the position data represented by the output signal of the position sensor and the regular working position data, and controls the working robot to perform the predetermined process according to the corrected working position data.
    Type: Grant
    Filed: October 30, 1986
    Date of Patent: September 13, 1988
    Assignee: Mazda Motor Corporation
    Inventors: Masanobu Komatsu, Shigeo Okamizu