Patents by Inventor Masanobu Kusunoki
Masanobu Kusunoki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20220251489Abstract: An object is to provide a cell culture scaffold which makes it possible to recover a cell culture product without being destroyed after cell culturing and a method for producing a cell culture product. The cell culture scaffold according to the present invention includes a substrate having a water-repellent surface and a cell adhesion molecule formed on the water-repellent surface of the substrate. Further, the method for producing a cell culture product according to the present invention includes a step of culturing, using the cell culture scaffold, cells on the surface of the cell adhesion molecule. The cell culture scaffold according to the present invention makes it possible to recover the cells in a spheroid state without causing a damage.Type: ApplicationFiled: July 6, 2020Publication date: August 11, 2022Applicant: KINKI UNIVERSITYInventors: Masanobu KUSUNOKI, Hiroki TAKEUCHI, Hidetaka TOGO
-
Patent number: 9260780Abstract: This is a thin film forming apparatus which is equipped with a target constructed of a thin film material, a cathode for generating a particulate thin film material from the target, a supporting member for supporting the substrate on which the particulate thin film material is to be deposited, a heater for heating the substrate, and a guide for introducing the particulate thin film material onto a surface of the substrate where the thin film material is deposited, wherein the supporting member supports the substrate so as to expose the first principal surface and its backside (second principal surface) of the substrate, the target is disposed in a position for producing the particulate thin film material in an extension of the first principal surface of the substrate, and the guide is disposed on the first principal surface and the second principal surface of the substrate.Type: GrantFiled: March 26, 2004Date of Patent: February 16, 2016Assignee: TOHOKU SEIKI INDUSTRIES, LTD.Inventors: Masanobu Kusunoki, Keitaro Harada, Masayoshi Yokoo, Yoshinobu Takano
-
Patent number: 9205030Abstract: Provided are a hard tissue restoration material, which is excellent in hard tissue restoration ability, extremely effective in promoting recalcification of dental enamel, and excellent in protection properties and aesthetic properties, and a hard tissue restoration method. The hard tissue restoration material according to the present invention is a biocompatible ceramic film with flexibility and pliability that is obtained, for example, by immersing a substrate, having the biocompatible ceramic film formed thereon, in a solvent, which does not dissolve the biocompatible ceramic but dissolves at least a portion of the substrate, to dissolve or separate the substrate. Also, with the hard tissue restoration method according to the present invention, the hard tissue restoration material according to the present invention is bonded to or wound around a hard tissue defect site.Type: GrantFiled: January 29, 2013Date of Patent: December 8, 2015Assignee: KINKI UNIVERSITYInventors: Shigeki Hontsu, Hiroaki Nishikawa, Masanobu Kusunoki, Kazushi Yoshikawa, Kazuyo Yamamoto
-
Publication number: 20130236856Abstract: Provided are a hard tissue restoration material, which is excellent in hard tissue restoration ability, extremely effective in promoting recalcification of dental enamel, and excellent in protection properties and aesthetic properties, and a hard tissue restoration method. The hard tissue restoration material according to the present invention is a biocompatible ceramic film with flexibility and pliability that is obtained, for example, by immersing a substrate, having the biocompatible ceramic film formed thereon, in a solvent, which does not dissolve the biocompatible ceramic but dissolves at least a portion of the substrate, to dissolve or separate the substrate. Also, with the hard tissue restoration method according to the present invention, the hard tissue restoration material according to the present invention is bonded to or wound around a hard tissue defect site.Type: ApplicationFiled: January 29, 2013Publication date: September 12, 2013Applicant: KINKI UNIVERSITYInventors: Shigeki HONTSU, Hiroaki NISHIKAWA, Masanobu KUSUNOKI, Kazushi YOSHIKAWA, Kazuyo YAMAMOTO
-
Patent number: 8454987Abstract: The present invention provides a flexible, biocompatible transparent sheet (8) which has high biocompatibility and a high ability to adsorb a biologically relevant substance, which can be used as a novel biomaterial, and which can be used to observe the propagation, differentiation, and/or the like of living cells in real time. The biocompatible transparent sheet (8) is produced in such a manner that a biocompatible ceramic film (2) is formed on a substrate (1) soluble in a solvent (11) incapable of dissolving biocompatible ceramics by using exemplary a laser ablation process, the substrate (1) depositing the film (2) is dipped in the solvent (11) and dissolved off, and the isolated film (2) is then dried. The biocompatible transparent sheet (8) is utilizable of producing a flexible cultured cell sheet which can be directly transplanted to an affected area. The cell sheet can be prepared in such a manner that cells are seeded on the biocompatible transparent sheet (8) and then propagated.Type: GrantFiled: March 14, 2007Date of Patent: June 4, 2013Assignees: Kinki University, Japan Science and TechnologyInventors: Shigeki Hontsu, Hiroaki Nishikawa, Masanobu Kusunoki, Ryouta Hatanaka
-
Patent number: 8277750Abstract: Disclosed is a detector for chemical sensor devices, the detector being improved in detection sensitivity. Also disclosed is use of such a detector for chemical sensor devices. Specifically, disclosed is a detector for chemical sensor devices by which a substance to be measured is detected by adsorbing the substance contained in a medium on the surface thereof. The detector includes an adsorption layer containing hydroxyapatite or a substituted apatite obtained by substituting a part of elements in hydroxyapatite on a surface which is used for detecting the substance to be measured. Such a detector is greatly improved in detection sensitivity, and thus able to detect a very small amount of a chemical substance.Type: GrantFiled: August 30, 2005Date of Patent: October 2, 2012Assignee: Kinki UniversityInventors: Shigeki Hontsu, Masanobu Kusunoki, Hiroaki Nishikawa, Yoshiya Hashimoto, Izumi Yamada
-
Publication number: 20090311297Abstract: The present invention provides a flexible, biocompatible transparent sheet (8) which has high biocompatibility and a high ability to adsorb a biologically relevant substance, which can be used as a novel biomaterial, and which can be used to observe the propagation, differentiation, and/or the like of living cells in real time. The biocompatible transparent sheet (8) is produced in such a manner that a biocompatible ceramic film (2) is formed on a substrate (1) soluble in a solvent (11) incapable of dissolving biocompatible ceramics by using exemplary a laser ablation process, the substrate (1) depositing the film (2) is dipped in the solvent (11) and dissolved off, and the isolated film (2) is then dried. The biocompatible transparent sheet (8) is utilizable of producing a flexible cultured cell sheet which can be directly transplanted to an affected area. The cell sheet can be prepared in such a manner that cells are seeded on the biocompatible transparent sheet (8) and then propagated.Type: ApplicationFiled: March 14, 2007Publication date: December 17, 2009Inventors: Shigeki Hontsu, Hiroaki Nishikawa, Masanobu Kusunoki, Ryouta Hatanaka
-
Publication number: 20080202926Abstract: Disclosed is a detector for chemical sensor devices, the detector being improved in detection sensitivity. Also disclosed is use of such a detector for chemical sensor devices. Specifically, disclosed is a detector for chemical sensor devices by which a substance to be measured is detected by adsorbing the substance contained in a medium on the surface thereof. The detector includes an adsorption layer containing hydroxyapatite or a substituted apatite obtained by substituting a part of elements in hydroxyapatite on a surface which is used for detecting the substance to be measured. Such a detector is greatly improved in detection sensitivity, and thus able to detect a very small amount of a chemical substance.Type: ApplicationFiled: August 30, 2005Publication date: August 28, 2008Inventors: Shigeki Hontsu, Masanobu Kusunoki, Hiroaki Nishikawa, Yoshiya Hashimoto, Izumi Yamada
-
Publication number: 20080076269Abstract: This is a thin film forming apparatus which is equipped with a target constructed of a thin film material, a cathode for generating a particulate thin film material from the target, a supporting member for supporting the substrate on which the particulate thin film material is to be deposited, a heater for heating the substrate, and a guide for introducing the particulate thin film material onto a surface of the substrate where the thin film material is deposited, wherein the supporting member supports the substrate so as to expose the first principal surface and its backside (second principal surface) of the substrate, the target is disposed in a position for producing the particulate thin film material in an extension of the first principal surface of the substrate, and the guide is disposed on the first principal surface and the second principal surface of the substrate.Type: ApplicationFiled: March 26, 2004Publication date: March 27, 2008Inventors: Masanobu Kusunoki, Keitaro Harada, Masayoshi Yokoo, Yoshinobu Takano