Abstract: Provided is a drug superior for preventing and/or treating dementia. It contains a carbostyril derivative of the following formula (1) (wherein R is a cycloalkyl group, A is a lower alkyl group, and a single bond or a double bond is present between the 3-position and the 4-position of the carbostyril nucleus) and dihydroquercetin.

Abstract: This invention relates to a tissue construct comprising a core portion having a recess and composed of fibrous connective tissue, and loose fibrous somatic stem cell-accumulated tissue comprising type III collagen and somatic stem cells which is formed in the recess; a device for producing the same; and a method for collecting somatic stem cells from the tissue construct.

Abstract: The effect of physical exercise performed on a physical function of a subject with an irreversibly reduced physical function is promoted. Bone marrow mononuclear cells, CD34-positive cells, CD133-positive cells, or stem cells are contained. The central and peripheral nerves communicate intimately with each other. When these cells are administered to a subject, and the subject performs an appropriate physical exercise, the reduced physical function can be dramatically improved. The physical exercise .is, for example, physical exercise that stimulates both of brain and peripheral nerves based on the interactive biofeedback theory. Thus, for example, when bone marrow mononuclear cells are administered to a patient with a sequela of cerebral infarction, and the patient performs an appropriate physical exercise, the effect of functional recovery from the sequela of the cerebral infarction is promoted.

Abstract: The present invention reduces electric power consumption of a network inverter. The inverter (1a, 1b, 1c) includes: an MPU (20a, 20b, 20c); and a power supply (10) configured to carry out electric power delivery to the MPU (20a, 20b, 20c) and to a power source circuit (40). In a case where the inverter (1a, 1b, 1c) is to enter a standby state, an electric power delivery control circuit (22) of the MPU (20a, 20b, 20c) blocks electric power delivery to the power source circuit (40).

Abstract: A method may predict risk of onset of severe interstitial pneumonia caused by an immune checkpoint inhibitor to achieve a safe and highly effective cancer immunotherapy. Any one or more selected from: (a) cell count or proportion of V?2+?? T cells in peripheral blood mononuclear cells isolated from a subject; (b) cell count or proportion of V?2+?? T cells after antigenic stimulation in peripheral blood mononuclear cells isolated from a subject; (c) cell count or proportion of V?2+?? T cells in peripheral blood T cells isolated from a subject; and (d) cell count or proportion of V?2+?? T cells after antigenic stimulation in peripheral blood T cells isolated from a subject are measured, and the risk of onset of severe interstitial pneumonia is predicted by using the cell count or proportion as an index.

Abstract: The present invention provides an anticancer agent containing the following (1) and (2): (1) HVJ-E (hemagglutinating virus of Japan envelope), (2) an inhibitor of an immune checkpoint protein.

Abstract: In a technique for reducing the number of input terminals of a motor control device, flexibility of designing is improved. A terminal allocating section (23) is provided for setting, in accordance with selection by a user, which of a plurality of input terminals (11) is to be allocated to each of a plurality of function input terminals (21).

Abstract: Provided is a drug superior for preventing and/or treating dementia. It contains a carbostyril derivative of the following formula (1) (wherein R is a cycloalkyl group, A is a lower alkyl group, and a single bond or a double bond is present between the 3-position and the 4-position of the carbostyril nucleus) and dihydroquercetin.

Abstract: In a technique for reducing the number of input terminals of a motor control device, flexibility of designing is improved. A terminal allocating section (23) is provided for setting, in accordance with selection by a user, which of a plurality of input terminals (11) is to be allocated to each of a plurality of function input terminals (21).

Abstract: The present invention reduces electric power consumption of a network inverter. The inverter (1a, 1b, 1c) includes: an MPU (20a, 20b, 20c); and a power supply (10) configured to carry out electric power delivery to the MPU (20a, 20b, 20c) and to a power source circuit (40). In a case where the inverter (1a, 1b, 1c) is to enter a standby state, an electric power delivery control circuit (22) of the MPU (20a, 20b, 20c) blocks electric power delivery to the power source circuit (40).

Abstract: The present invention relates to a medicament for preventing and/or treating cognitive impairment and/or a neurodegenerative disease with accumulation of a prionoid, comprising a Sendai virus envelope as an active ingredient and combined application of the medicament and an immune checkpoint inhibitor.

Abstract: The present invention provides an anticancer agent containing the following (1) and (2): (1) HVJ-E (hemagglutinating virus of Japan envelope), (2) an inhibitor of an immune checkpoint protein.

Abstract: Provided is a drug superior for preventing and/or treating dementia. It contains a carbostyril derivative of the following formula (1) (wherein R is a cycloalkyl group, A is a lower alkyl group, and a single bond or a double bond is present between the 3-position and the 4-position of the carbostyril nucleus) and dihydroquercetin.

Abstract: Provided is a pharmaceutical composition, including a drug and a collagen, in which the composition is satisfactory in handleability and has sustained-release property. The sustained-release pharmaceutical composition includes: a drug; a collagen; and at least one kind of sugar selected from monosaccharides, disaccharides, trisaccharides, and tetrasaccharides. The inventors of the present invention have found that the in vivo administration of a collagen solution containing a sugar results in the gelation of a collagen. Based on this finding, the inventors have found that a composition containing a drug, a collagen, and a sugar can control the release rate of the drug, and such composition can be used as a sustained-release pharmaceutical composition.

Abstract: Provided is a pharmaceutical composition, including a drug and a collagen, in which the composition is satisfactory in handleability and has sustained-release property. The sustained-release pharmaceutical composition includes: a drug; a collagen; and at least one kind of sugar selected from monosaccharides, disaccharides, trisaccharides, and tetrasaccharides. The inventors of the present invention have found that the in vivo administration of a collagen solution containing a sugar results in the gelation of a collagen. Based on this finding, the inventors have found that a composition containing a drug, a collagen, and a sugar can control the release rate of the drug, and such composition can be used as a sustained-release pharmaceutical composition.

Abstract: A programmable controller includes two CPU units each having a detachably attached special-function module for carrying out a calculation process, each of the two CPU units recognizing conditions of the other CPU unit, one of them becoming an active unit and the other becoming a standby unit such that when the active unit fails and goes down the standby unit is switched to become active and resumes operations. The special-function module attached to the active CPU unit becomes an active module and carries out control processes with the active CPU unit and the other special-function module attached to the standby CPU unit becomes a standby module.

Abstract: A programmable controller includes two CPU units each having a detachably attached special-function module for carrying out a calculation process, each of the two CPU units recognizing conditions of the other CPU unit, one of them becoming an active unit and the other becoming a standby unit such that when the active unit fails and goes down the standby unit is switched to become active and resumes operations. The special-function module attached to the active CPU unit becomes an active module and carries out control processes with the active CPU unit and the other special-function module attached to the standby CPU unit becomes a standby module.

Abstract: The rotating pile for undergrounding contains a pile-head pipe having a longitudinal center line, a pipe wall, one end portion, and the other end portion opposite to the one end portion. Three or four recessed portions in which the pipe wall is recessed toward the center line are formed in the one end portion. Blades defined by the pipe wall are formed between the adjacent recessed portions. Each of the recessed portions is inclined from the circumferential surface of the pile-head pipe toward the center line. The pipe wall defining one of the adjacent recessed portions contact with the pipe wall defining the other recessed portion so as to cause the one end to be substantially closed. The blades extend radially outward from the center line. The blades gradually expand in the circumferential direction of the pile-head pipe from its top end toward its base end portion.

Abstract: The rotating pile for undergrounding contains a pile-head pipe having a longitudinal center line, a pipe wall, one end portion, and the other end portion opposite to the one end portion. Three or four recessed portions in which the pipe wall is recessed toward the center line are formed in the one end portion. Blades defined by the pipe wall are formed between the adjacent recessed portions. Each of the recessed portions is inclined from the circumferential surface of the pile-head pipe toward the center line. The pipe wall defining one of the adjacent recessed portions contact with the pipe wall defining the other recessed portion so as to cause the one end to be substantially closed. The blades extend radially outward from the center line. The blades gradually expand in the circumferential direction of the pile-head pipe from its top end toward its base end portion.

Abstract: In the polishing system of the present invention, a adhering unit adheres a wafer on a carrying plate using liquid. A polishing unit polishes the wafer using a polishing plate. A feeding unit conveys the carrying plate from the adhering unit to the polishing unit. A dismounting unit removes the wafer from the carrying plate. A first discharging unit conveys the carrying plate from the polishing unit to the dismounting unit. A cleaning unit cleans the vacant carrying plate. A second discharging unit conveys the carrying plate from the dismounting unit to the cleaning unit. A third discharging unit conveys the carrying plate from the cleaning unit to the adhering unit. The units are formed into a loop lines so that the carrying plate is circulated in the loop line and the wafers are polished therein.